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6SD6
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BU of 6sd6 by Molmil
Structure of VapBC from Shigella sonnei
Descriptor: Antitoxin, tRNA(fMet)-specific endonuclease VapC
Authors:Lea, S.M, Hollingshead, S.
Deposit date:2019-07-26
Release date:2020-08-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Polymorphisms in the VapBC toxin:antitoxin system mediate high frequency plasmid loss in Shigella sonnei
To Be Published
3TND
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BU of 3tnd by Molmil
Crystal structure of Shigella flexneri VapBC toxin-antitoxin complex
Descriptor: Antitoxin VapB, SODIUM ION, SULFATE ION, ...
Authors:Dienemann, C, Boggild, A, Winther, K.S, Gerdes, K, Brodersen, D.E.
Deposit date:2011-09-01
Release date:2011-11-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of the VapBC Toxin-Antitoxin Complex from Shigella flexneri Reveals a Hetero-Octameric DNA-Binding Assembly.
J.Mol.Biol., 414, 2011
7VWO
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BU of 7vwo by Molmil
TA complex from Mycobacterium tuberculosis
Descriptor: Antitoxin VapB43, Ribonuclease VapC43
Authors:Eun, H.-J, Lee, B.-J, Lee, J.-Y.
Deposit date:2021-11-11
Release date:2022-11-16
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:TA complex from Mycobacterium tuberculosis
To Be Published
5SV2
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BU of 5sv2 by Molmil
Toxin VapC21 from Mycobacterium tuberculosis
Descriptor: Ribonuclease VapC21
Authors:Valadares, N.F.
Deposit date:2016-08-04
Release date:2016-09-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Crystal structure of VapC21 from Mycobacterium tuberculosis at 1.31 angstrom resolution.
Biochem.Biophys.Res.Commun., 478, 2016
6IFM
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BU of 6ifm by Molmil
Crystal structure of DNA bound VapBC from Salmonella typhimurium
Descriptor: Antitoxin VapB, DNA backward (27-MER), DNA forward (27-MER), ...
Authors:Park, D.W, Lee, B.J.
Deposit date:2018-09-20
Release date:2020-01-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Crystal structure of proteolyzed VapBC and DNA-bound VapBC from Salmonella enterica Typhimurium LT2 and VapC as a putative Ca2+-dependent ribonuclease.
Faseb J., 34, 2020
6IFC
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BU of 6ifc by Molmil
Crystal structure of VapBC from Salmonella typhimurium
Descriptor: Antitoxin VapB, CALCIUM ION, tRNA(fMet)-specific endonuclease VapC
Authors:Park, D.W, Lee, B.J.
Deposit date:2018-09-19
Release date:2020-01-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal structure of proteolyzed VapBC and DNA-bound VapBC from Salmonella enterica Typhimurium LT2 and VapC as a putative Ca2+-dependent ribonuclease.
Faseb J., 34, 2020
1W8I
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BU of 1w8i by Molmil
The Structure of gene product af1683 from Archaeoglobus fulgidus.
Descriptor: PUTATIVE VAPC RIBONUCLEASE AF_1683
Authors:Midwest Center for Structural Genomics (MCSG), Cuff, M.E, Zhang, R, Ginell, S.L, Xu, X, Savchenko, A, Edwards, A, Joachimiak, A.
Deposit date:2004-09-22
Release date:2004-11-16
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structure of Gene Product Af1683 from Archaeoglobus Fulgidus
To be Published
5WZ4
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BU of 5wz4 by Molmil
Crystal structure of Mycobacterium tuberculosis VapC20 (Rv2549c), Sarcin-Ricin loop cleaving toxin
Descriptor: 23S rRNA-specific endonuclease VapC20
Authors:Thakur, K.G, Deep, A.
Deposit date:2017-01-17
Release date:2017-10-25
Last modified:2023-03-01
Method:X-RAY DIFFRACTION (1.775 Å)
Cite:Crystal structure of Mycobacterium tuberculosis VapC20 toxin and its interactions with cognate antitoxin, VapB20, suggest a model for toxin-antitoxin assembly.
FEBS J., 284, 2017
5WZF
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BU of 5wzf by Molmil
Crystal structure of Mycobacterium tuberculosis VapC20 (Rv2549c), Sarcin-Ricin loop cleaving toxin
Descriptor: 23S rRNA-specific endonuclease VapC20
Authors:Thakur, K.G, Deep, A.
Deposit date:2017-01-17
Release date:2017-10-25
Last modified:2023-03-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of Mycobacterium tuberculosis VapC20 toxin and its interactions with cognate antitoxin, VapB20, suggest a model for toxin-antitoxin assembly.
FEBS J., 284, 2017
1V8P
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BU of 1v8p by Molmil
Crystal structure of PAE2754 from Pyrobaculum aerophilum
Descriptor: CHLORIDE ION, hypothetical protein PAE2754
Authors:Arcus, V.L, Backbro, K, Roos, A, Daniel, E.L, Baker, E.N.
Deposit date:2004-01-12
Release date:2004-02-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Distant structural homology leads to the functional characterization of an archaeal PIN domain as an exonuclease
J.Biol.Chem., 279, 2004
1Y82
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BU of 1y82 by Molmil
Conserved hypothetical protein Pfu-367848-001 from Pyrococcus furiosus
Descriptor: UNKNOWN ATOM OR ION, hypothetical protein
Authors:Horanyi, P, Tempel, W, Habel, J, Chen, L, Lee, D, Nguyen, D, Chang, S.-H, Florence, Q, Zhou, W, Lin, D, Zhang, H, Praissman, J, Jenney Jr, F.E, Adams, M.W.W, Liu, Z.-J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-10
Release date:2005-01-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conserved hypothetical protein Pfu-367848-001 from Pyrococcus furiosus
To be published
1V8O
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BU of 1v8o by Molmil
Crystal Structure of PAE2754 from Pyrobaculum aerophilum
Descriptor: CHLORIDE ION, hypothetical protein PAE2754
Authors:Arcus, V.L, Backbro, K, Roos, A, Daniel, E.L, Baker, E.N.
