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4V2A
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BU of 4v2a by Molmil
human Unc5A ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NETRIN RECEPTOR UNC5A
Authors:Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
7AHS
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BU of 7ahs by Molmil
titin-N2A Ig81-Ig83
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Isoform 5 of Titin, ...
Authors:Fleming, J.R, Mayans, O.
Deposit date:2020-09-25
Release date:2021-03-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The N2A region of titin has a unique structural configuration.
J.Gen.Physiol., 153, 2021
5MO9
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BU of 5mo9 by Molmil
Structure of human TrkB receptor ligand binding domain in complex with the Fab frgment of antibody AB20
Descriptor: AB20 Fab heavy chain, AB20 Fab light chain, BDNF/NT-3 growth factors receptor
Authors:Hoerer, S.
Deposit date:2016-12-14
Release date:2017-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Pharmaceutical Characterization of Tropomyosin Receptor Kinase B-Agonistic Antibodies on Human Induced Pluripotent Stem (hiPS) Cell-Derived Neurons.
J. Pharmacol. Exp. Ther., 361, 2017
2A38
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BU of 2a38 by Molmil
Crystal structure of the N-Terminus of titin
Descriptor: CADMIUM ION, Titin
Authors:Marino, M, Muhle-Goll, C, Svergun, D, Demirel, M, Mayans, O.
Deposit date:2005-06-24
Release date:2006-06-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Ig doublet Z1Z2: a model system for the hybrid analysis of conformational dynamics in Ig tandems from titin
Structure, 14, 2006
1GXE
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BU of 1gxe by Molmil
Central domain of cardiac myosin binding protein C
Descriptor: MYOSIN BINDING PROTEIN C, CARDIAC-TYPE
Authors:Pfuhl, M.
Deposit date:2002-04-03
Release date:2003-06-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure, Stability and Dynamics of the Central Domain of Cardiac Myosin Binding Protein C (Mybp-C): Implications for Multidomain Assembly and Causes for Cardiomyopathy
J.Mol.Biol., 329, 2003
6J6Y
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BU of 6j6y by Molmil
FGFR4 D2 - Fab complex
Descriptor: Fab Heavy chain, Fab light chain, Fibroblast growth factor receptor 4
Authors:Takahashi, M, Hanzawa, H.
Deposit date:2019-01-16
Release date:2019-08-07
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Preclinical Development of U3-1784, a Novel FGFR4 Antibody Against Cancer, and Avoidance of Its On-target Toxicity.
Mol.Cancer Ther., 18, 2019
3KVQ
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BU of 3kvq by Molmil
Crystal structure of VEGFR2 extracellular domain D7
Descriptor: Vascular endothelial growth factor receptor 2
Authors:Yang, Y, Opatowsky, Y, Xie, P, Schlessinger, J.
Deposit date:2009-11-30
Release date:2010-02-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling
Proc.Natl.Acad.Sci.USA, 107, 2010
6I9S
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BU of 6i9s by Molmil
hRobo2 Extracellular Domains 2-3
Descriptor: Roundabout homolog 2, SODIUM ION
Authors:Barak, R, Isupov, N.M, Opatowsky, Y.
Deposit date:2018-11-25
Release date:2019-03-13
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural Principles in Robo Activation and Auto-inhibition.
Cell, 177, 2019
3GRW
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BU of 3grw by Molmil
FGFR3 in complex with a Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
Authors:Wiesmann, C.
Deposit date:2009-03-26
Release date:2009-05-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice.
J.Clin.Invest., 119, 2009
6MG9
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BU of 6mg9 by Molmil
Human Obscurin Ig57 Domain
Descriptor: Obscurin
Authors:Wright, N.T, Whitley, J.A.
Deposit date:2018-09-13
Release date:2019-02-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Obscurin is a semi-flexible molecule in solution.
Protein Sci., 28, 2019
6SDB
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BU of 6sdb by Molmil
Chimeric titin Z1Z2 functionalized with a KLER exogenous peptide from decorin
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, PHOSPHATE ION, ...
Authors:Fleming, J.R, Hill, C, Mayans, O.M.
Deposit date:2019-07-26
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The ZT Biopolymer: A Self-Assembling Protein Scaffold for Stem Cell Applications.
Int J Mol Sci, 20, 2019
5JDE
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BU of 5jde by Molmil
Crystal structure of I9-I11 tandem from titin (P1)
Descriptor: Titin
Authors:Williams, R, Bogomolovas, J, Labiet, S, Mayans, O.
Deposit date:2016-04-16
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I.
Open Biology, 6, 2016
3KNB
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BU of 3knb by Molmil
Crystal structure of the titin C-terminus in complex with obscurin-like 1
Descriptor: Obscurin-like protein 1, SULFATE ION, Titin
Authors:Sauer, F, Vahokoski, J, Wilmanns, M.
Deposit date:2009-11-12
Release date:2009-12-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin.
