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4IX8
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Crystal structure of Tyrosine aminotransferase from Leishmania infantum
Descriptor: CHLORIDE ION, Tyrosine aminotransferase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-01-24
Release date:2014-03-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of tyrosine aminotransferase from Leishmania infantum.
Acta Crystallogr F Struct Biol Commun, 70, 2014
4J8L
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CRYSTAL STRUCTURE OF THE PYRIDOXAL-5'-PHOSPHATE DEPENDENT protein YhfS from Escherichia coli
Descriptor: ACETIC ACID, DI(HYDROXYETHYL)ETHER, NICKEL (II) ION, ...
Authors:Fedorov, A.A, Fedorov, E.V, Xiang, D.F, Raushel, F.M, Almo, S.C.
Deposit date:2013-02-14
Release date:2014-03-05
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:Crystal structure of the pyridoxal-5'-phosphate dependent protein yhfs from escherichia coli
To be Published
4JE5
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Crystal structure of the aromatic aminotransferase Aro8, a putative alpha-aminoadipate aminotransferase in Saccharomyces cerevisiae
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Aromatic/aminoadipate aminotransferase 1, ...
Authors:Bulfer, S.L, Brunzelle, J.S, Trievel, R.C.
Deposit date:2013-02-26
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.909 Å)
Cite:Crystal structure of Saccharomyces cerevisiae Aro8, a putative alpha-aminoadipate aminotransferase.
Protein Sci., 22, 2013
2W8V
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SPT with PLP, N100W
Descriptor: PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE
Authors:Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
Deposit date:2009-01-19
Release date:2009-01-27
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2W8J
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SPT with PLP-ser
Descriptor: SERINE PALMITOYLTRANSFERASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE
Authors:Carter, L.G, Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
Deposit date:2009-01-16
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2W8T
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SPT with PLP, N100C
Descriptor: PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE
Authors:Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
Deposit date:2009-01-19
Release date:2009-01-27
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2W8W
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N100Y SPT with PLP-ser
Descriptor: SERINE PALMITOYLTRANSFERASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE
Authors:Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
Deposit date:2009-01-19
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2W8U
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SPT with PLP, N100Y
Descriptor: PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE
Authors:Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
Deposit date:2009-01-19
Release date:2009-01-27
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2WKA
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Structure of Plp_Thr_decanoyl-CoA aldimine form of Vibrio cholerae CqsA
Descriptor: CAI-1 AUTOINDUCER SYNTHASE, CHLORIDE ION, SULFATE ION, ...
Authors:Jahan, N, Potter, J.A, Sheikh, M.A, Botting, C.H, Shirran, S.L, Westwood, N.J, Taylor, G.L.
Deposit date:2009-06-08
Release date:2009-07-21
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Insights Into the Biosynthesis of the Vibrio Cholerae Major Autoinducer Cai-1 from the Crystal Structure of the Plp-Dependent Enzyme Cqsa.
J.Mol.Biol., 392, 2009
2WK7
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Structure of apo form of Vibrio cholerae CqsA
Descriptor: CAI-1 AUTOINDUCER SYNTHASE, SULFATE ION
Authors:Jahan, N, Potter, J.A, Sheikh, M.A, Botting, C.H, Shirran, S.L, Westwood, N.J, Taylor, G.L.
Deposit date:2009-06-08
Release date:2009-07-21
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights Into the Biosynthesis of the Vibrio Cholerae Major Autoinducer Cai-1 from the Crystal Structure of the Plp-Dependent Enzyme Cqsa.
J.Mol.Biol., 392, 2009
2X5D
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Crystal Structure of a probable aminotransferase from Pseudomonas aeruginosa
Descriptor: PROBABLE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
Authors:Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H.
