3KDP
| Crystal structure of the sodium-potassium pump | 分子名称: | CHOLESTEROL, MAGNESIUM ION, Na+/K+ ATPase gamma subunit transcript variant a, ... | 著者 | Morth, J.P, Pedersen, B.P, Nissen, P. | 登録日 | 2009-10-23 | 公開日 | 2010-02-16 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structure of the sodium-potassium pump. Nature, 450, 2007
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4UX2
| Cryo-EM structure of antagonist-bound E2P gastric H,K-ATPase (SCH.E2. MgF) | 分子名称: | POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA | 著者 | Abe, K, Tani, K, Fujiyoshi, Y. | 登録日 | 2014-08-18 | 公開日 | 2014-09-17 | 最終更新日 | 2014-11-12 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (7 Å) | 主引用文献 | Systematic Comparison of Molecular Conformations of H+,K+-ATPase Reveals an Important Contribution of the A-M2 Linker for the Luminal Gating. J.Biol.Chem., 289, 2014
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5MPM
| SERCA2a from pig heart | 分子名称: | (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Drachmann, N.D, Sitsel, A, Andersen, J.L, Nissen, P, Olesen, C. | 登録日 | 2016-12-16 | 公開日 | 2018-01-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structures of the heart specific SERCA2a Ca2+-ATPase. Embo J., 38, 2019
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2XZB
| Pig Gastric H,K-ATPase with bound BeF and SCH28080 | 分子名称: | POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA | 著者 | Abe, K, Tani, K, Fujiyoshi, Y. | 登録日 | 2010-11-24 | 公開日 | 2011-01-26 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (7 Å) | 主引用文献 | Conformational Rearrangement of Gastric H(+),K(+)- ATPase Induced by an Acid Suppressant. Nat.Commun., 2, 2011
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7QTV
| Beryllium fluoride form of the Na+,K+-ATPase (E2-BeFx) | 分子名称: | 1-O-decanoyl-beta-D-tagatofuranosyl beta-D-allopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Fruergaard, M.U, Dach, I, Andersen, J.L, Ozol, M, Shahsavar, A, Quistgaard, E.M, Poulsen, H, Fedosova, N.U, Nissen, P. | 登録日 | 2022-01-16 | 公開日 | 2022-11-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (4.05 Å) | 主引用文献 | The Na + ,K + -ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state. J.Biol.Chem., 298, 2022
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6RB2
| Structure of the (SR)Ca2+-ATPase mutant E340A in the Ca2-E1-CaAMPPCP form | 分子名称: | CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... | 著者 | Clausen, J.D, Montigny, C, Lenoir, G, Arnou, B, Jaxel, C, Moller, J.V, Nissen, P, Andersen, J.P, Le Maire, M, Bublitz, M. | 登録日 | 2019-04-09 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.20001125 Å) | 主引用文献 | The SERCA residue Glu340 mediates interdomain communication that guides Ca 2+ transport. Proc.Natl.Acad.Sci.USA, 117, 2020
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4NAB
| Structure of the (SR)Ca2+-ATPase mutant E309Q in the Ca2-E1-MgAMPPCP form | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, POTASSIUM ION, ... | 著者 | Bublitz, M, Clausen, J.D, Arnou, B, Montigny, C, Jaxel, C, Nissen, P, Moller, J.V, Andersen, J.P, le Maire, M. | 登録日 | 2013-10-22 | 公開日 | 2013-12-18 | 最終更新日 | 2017-08-09 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | SERCA mutant E309Q binds two Ca(2+) ions but adopts a catalytically incompetent conformation. Embo J., 32, 2013
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6YAA
