PDB: 101 resultsInfo pagesStatus searchChemie searchBIRD

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4KK9	Structure of the E148A mutant of CLC-ec1 deltaNC construct in 100mM fluoride and 2mM Bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2013-11-13 Method: X-RAY DIFFRACTION (2.997 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
7CQ6	Structure of the human CLCN7-OSTM1 complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, H(+)/Cl(-) exchange transporter 7, ... Authors: Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L. Deposit date: 2020-08-08 Release date: 2020-11-11 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structure of the human CLCN7-OSTM1 complex To Be Published
1KPL	Crystal Structure of the ClC Chloride Channel from S. typhimurium Descriptor: CHLORIDE ION, N-OCTANE, PENTADECANE, ... Authors: Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R. Deposit date: 2001-12-31 Release date: 2002-01-23 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3 Å) Cite: X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity. Nature, 415, 2002
4KKA	Structure of the E148A mutant of CLC-ec1 deltaNC construct in 100mM fluoride and 20mM Bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2013-11-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
1OTT	Structure of the Escherichia coli ClC Chloride channel E148A mutant and Fab Complex Descriptor: CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... Authors: Dutzler, R, Campbell, E.B, MacKinnon, R. Deposit date: 2003-03-23 Release date: 2003-04-15 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (3 Å) Cite: Gating the Selectivity Filter in ClC Chloride Channels Science, 300, 2003
7CVS	Crystal structure of the C85A/L194A mutant CLC-ec1 with Fab fragment Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment heavy chain, ... Authors: Park, K, Mersch, K, Robertson, J, Lim, H.-H. Deposit date: 2020-08-27 Release date: 2021-09-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.01 Å) Cite: Altering CLC stoichiometry by reducing non-polar side-chains at the dimerization interface. J.Mol.Biol., 433, 2021
4FG6	Structure of EcCLC E148A mutant in Glutamate Descriptor: Fab fragment (Heavy chain), Fab fragment (Light chain), H(+)/Cl(-) exchange transporter ClcA Authors: Feng, L, MacKinnon, R. Deposit date: 2012-06-04 Release date: 2012-07-04 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.019 Å) Cite: Molecular mechanism of proton transport in CLC Cl-/H+ exchange transporters. Proc.Natl.Acad.Sci.USA, 109, 2012
4KKB	Structure of the E148A mutant of CLC-ec1 deltaNC construct in 20mM fluoride and 20mM Bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2013-11-13 Method: X-RAY DIFFRACTION (3.021 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KJW	Structure of the CLC-ec1 deltaNC construct in 100mM fluoride and 20mM bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-03 Release date: 2013-08-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.03 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
6ADC	Crystal structure of the E148A mutant CLC-ec1 in the presence of 50mM bromoacetate Descriptor: H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment, heavy chain, ... Authors: Lim, H.-H, Park, K. Deposit date: 2018-07-31 Release date: 2019-08-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.055 Å) Cite: Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter. Proc.Natl.Acad.Sci.USA, 116, 2019
8JEV	Cryo-EM structure of apo state mClC-3 Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter 3 Authors: Wan, Y.Z.Q, Yang, F. Deposit date: 2023-05-16 Release date: 2024-09-04 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Structural basis of adenine nucleotides regulation and neurodegenerative pathology in ClC-3 exchanger. Nat Commun, 15, 2024
8GA3	CLC-ec1 R230C/L249C/C85A at pH 4.5 100mM Cl Turn Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA Authors: Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A. Deposit date: 2023-02-22 Release date: 2024-02-07 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of pH-dependent activation in a CLC transporter. Nat.Struct.Mol.Biol., 31, 2024
2R9H	Crystal Structure of Q207C Mutant of CLC-ec1 in complex with Fab Descriptor: CHLORIDE ION, Fab fragment, H(+)/Cl(-) exchange transporter clcA Authors: Nguitragool, W, Miller, C. Deposit date: 2007-09-12 Release date: 2007-11-20 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Crystal Structure of Q207C Mutant of CLC-ec1 in complex with Fab To be Published
