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6IDO
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BU of 6ido by Molmil
Crystal structure of Klebsiella pneumoniae sigma4 of sigmaS fusing with the RNA polymerase beta-flap-tip-helix in complex with -35 element DNA
Descriptor: DNA (5'-D(P*CP*CP*AP*CP*TP*TP*GP*AP*CP*AP*AP*AP*TP*CP*G)-3'), DNA (5'-D(P*GP*AP*TP*TP*TP*GP*TP*CP*AP*AP*GP*TP*GP*GP*C)-3'), RNA polymerase sigma factor RpoS,RNA polymerase beta-flap-tip-helix
Authors:Lou, Y.C, Chien, C.Y, Chen, C, Hsu, C.H.
Deposit date:2018-09-10
Release date:2019-09-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.748 Å)
Cite:Structural basis for -35 element recognition by sigma4chimera proteins and their interactions with PmrA response regulator.
Proteins, 88, 2020
6FI7
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BU of 6fi7 by Molmil
E.coli Sigma factor S (RpoS) Region 4
Descriptor: RNA polymerase sigma factor RpoS
Authors:Liu, B, Matthews, S.J.
Deposit date:2018-01-17
Release date:2018-06-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:T7 phage factor required for managing RpoS inEscherichia coli.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1TTY
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BU of 1tty by Molmil
Solution structure of sigma A region 4 from Thermotoga maritima
Descriptor: RNA polymerase sigma factor rpoD
Authors:Lambert, L.J, Wei, Y, Schirf, V, Demeler, B, Werner, M.H.
Deposit date:2004-06-23
Release date:2004-11-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:T4 AsiA blocks DNA recognition by remodeling sigma(70) region 4
Embo J., 23, 2004
1KU7
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BU of 1ku7 by Molmil
Crystal Structure of Thermus aquatics RNA Polymerase SigmaA Subunit Region 4 Bound to-35 Element DNA
Descriptor: 5'-D(*CP*CP*TP*TP*GP*AP*CP*AP*AP*AP*G)-3', 5'-D(*CP*CP*TP*TP*TP*GP*TP*CP*AP*AP*G)-3', sigma factor sigA
Authors:Campbell, E.A, Muzzin, O, Chlenov, M, Sun, J.L, Olson, C.A, Weinman, O, Trester-Zedlitz, M.L, Darst, S.A.
Deposit date:2002-01-21
Release date:2002-03-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
1KU3
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BU of 1ku3 by Molmil
Crystal Structure of Thermus aquaticus RNA Polymerase Sigma Subunit Fragment, Region 4
Descriptor: sigma factor sigA
Authors:Campbell, E.A, Muzzin, O, Chlenov, M, Sun, J.L, Olson, C.A, Weinman, O, Trester-Zedlitz, M.L, Darst, S.A.
Deposit date:2002-01-21
Release date:2002-04-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
1NR3
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BU of 1nr3 by Molmil
SOLUTION STRUCTURE OF THE PROTEIN MTH0916: THE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT212
Descriptor: DNA-binding protein tfx
Authors:Shen, Y, Liu, G, Bhaskaran, R, Yee, A, Arrowsmith, C, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2003-01-23
Release date:2003-06-10
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:SOLUTION STRUCTURE OF THE PROTEIN MTH0916: THE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT212
To be Published
3HUG
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BU of 3hug by Molmil
Crystal structure of Mycobacterium tuberculosis anti-sigma factor RslA in complex with -35 promoter binding domain of sigL
Descriptor: PROBABLE CONSERVED MEMBRANE PROTEIN, RNA polymerase sigma factor, SULFATE ION, ...
Authors:Thakur, K.G, Gopal, B.
Deposit date:2009-06-14
Release date:2010-03-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and biochemical bases for the redox sensitivity of Mycobacterium tuberculosis RslA
J.Mol.Biol., 397, 2010
4G8X
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BU of 4g8x by Molmil
G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex
Descriptor: ORF067, RNA polymerase sigma factor rpoD
Authors:Darst, S.A, Osmundson, J.S, Montero-Diaz, C.M, Hochschild, A.
Deposit date:2012-07-23
Release date:2013-08-07
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein.
Cell(Cambridge,Mass.), 151, 2012
4G6D
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BU of 4g6d by Molmil
G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex
Descriptor: ORF067, RNA polymerase sigma factor rpoD
Authors:Darst, S.A, Osmundson, J.S.
Deposit date:2012-07-18
Release date:2013-01-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9971 Å)
Cite:Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein.
Cell(Cambridge,Mass.), 151, 2012
4G94
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BU of 4g94 by Molmil
G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex
Descriptor: ORF067, RNA polymerase sigma factor rpoD
Authors:Darst, S.A, Osmundson, J.S, Montero-Diaz, C.M, Hochschild, A.
Deposit date:2012-07-23
Release date:2013-01-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9971 Å)
Cite:Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein.
Cell(Cambridge,Mass.), 151, 2012
1TLH
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BU of 1tlh by Molmil
T4 AsiA bound to sigma70 region 4
Descriptor: 10 kDa anti-sigma factor, RNA polymerase sigma factor rpoD
Authors:Lambert, L.J, Wei, Y, Schirf, V, Demeler, B, Werner, M.H.
Deposit date:2004-06-09
Release date:2004-11-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:T4 AsiA blocks DNA recognition by remodeling sigma(70) region 4
Embo J., 23, 2004
8HNP
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BU of 8hnp by Molmil
Archaeal transcription factor Mutant
Descriptor: Archaeal transcription regulator
Authors:Bae, D.W, Cha, S.S.
Deposit date:2022-12-08
Release date:2023-09-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.39 Å)
Cite:An archaeal transcription factor EnfR with a novel 'eighth note' fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1.
