PDB: 11 件ウェブページステータス検索Chemie searchBIRD

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5I35	Structure of the Human mitochondrial kinase COQ8A R611K with AMPPNP (Cerebellar Ataxia and Ubiquinone Deficiency Through Loss of Unorthodox Kinase Activity) 分子名称: Atypical kinase ADCK3, mitochondrial, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Bingman, C.A, Stefely, J.A, Pagliarini, D.J, Mitochondrial Protein Partnership (MPP) 登録日 2016-02-09 公開日 2016-08-17 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity. Mol.Cell, 63, 2016
4PED	Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthes 分子名称: Chaperone activity of bc1 complex-like, mitochondrial, SULFATE ION 著者 Bingman, C.A, Smith, R, Joshi, S, Stefely, J.A, Reidenbach, A.G, Ulbrich, A, Oruganty, O, Floyd, B.J, Jochem, A, Saunders, J.M, Johnson, I.E, Wrobel, R.L, Barber, G.E, Lee, D, Li, S, Kannan, N, Coon, J.J, Pagliarini, D.J, Mitochondrial Protein Partnership (MPP) 登録日 2014-04-22 公開日 2014-11-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Mitochondrial ADCK3 Employs an Atypical Protein Kinase-like Fold to Enable Coenzyme Q Biosynthesis. Mol.Cell, 57, 2015
7UDQ	Crystal structure of COQ8A-CA157 inhibitor complex in space group P1 分子名称: 4-[(3,4,5-trimethoxyphenyl)amino]quinoline-7-carbonitrile, Atypical kinase COQ8A, mitochondrial, ... 著者 Bingman, C.A, Murray, N, Smith, R.W, Pagliarini, D.J. 登録日 2022-03-20 公開日 2023-01-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Small-molecule inhibition of the archetypal UbiB protein COQ8. Nat.Chem.Biol., 19, 2023
7UDP	Crystal structure of COQ8A-CA157 inhibitor complex in space group C2 分子名称: 4-[(3,4,5-trimethoxyphenyl)amino]quinoline-7-carbonitrile, Atypical kinase COQ8A, mitochondrial 著者 Bingman, C.A, Murray, N, Smith, R.W, Pagliarini, D.J. 登録日 2022-03-20 公開日 2023-01-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Small-molecule inhibition of the archetypal UbiB protein COQ8. Nat.Chem.Biol., 19, 2023
7CY2	The open conformation of MSMEG_1954 from Mycobacterium smegmatis 分子名称: ABC1 family protein, SULFATE ION 著者 Zhang, Q, Rao, Z.H. 登録日 2020-09-03 公開日 2021-12-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Conformational Changes in a Macrolide Antibiotic Binding Protein From Mycobacterium smegmatis Upon ADP Binding. Front Microbiol, 12, 2021
7CZ2	The complex structure of MSMEG_1954-ADP from Mycobacterium smegmatis 分子名称: ABC1 family protein, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... 著者 Zhang, Q, Rao, Z.H. 登録日 2020-09-07 公開日 2021-12-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Conformational Changes in a Macrolide Antibiotic Binding Protein From Mycobacterium smegmatis Upon ADP Binding. Front Microbiol, 12, 2021
7CYR	The closed conformation of MSMEG_1954 from Mycobacterium smegmatis 分子名称: ABC1 family protein, ACETATE ION 著者 Zhang, Q, Rao, Z.H. 登録日 2020-09-04 公開日 2021-12-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Conformational Changes in a Macrolide Antibiotic Binding Protein From Mycobacterium smegmatis Upon ADP Binding. Front Microbiol, 12, 2021
5YJZ	The native crystal structure of Rv3197 from Mycobacterium tuberculosis 分子名称: GLYCEROL, Probable conserved ATP-binding protein ABC transporter, SULFATE ION 著者 Zhang, Q.Q, Rao, Z.H. 登録日 2017-10-11 公開日 2018-02-07 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target. Protein Cell, 9, 2018
5YK2	The complex structure of Rv3197-erythromycin from Mycobacterium tuberculosis 分子名称: ERYTHROMYCIN A, Probable conserved ATP-binding protein ABC transporter 著者 Rao, Z.H, Zhang, Q.Q. 登録日 2017-10-11 公開日 2018-02-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.807 Å) 主引用文献 Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target. Protein Cell, 9, 2018
5YK0	The complex structure of Rv3197-ADP from Mycobacterium tuberculosis 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Probable conserved ATP-binding protein ABC transporter, ... 著者 Rao, Z.H, Zhang, Q.Q. 登録日 2017-10-11 公開日 2018-02-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target. Protein Cell, 9, 2018
5YK1	The complex structure of Rv3197-AMPPNP from Mycobacterium tuberculosis 分子名称: GLYCEROL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Probable conserved ATP-binding protein ABC transporter, ... 著者 Rao, Z.H, Zhang, Q.Q. 登録日 2017-10-11 公開日 2018-02-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.103 Å) 主引用文献 Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target. Protein Cell, 9, 2018