Deposit date:2010-02-08
Release date:2010-07-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genom., 11, 2010
2WK8
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Structure of holo form of Vibrio cholerae CqsA
Descriptor: CAI-1 AUTOINDUCER SYNTHASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
Authors:Jahan, N, Potter, J.A, Sheikh, M.A, Botting, C.H, Shirran, S.L, Westwood, N.J, Taylor, G.L.
Deposit date:2009-06-08
Release date:2009-07-21
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights Into the Biosynthesis of the Vibrio Cholerae Major Autoinducer Cai-1 from the Crystal Structure of the Plp-Dependent Enzyme Cqsa.
J.Mol.Biol., 392, 2009
2WK9
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Structure of Plp_Thr aldimine form of Vibrio cholerae CqsA
Descriptor: CAI-1 AUTOINDUCER SYNTHASE, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Jahan, N, Potter, J.A, Sheikh, M.A, Botting, C.H, Shirran, S.L, Westwood, N.J, Taylor, G.L.
Deposit date:2009-06-08
Release date:2009-07-21
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights Into the Biosynthesis of the Vibrio Cholerae Major Autoinducer Cai-1 from the Crystal Structure of the Plp-Dependent Enzyme Cqsa.
J.Mol.Biol., 392, 2009
2XBN
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Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, MAGNESIUM ION, SERINE PALMITOYLTRANSFERASE
Authors:Lowther, J, Yard, B.A, Johnson, K.A, Carter, L.G, Bhat, V.T, Raman, M.C.C, Clarke, D.J, Ramakers, B, McMahon, S.A, Naismith, J.H, Campopiano, D.J.
Deposit date:2010-04-13
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Inhibition of the Plp-Dependent Enzyme Serine Palmitoyltransferase by Cycloserine: Evidence for a Novel Decarboxylative Mechanism of Inactivation.
Mol.Biosystems, 6, 2010
2XH1
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Crystal structure of human KAT II-inhibitor complex
Descriptor: (3S)-10-(4-AMINOPIPERAZIN-1-YL)-9-FLUORO-7-HYDROXY-3-METHYL-2,3-DIHYDRO-8H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLATE, GLYCEROL, IODIDE ION, ...
Authors:Rossi, F, Casazza, V, Garavaglia, S, Sathyasaikumar, K.V, Schwarcz, R, Kojima, S.I, Okuwaki, K, Ono, S.I, Kajii, Y, Rizzi, M.
Deposit date:2010-06-08
Release date:2010-07-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure-Based Selective Targeting of the Pyridoxal 5'-Phsosphate Dependent Enzyme Kynurenine Aminotransferase II for Cognitive Enhancement
J.Med.Chem., 53, 2010
2Z1Y
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Crystal structure of LysN, alpha-aminoadipate aminotransferase (complexed with N-(5'-phosphopyridoxyl)-L-leucine), from Thermus thermophilus HB27
Descriptor: Alpha-aminodipate aminotransferase, LEUCINE, PYRIDOXAL-5'-PHOSPHATE
Authors:Tomita, T, Miyazaki, T, Miyagawa, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M.
Deposit date:2007-05-16
Release date:2008-06-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mechanism of broad substrate specificity of alpha-aminoadipate aminotransferase from Thermus thermophilus
To be Published
2Z20
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Crystal structure of LL-Diaminopimelate Aminotransferase from Arabidopsis thaliana
Descriptor: GLYCEROL, LL-diaminopimelate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Watanabe, N, Cherney, M.M, van Belkum, M.J, Marcus, S.L, Flegel, M.D, Clay, M.D, Deyholos, M.K, Vederas, J.C, James, M.N.G.
Deposit date:2007-05-17
Release date:2007-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana: a recently discovered enzyme in the biosynthesis of L-lysine by plants and Chlamydia
J.Mol.Biol., 371, 2007
2Z61
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Crystal structure of MJ0684 from Methanococcus jannaschii reveals its similarity in the active site to kynurenine aminotransferases
Descriptor: Probable aspartate aminotransferase 2
Authors:Yang, J.K.