Nucleic Acids Res., 51, 2023
8HNO
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BU of 8hno by Molmil
Archaeal transcription factor Wild type
Descriptor: Archaeal transcription regulator
Authors:Bae, D.W, Cha, S.S.
Deposit date:2022-12-08
Release date:2023-09-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:An archaeal transcription factor EnfR with a novel 'eighth note' fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1.
Nucleic Acids Res., 51, 2023
7RWI
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BU of 7rwi by Molmil
Mycobacterium tuberculosis RNA polymerase sigma L holoenzyme open promoter complex containing TNP-2198
Descriptor: (3aM,9S,10bP,14S,15R,16S,17R,18R,19R,20S,21S,25R)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl]-5,10,26-trioxo-3,5,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl acetate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Molodtsov, V, Ebright, R.H.
Deposit date:2021-08-19
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens.
J.Med.Chem., 65, 2022
2Z2S
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BU of 2z2s by Molmil
Crystal Structure of Rhodobacter sphaeroides SigE in complex with the anti-sigma ChrR
Descriptor: Anti-Sigma factor ChrR, transcriptional activator ChrR, RpoE, ...
Authors:Darst, S.A, Campbell, E.A.
Deposit date:2007-05-26
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria.
Mol.Cell, 27, 2007
3WOD
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BU of 3wod by Molmil
RNA polymerase-gp39 complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Tagami, S, Sekine, S, Minakhin, L, Esyunina, D, Akasaka, R, Shirouzu, M, Kulbachinskiy, A, Severinov, K, Yokoyama, S.
Deposit date:2013-12-26
Release date:2014-03-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for promoter specificity switching of RNA polymerase by a phage factor.
Genes Dev., 28, 2014
4Q4Z
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BU of 4q4z by Molmil
Thermus thermophilus RNA polymerase de novo transcription initiation complex
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ADENOSINE-5'-TRIPHOSPHATE, DNA (25-MER), ...
Authors:Murakami, K.S.
Deposit date:2014-04-15
Release date:2014-07-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of transcription initiation by bacterial RNA polymerase holoenzyme.
J.Biol.Chem., 289, 2014
7P5X
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BU of 7p5x by Molmil
Mycobacterial RNAP with transcriptional activator PafBC
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Mueller, A.U, Kummer, E, Schilling, C.M, Ban, N, Weber-Ban, E.
Deposit date:2021-07-15
Release date:2021-12-22
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Transcriptional control of mycobacterial DNA damage response by sigma adaptation.
Sci Adv, 7, 2021
3T72
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BU of 3t72 by Molmil
PhoB(E)-Sigma70(4)-(RNAP-Betha-flap-tip-helix)-DNA Transcription Activation Sub-Complex
Descriptor: PHO BOX DNA (STRAND 1), PHO BOX DNA (STRAND 2), Phosphate regulon transcriptional regulatory protein phoB, ...
Authors:Blanco, A.G, Canals, A, Bernues, J, Sola, M, Coll, M.
Deposit date:2011-07-29
Release date:2011-09-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (4.33 Å)
Cite:The structure of a transcription activation subcomplex reveals how sigma (70) is recruited to PhoB promoters.
Embo J., 30, 2011
8FTD
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BU of 8ftd by Molmil
Structure of Escherichia coli CedA in complex with transcription initiation complex
Descriptor: CHAPSO, Cell division activator CedA, DNA-directed RNA polymerase subunit alpha, ...
Authors:Liu, M, Vassyliev, N, Nudler, E.
Deposit date:2023-01-11
Release date:2024-01-10
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:General transcription factor from Escherichia coli with a distinct mechanism of action.
Nat.Struct.Mol.Biol., 31, 2024
2W48
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BU of 2w48 by Molmil
Crystal structure of the Full-length Sorbitol Operon Regulator SorC from Klebsiella pneumoniae
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ...
Authors:de Sanctis, D, McVey, C.E, Enguita, F.J, Carrondo, M.A.
Deposit date:2008-11-21
Release date:2009-05-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal Structure of the Full-Length Sorbitol Operon Regulator Sorc from Klebsiella Pneumoniae: Structural Evidence for a Novel Transcriptional Regulation Mechanism.
J.Mol.Biol., 387, 2009
3N97
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BU of 3n97 by Molmil
RNA polymerase alpha C-terminal domain (E. coli) and sigma region 4 (T. aq. mutant) bound to (UP,-35 element) DNA
Descriptor: ACETATE ION, DNA (5'-D(*CP*CP*AP*TP*GP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP*TP*TP*TP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*AP*AP*AP*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*CP*AP*TP*GP*G)-3'), ...
Authors:Lara-Gonzalez, S, Birktoft, J.J, Lawson, C.L.
Deposit date:2010-05-28
Release date:2011-06-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.252 Å)
Cite:The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element.
Biochemistry, 59, 2020
5TMF
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BU of 5tmf by Molmil
Re-refinement of thermus thermophilus RNA polymerase
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Wang, J.
Deposit date:2016-10-12
Release date:2016-11-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:On the validation of crystallographic symmetry and the quality of structures.
Protein Sci., 24, 2015
4LJZ
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BU of 4ljz by Molmil
Crystal Structure Analysis of the E.coli holoenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Bae, B, Darst, S.A.
Deposit date:2013-07-05
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.5871 Å)
Cite:Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
6EYD
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BU of 6eyd by Molmil
Structure of Mycobacterium smegmatis RNA polymerase Sigma-A holoenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Kouba, T, Barvik, I, Krasny, L.
Deposit date:2017-11-11
Release date:2018-12-12
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.22 Å)
Cite:The Core and Holoenzyme Forms of RNA Polymerase fromMycobacterium smegmatis.
J. Bacteriol., 201, 2019

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数据于2024-09-18公开中

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