Deposit date:2004-01-12
Release date:2004-02-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Distant structural homology leads to the functional characterization of an archaeal PIN domain as an exonuclease
J.Biol.Chem., 279, 2004
2H1C
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BU of 2h1c by Molmil
Crystal Structure of FitAcB from Neisseria gonorrhoeae
Descriptor: ACETATE ION, MAGNESIUM ION, SULFATE ION, ...
Authors:Mattison, K, Wilbur, J.S, So, M, Brennan, R.G.
Deposit date:2006-05-16
Release date:2006-09-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs.
J.Biol.Chem., 281, 2006
2FE1
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BU of 2fe1 by Molmil
Crystal Structure of PAE0151 from Pyrobaculum aerophilum
Descriptor: CALCIUM ION, CHLORIDE ION, MANGANESE (II) ION, ...
Authors:Bunker, R.D, Baker, E.N, Arcus, V.L.
Deposit date:2005-12-15
Release date:2005-12-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of PAE0151 from Pyrobaculum aerophilum, a PIN-domain (VapC) protein from a toxin-antitoxin operon.
Proteins, 72, 2008
5K8J
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BU of 5k8j by Molmil
Structure of Caulobacter crescentus VapBC1 (apo form)
Descriptor: GLYCEROL, Ribonuclease VapC, VapB family protein
Authors:Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
Deposit date:2016-05-30
Release date:2016-12-28
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
3IX7
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BU of 3ix7 by Molmil
Crystal structure of a domain of functionally unknown protein from Thermus thermophilus HB8
Descriptor: ACETIC ACID, Uncharacterized protein TTHA0540
Authors:Chang, C, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-09-03
Release date:2009-09-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of a domain of functionally unknown protein from Thermus thermophilus HB8
To be Published
3I8O
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BU of 3i8o by Molmil
A domain of a functionally unknown protein from Methanocaldococcus jannaschii DSM 2661.
Descriptor: ACETATE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Tan, K, Chhor, G, Cobb, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-07-09
Release date:2009-07-21
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.638 Å)
Cite:A domain of a functionally unknown protein from Methanocaldococcus jannaschii DSM 2661.
To be Published
5L6L
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BU of 5l6l by Molmil
Structure of Caulobacter crescentus VapBC1 bound to operator DNA
Descriptor: DNA (27-MER), Ribonuclease VapC, VapB family protein
Authors:Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
Deposit date:2016-05-30
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
5L6M
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BU of 5l6m by Molmil
Structure of Caulobacter crescentus VapBC1 (VapB1deltaC:VapC1 form)
Descriptor: GLYCEROL, MALONATE ION, Ribonuclease VapC, ...
Authors:Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
Deposit date:2016-05-30
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
5ECD
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BU of 5ecd by Molmil
Structure of the Shigella flexneri VapC mutant D98N crystal form 1
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, tRNA(fMet)-specific endonuclease VapC
Authors:Xu, K.
Deposit date:2015-10-20
Release date:2016-02-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri.
Proteins, 84, 2016
5ED0
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BU of 5ed0 by Molmil
Structure of the Shigella flexneri VapC mutant D7N
Descriptor: tRNA(fMet)-specific endonuclease VapC
Authors:Xu, K, Dedic, E, Brodersen, D.E.
Deposit date:2015-10-20
Release date:2016-02-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri.
Proteins, 84, 2016
5ECY
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BU of 5ecy by Molmil
Structure of the Shigella flexneri VapC mutant D98N crystal form 2
Descriptor: tRNA(fMet)-specific endonuclease VapC
Authors:Xu, K, Dedic, E, Brodersen, D.E.
Deposit date:2015-10-20
Release date:2016-10-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis on the active site architecture of an activated VapC toxin from Shigella flexneri
to be published
5ECW
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BU of 5ecw by Molmil
Structure of the Shigella flexneri VapC mutant D7A
Descriptor: tRNA(fMet)-specific endonuclease VapC
Authors:Xu, K, Dedic, E, Brodersen, D.E.
Deposit date:2015-10-20
Release date:2016-02-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri.
Proteins, 84, 2016
3DBO
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BU of 3dbo by Molmil
Crystal structure of a member of the VapBC family of toxin-antitoxin systems, VapBC-5, from Mycobacterium tuberculosis
Descriptor: ACETATE ION, BETA-MERCAPTOETHANOL, SODIUM ION, ...
Authors:Miallau, L, Cascio, D, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC)
Deposit date:2008-06-02
Release date:2008-07-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structure and Proposed Activity of a Member of the VapBC Family of Toxin-Antitoxin Systems: VapBC-5 FROM MYCOBACTERIUM TUBERCULOSIS.
J.Biol.Chem., 284, 2009
6NKL
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BU of 6nkl by Molmil
2.2 A resolution structure of VapBC-1 from nontypeable Haemophilus influenzae
Descriptor: Antitoxin VapB1, Ribonuclease VapC
Authors:Lovell, S, Kashipathy, M.M, Battaile, K.P, Molinaro, A.L, Daines, D.A.
Deposit date:2019-01-07
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of VapBC-1 from Nontypeable Haemophilus influenzae and the Effect of PIN Domain Mutations on Survival during Infection.
J.Bacteriol., 201, 2019

 

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