Deposit date:2007-07-21
Release date:2008-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of MJ0684 from Methanococcus jannaschii, a Novel Archaeal Homolog of Kynurenine Aminotransferase
BULL.KOREAN CHEM.SOC., 29, 2008
2Z1Z
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Crystal structure of LL-Diaminopimelate Aminotransferase from Arabidopsis thaliana complexed with L-malate ion
Descriptor: D-MALATE, LL-diaminopimelate aminotransferase, PYRIDOXAL-5'-PHOSPHATE
Authors:Watanabe, N, Cherney, M.M, van Belkum, M.J, Marcus, S.L, Flegel, M.D, Clay, M.D, Deyholos, M.K, Vederas, J.C, James, M.N.G.
Deposit date:2007-05-16
Release date:2007-07-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana: a recently discovered enzyme in the biosynthesis of L-lysine by plants and Chlamydia
J.Mol.Biol., 371, 2007
2ZC0
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Crystal structure of an archaeal alanine:glyoxylate aminotransferase
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Alanine glyoxylate transaminase, IMIDAZOLE, ...
Authors:Sakuraba, H, Yoneda, K, Tsuge, H, Ohshima, T.
Deposit date:2007-10-31
Release date:2008-06-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of an archaeal alanine:glyoxylate aminotransferase
Acta Crystallogr.,Sect.D, 64, 2008
2ZJG
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Crystal structural of mouse kynurenine aminotransferase III
Descriptor: GLYCEROL, Kynurenine-oxoglutarate transaminase 3
Authors:Han, Q, Cai, T, Tagle, D.A, Robinson, H, Li, J.
Deposit date:2008-03-07
Release date:2009-01-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and functional characterization of mouse kynurenine aminotransferase III
To be Published
2ZP7
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Crystal structure of LysN, alpha-aminoadipate aminotransferase (Leucine complex), from Thermus thermophilus HB27
Descriptor: Alpha-aminodipate aminotransferase, LEUCINE, PYRIDOXAL-5'-PHOSPHATE
Authors:Tomita, T, Miyazaki, T, Miyagawa, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M.
Deposit date:2008-06-30
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Mechanism for multiple-substrates recognition of alpha-aminoadipate aminotransferase from Thermus thermophilus
Proteins, 2008
2ZYJ
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Crystal structure of LysN, alpha-aminoadipate aminotransferase (complexed with N-(5'-phosphopyridoxyl)-L-glutamate), from Thermus thermophilus HB27
Descriptor: Alpha-aminodipate aminotransferase, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-glutamic acid
Authors:Ouchi, T, Tomita, T, Kuzuyama, T, Nishiyama, M.
Deposit date:2009-01-26
Release date:2009-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Dual roles of a conserved pair, Arg23 and Ser20, in recognition of multiple substrates in alpha-aminoadipate aminotransferase from Thermus thermophilus.
Biochem.Biophys.Res.Commun., 388, 2009
2ZY5
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R487A mutant of L-aspartate beta-decarboxylase
Descriptor: L-aspartate beta-decarboxylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Chen, H.-J, Ko, T.-P, Lee, C.-Y, Wang, N.-C, Wang, A.H.-J.
Deposit date:2009-01-13
Release date:2009-01-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure, Assembly, and Mechanism of a PLP-Dependent Dodecameric l-Aspartate beta-Decarboxylase
Structure, 17, 2009
2ZY2
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dodecameric L-aspartate beta-decarboxylase
Descriptor: L-aspartate 4-carboxylyase, PYRIDOXAL-5'-PHOSPHATE
Authors:Chen, H.-J, Ko, T.-P, Lee, C.-Y, Wang, N.-C, Wang, A.H.-J.
Deposit date:2009-01-13
Release date:2009-01-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure, Assembly, and Mechanism of a PLP-Dependent Dodecameric l-Aspartate beta-Decarboxylase
Structure, 17, 2009

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