7POG
 
 | | High-resolution structure of native toxin A from Clostridioides difficile | | 分子名称: | Toxin A, ZINC ION | | 著者 | Boesen, T, Joergensen, R, Aminzadeh, A, Engelbrecht Larsen, C. | | 登録日 | 2021-09-08 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | | 主引用文献 | High-resolution structure of native toxin A from Clostridioides difficile.
Embo Rep., 23, 2022
|
|
8JHZ
 | |
4R04
 | |
8JB5
 | |
6AR6
 | |
7S0Y
 | | Structures of TcdB in complex with Cdc42 | | 分子名称: | Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Zheng, L, Rongsheng, J, Peng, C. | | 登録日 | 2021-08-31 | | 公開日 | 2021-09-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B.
Sci Adv, 7, 2021
|
|
7S0Z
 | | Structures of TcdB in complex with R-Ras | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, AMMONIUM ION, ... | | 著者 | Zheng, L, Rongsheng, J, Peng, C. | | 登録日 | 2021-08-31 | | 公開日 | 2021-09-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B.
Sci Adv, 7, 2021
|
|
3SS1
 | | Clostridium difficile toxin A (TcdA) glucolsyltransferase domain | | 分子名称: | MANGANESE (II) ION, Toxin A | | 著者 | Pruitt, R.N, Chumbler, N.M, Farrow, M.A, Seeback, S.A, Friedman, D.B, Spiller, B.W, Lacy, D.B. | | 登録日 | 2011-07-07 | | 公開日 | 2012-02-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Structural Determinants of Clostridium difficile Toxin A Glucosyltransferase Activity.
J.Biol.Chem., 287, 2012
|
|
8QEO
 | |
8QEN
 | |
4DMW
 | | Crystal structure of the GT domain of Clostridium difficile toxin A (TcdA) in complex with UDP and Manganese | | 分子名称: | MANGANESE (II) ION, Toxin A, URIDINE-5'-DIPHOSPHATE | | 著者 | Malito, E, D'Urzo, N, Bottomley, M.J, Biancucci, M, Scarselli, M, Maione, D, Martinelli, M. | | 登録日 | 2012-02-08 | | 公開日 | 2012-07-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structure of Clostridium difficile toxin A glucosyltransferase domain bound to Mn2+ and UDP provides insights into glucosyltransferase activity and product release.
Febs J., 279, 2012
|
|
4DMV
 | | Crystal structure of the GT domain of Clostridium difficile Toxin A | | 分子名称: | Toxin A | | 著者 | Malito, E, D'Urzo, N, Bottomley, M.J, Biancucci, M, Maione, D, Scarselli, M, Martinelli, M. | | 登録日 | 2012-02-08 | | 公開日 | 2012-07-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The structure of Clostridium difficile toxin A glucosyltransferase domain bound to Mn2+ and UDP provides insights into glucosyltransferase activity and product release.
Febs J., 279, 2012
|
|
2BVL
 | | Crystal structure of the catalytic domain of toxin B from Clostridium difficile in complex with UDP, Glc and manganese ion | | 分子名称: | HEXATANTALUM DODECABROMIDE, MANGANESE (II) ION, SULFATE ION, ... | | 著者 | Reinert, D.J, Jank, T, Aktories, K, Schulz, G.E. | | 登録日 | 2005-06-30 | | 公開日 | 2005-08-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis for the Function of Clostridium Difficile Toxin B.
J.Mol.Biol., 351, 2005
|
|
2BVM
 | | Crystal structure of the catalytic domain of toxin B from Clostridium difficile in complex with UDP, Glc and manganese ion | | 分子名称: | MANGANESE (II) ION, SULFATE ION, TOXIN B, ... | | 著者 | Reinert, D.J, Jank, T, Aktories, K, Schulz, G.E. | | 登録日 | 2005-06-30 | | 公開日 | 2005-08-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural Basis for the Function of Clostridium Difficile Toxin B.
J.Mol.Biol., 351, 2005
|
|
3SRZ
 | | Clostridium difficile toxin A (TcdA) glucolsyltransferase domain bound to UDP-glucose | | 分子名称: | MANGANESE (II) ION, Toxin A, URIDINE-5'-DIPHOSPHATE-GLUCOSE | | 著者 | Pruitt, R.N, Chumbler, N.M, Farrow, M.A, Seeback, S.A, Friedman, D.B, Spiller, B.W, Lacy, D.B. | | 登録日 | 2011-07-07 | | 公開日 | 2012-02-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Structural Determinants of Clostridium difficile Toxin A Glucosyltransferase Activity.
J.Biol.Chem., 287, 2012
|
|
6OQ5
 | | Structure of the full-length Clostridium difficile toxin B in complex with 3 VHHs | | 分子名称: | 5D, 7F, E3, ... | | 著者 | Chen, P, Lam, K, Jin, R. | | 登録日 | 2019-04-25 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.87 Å) | | 主引用文献 | Structure of the full-length Clostridium difficile toxin B.
Nat.Struct.Mol.Biol., 26, 2019
|
|
6OQ7
 | | Structure of the GTD domain of Clostridium difficile toxin B in complex with VHH E3 | | 分子名称: | E3, MAGNESIUM ION, MANGANESE (II) ION, ... | | 著者 | Chen, P, Lam, K, Jin, R. | | 登録日 | 2019-04-25 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Structure of the full-length Clostridium difficile toxin B.
Nat.Struct.Mol.Biol., 26, 2019
|
|
6OQ8
 | |
8X2I
 | |
8X2H
 | |
8Y9B
 | |
2VKD
 | | CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF LETHAL TOXIN FROM CLOSTRIDIUM SORDELLII IN COMPLEX WITH UDP-GLC AND MANGANESE ION | | 分子名称: | CYTOTOXIN L, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE-GLUCOSE | | 著者 | Ziegler, M.O.P, Jank, T, Aktories, K, Schulz, G.E. | | 登録日 | 2007-12-18 | | 公開日 | 2008-03-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Conformational Changes and Reaction of Clostridial Glycosylating Toxins.
J.Mol.Biol., 377, 2008
|
|
2VL8
 | | CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF LETHAL TOXIN FROM CLOSTRIDIUM SORDELLII IN COMPLEX WITH UDP, CASTANOSPERMINE AND CALCIUM ION | | 分子名称: | CALCIUM ION, CASTANOSPERMINE, CYTOTOXIN L, ... | | 著者 | Jank, T, Ziegler, M.O.P, Schulz, G.E, Aktories, K. | | 登録日 | 2008-01-09 | | 公開日 | 2008-06-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Inhibition of the Glucosyltransferase Activity of Clostridial Rho/Ras-Glucosylating Toxins by Castanospermine.
FEBS Lett., 582, 2008
|
|
2VK9
 | |
2VKH
 | | CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF LETHAL TOXIN FROM CLOSTRIDIUM SORDELLII IN COMPLEX WITH UDP-GLC AND CALCIUM ION | | 分子名称: | CALCIUM ION, CYTOTOXIN L, URIDINE-5'-DIPHOSPHATE-GLUCOSE | | 著者 | Ziegler, M.O.P, Jank, T, Aktories, K, Schulz, G.E. | | 登録日 | 2007-12-19 | | 公開日 | 2008-03-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Conformational Changes and Reaction of Clostridial Glycosylating Toxins.
J.Mol.Biol., 377, 2008
|
|
