5YK2

The complex structure of Rv3197-erythromycin from Mycobacterium tuberculosis

Summary for 5YK2

Entry DOI	10.2210/pdb5yk2/pdb
Descriptor	Probable conserved ATP-binding protein ABC transporter, ERYTHROMYCIN A (2 entities in total)
Functional Keywords	mycobacterium tuberculosis, macrolide antibiotic binding protein, non-canonical abc protein, transport protein
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains	1
Total formula weight	50333.21
Authors	Rao, Z.H.,Zhang, Q.Q. (deposition date: 2017-10-11, release date: 2018-02-07, Last modification date: 2023-11-22)
Primary citation	Zhang, Q.,Liu, H.,Liu, X.,Jiang, D.,Zhang, B.,Tian, H.,Yang, C.,Guddat, L.W.,Yang, H.,Mi, K.,Rao, Z. Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target. Protein Cell, 9:971-975, 2018 Cited by PubMed: 29350349 DOI: 10.1007/s13238-017-0502-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.807 Å)

Structure validation