Embo Rep., 11, 2010
3LCY
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BU of 3lcy by Molmil
Titin Ig tandem domains A164-A165
Descriptor: Titin
Authors:Chen, Q, Groves, M.R, Wilmanns, M.
Deposit date:2010-01-12
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural investigation of the Titin A-band tandem Ig domains A164-A165
To be Published
6YJ0
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BU of 6yj0 by Molmil
Solution NMR structure of titin N2A region Ig domain I83
Descriptor: Titin
Authors:Pfuhl, M, Gage, M.
Deposit date:2020-04-02
Release date:2021-04-14
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Solution NMR Structure of Titin N2A Region Ig Domain I83 and Its Interaction with Metal Ions.
J.Mol.Biol., 433, 2021
7LU6
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BU of 7lu6 by Molmil
Crystal structure of the mouse Kirrel3 D1 homodimer
Descriptor: Kin of IRRE-like protein 3, SODIUM ION
Authors:Roman, C.A, Pak, J.S, Wang, J, Ozkan, E.
Deposit date:2021-02-21
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors.
Cell Rep, 37, 2021
7R67
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BU of 7r67 by Molmil
Human obscurin Ig13
Descriptor: Obscurin
Authors:Moncure, G.E, Wright, N.T.
Deposit date:2021-06-22
Release date:2022-11-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The N-terminus of obscurin is flexible in solution.
Proteins, 91, 2023
7R68
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BU of 7r68 by Molmil
Human obscurin Ig12
Descriptor: Obscurin
Authors:Mauriello, G.E, Wright, N.T.
Deposit date:2021-06-22
Release date:2022-11-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The N-terminus of obscurin is flexible in solution.
Proteins, 91, 2023
2WWM
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BU of 2wwm by Molmil
Crystal structure of the Titin M10-Obscurin like 1 Ig complex in space group P1
Descriptor: OBSCURIN-LIKE PROTEIN 1, TITIN
Authors:Pernigo, S, Fukuzawa, A, Gautel, M, Steiner, R.A.
Deposit date:2009-10-26
Release date:2010-02-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insight Into M-Band Assembly and Mechanics from the Titin-Obscurin-Like-1 Complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WP3
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BU of 2wp3 by Molmil
Crystal structure of the Titin M10-Obscurin like 1 Ig complex
Descriptor: GLYCEROL, OBSCURIN-LIKE PROTEIN 1, SULFATE ION, ...
Authors:Pernigo, S, Fuzukawa, A, Gautel, M, Steiner, R.A.
Deposit date:2009-08-02
Release date:2010-02-16
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural Insight Into M-Band Assembly and Mechanics from the Titin-Obscurin-Like-1 Complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
7SJL
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BU of 7sjl by Molmil
Solution NMR Structure of Immunoglobulin-like Domain of Human Neuregulin-1
Descriptor: Neuregulin-1
Authors:Eletsky, A, Kim, Y, Rogals, M.J, Prestegard, J.H.
Deposit date:2021-10-18
Release date:2022-05-18
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Validated determination of NRG1 Ig-like domain structure by mass spectrometry coupled with computational modeling
Commun Biol, 5, 2022
4QEG
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BU of 4qeg by Molmil
Crystal structure of domain I10 from titin (space group P41)
Descriptor: CALCIUM ION, Titin
Authors:Bogomolovas, J, Labeit, S, Mayans, O.
Deposit date:2014-05-16
Release date:2015-07-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Exploration of the pathological potential of isolated mSNPs in titin: the cardiomyopathy-linked mutation T2580I
Open Biology, 2016
1NCU
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BU of 1ncu by Molmil
Titin Module M5, N-terminally Extended, NMR
Descriptor: TITIN
Authors:Pfuhl, M, Pastore, A.
Deposit date:1996-08-13
Release date:1996-11-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:When a module is also a domain: the role of the N terminus in the stability and the dynamics of immunoglobulin domains from titin.
J.Mol.Biol., 265, 1997
1NCT
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BU of 1nct by Molmil
TITIN MODULE M5, N-TERMINALLY EXTENDED, NMR
Descriptor: TITIN
Authors:Pfuhl, M, Pastore, A.
Deposit date:1996-08-13
Release date:1996-11-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:When a module is also a domain: the role of the N terminus in the stability and the dynamics of immunoglobulin domains from titin.
J.Mol.Biol., 265, 1997
1PD6
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BU of 1pd6 by Molmil
The NMR structure of domain C2 of human cardiac Myosin Binding Protein C
Descriptor: Myosin-binding protein C, cardiac-type, Domain C2
Authors:Ababou, A, Gautel, M, Pfuhl, M.
Deposit date:2003-05-19
Release date:2004-08-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Dissecting the N-terminal myosin binding site of human cardiac myosin-binding protein C. Structure and myosin binding of domain C2
J.Biol.Chem., 282, 2007

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數據於2024-09-18公開中

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