3NMO	Crystal structure of an engineered monomeric CLC-ec1 Cl-/H+ transporter Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter clcA Authors: Robertson, J.L, Kolmakova-Partensky, L, Miller, C. Deposit date: 2010-06-22 Release date: 2010-07-21 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Design, function and structure of a monomeric ClC transporter. Nature, 468, 2010
2H2S	Crystal Structure of E148A mutant of CLC-ec1 in SeCN- Descriptor: CLC Cl transporter, FAB fragment, heavy chain, ... Authors: Nguitragool, W, Miller, C. Deposit date: 2006-05-19 Release date: 2006-05-30 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Uncoupling of a CLC Cl(-)/H(+) Exchange Transporter by Polyatomic Anions J.Mol.Biol., 362, 2006
2H2P	Crystal structure of CLC-ec1 in complex with Fab fragment in SeCN- Descriptor: CLC Cl transporter, FAB fragment, heavy chain, ... Authors: Nguitragool, W, Miller, C. Deposit date: 2006-05-19 Release date: 2006-05-30 Last modified: 2017-10-18 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Uncoupling of a CLC Cl(-)/H(+) Exchange Transporter by Polyatomic Anions J.Mol.Biol., 362, 2006
2EXY	Crystal structure of the E148Q Mutant of EcClC, Fab complexed in absence of bound ions Descriptor: Fab Fragment (Heavy Chain), Fab Fragment (Light Chain), H(+)/Cl(-) exchange transporter clcA Authors: Lobet, S, Dutzler, R. Deposit date: 2005-11-09 Release date: 2006-01-24 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Ion-binding properties of the ClC chloride selectivity filter. Embo J., 25, 2006
5HD8	Crystal structure of disulfide cross-linked D417C ClC-ec1 Descriptor: CHLORIDE ION, FAB FRAGMENT (HEAVY CHAIN), FAB FRAGMENT (LIGHT CHAIN), ... Authors: Mathews, I.I, Khantwal, C.M, Maduke, M. Deposit date: 2016-01-05 Release date: 2017-01-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Conformational change in CLC transporters: beyond the rotation of Gluex To be published
6ADA	Crystal structure of the E148D mutant CLC-ec1 in 200mM bromide Descriptor: BROMIDE ION, H(+)/Cl(-) exchange transporter ClcA, antibody Fab fragment, ... Authors: Lim, H.-H, Park, K. Deposit date: 2018-07-31 Release date: 2019-08-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.153 Å) Cite: Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter. Proc.Natl.Acad.Sci.USA, 116, 2019
8IAD	The Arabidopsis CLCa transporter bound with nitrate, ATP and PIP2 Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Chloride channel protein CLC-a, MAGNESIUM ION, ... Authors: Yang, Z, Zhang, X, Zhang, P. Deposit date: 2023-02-08 Release date: 2023-08-02 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Molecular mechanism underlying regulation of Arabidopsis CLCa transporter by nucleotides and phospholipids. Nat Commun, 14, 2023
4KK5	Structure of the CLC-ec1 deltaNC construct in 20mM fluoride and 20mM bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2013-11-13 Method: X-RAY DIFFRACTION (3.171 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KKC	Structure of the E148A mutant of CLC-ec1 deltaNC construct in 20mM Bromide Descriptor: Fab, heavy chain, light chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2013-12-04 Method: X-RAY DIFFRACTION (3.18 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KK6	Structure of CLC-ec1 deltaNC construct in 20mM Bromide Descriptor: BROMIDE ION, Fab, heavy chain, ... Authors: Lim, H.-H, Miller, C. Deposit date: 2013-05-05 Release date: 2013-08-21 Last modified: 2013-11-13 Method: X-RAY DIFFRACTION (3.183 Å) Cite: Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
2FEE	Structure of the Cl-/H+ exchanger CLC-ec1 from E.Coli in NaBr Descriptor: Fab fragment, heavy chain, light chain, ... Authors: Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C. Deposit date: 2005-12-15 Release date: 2006-01-03 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Separate ion pathways in a Cl-/H+ exchanger J.Gen.Physiol., 126, 2005
2HT4	Structure of the Escherichia coli ClC chloride channel Y445W mutant and Fab complex Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ... Authors: Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. Deposit date: 2006-07-25 Release date: 2006-09-19 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger. J.Mol.Biol., 362, 2006

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