| Structure of the (SR) Ca2+-ATPase bound to the inhibitor compound CAD204520 and TNP-ATP | 分子名称: | 4-[2-[(2~{R})-2-[3-propyl-6-(trifluoromethyloxy)-1~{H}-indol-2-yl]piperidin-1-yl]ethyl]morpholine, POTASSIUM ION, SPIRO(2,4,6-TRINITROBENZENE[1,2A]-2O',3O'-METHYLENE-ADENINE-TRIPHOSPHATE, ... | 著者 | Heit, S, Marchesini, M, Gherli, A, Montanaro, A, Patrizi, L, Sorrentino, C, Pagliaro, L, Rompietti, C, Kitara, S, Olesen, C.E, Moller, J.V, Savi, M, Bocchi, L, Vilella, R, Rizzi, F, Baglione, M, Rastelli, G, Loiacona, C, La Starza, R, Mecucci, C, Stegmair, K, Aversa, F, Stilli, D, Lund Winther, A.M, Sportoletti, P, Dalby-Brown, W, Roti, G, Bublitz, M. | 登録日 | 2020-03-11 | 公開日 | 2020-05-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia. Cell Chem Biol, 27, 2020
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5NCQ
| Structure of the (SR) Ca2+-ATPase bound to a Tetrahydrocarbazole and TNP-ATP | 分子名称: | (1~{S})-~{N}-[(4-bromophenyl)methyl]-7-(trifluoromethyloxy)-2,3,4,9-tetrahydro-1~{H}-carbazol-1-amine, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, POTASSIUM ION, ... | 著者 | Bublitz, M, Kjellerup, L, O'Hanlon Cohrt, K, Gordon, S, Mortensen, A.L, Clausen, J.D, Pallin, D, Hansen, J.B, Brown, W.D, Fuglsang, A, Winther, A.-M.L. | 登録日 | 2017-03-06 | 公開日 | 2018-01-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Tetrahydrocarbazoles are a novel class of potent P-type ATPase inhibitors with antifungal activity. PLoS ONE, 13, 2018
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8WA5
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4H1W
| E1 structure of the (SR) Ca2+-ATPase in complex with Sarcolipin | 分子名称: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... | 著者 | Bublitz, M, Winther, A.-M.L, Karlsen, J, Moller, J.V, Hansen, J.B, Buch-Pedersen, M.J, Nissen, P. | 登録日 | 2012-09-11 | 公開日 | 2013-03-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm. Nature, 495, 2013
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4UU1
| CRYSTAL STRUCTURE OF (SR) CALCIUM-ATPASE E2(TG) IN THE PRESENCE OF DOPC | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Drachmann, N.D, Olesen, C, Moeller, J.V, Guo, Z, Nissen, P, Bublitz, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Comparing Crystal Structures of Ca(2+) -ATPase in the Presence of Different Lipids. FEBS J., 281, 2014
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4XE5
| Crystal structure of the Na,K-ATPase from bovine | 分子名称: | CHOLESTEROL, MAGNESIUM ION, OUABAIN, ... | 著者 | Gregersen, J.L, Mattle, D, Fedosova, N.U, Nissen, P, Reinhard, L. | 登録日 | 2014-12-22 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.901 Å) | 主引用文献 | Isolation, crystallization and crystal structure determination of bovine kidney Na(+),K(+)-ATPase. Acta Crystallogr.,Sect.F, 72, 2016
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4UU0
| CRYSTAL STRUCTURE OF (SR) CALCIUM-ATPASE E2(TG) IN THE PRESENCE OF 14:1 PC | 分子名称: | GLYCEROL, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | 著者 | Drachmann, N.D, Olesen, C, Moeller, J.V, Guo, Z, Nissen, P, Bublitz, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Comparing Crystal Structures of Ca(2+) -ATPase in the Presence of Different Lipids. FEBS J., 281, 2014
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4UX1
| Cryo-EM structure of antagonist-bound E2P gastric H,K-ATPase (SCH.E2. AlF) | 分子名称: | POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA | 著者 | Abe, K, Tani, K, Fujiyoshi, Y. | 登録日 | 2014-08-18 | 公開日 | 2014-09-17 | 最終更新日 | 2014-11-12 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (8 Å) | 主引用文献 | Systematic Comparison of Molecular Conformations of H+,K+-ATPase Reveals an Important Contribution of the A-M2 Linker for the Luminal Gating. J.Biol.Chem., 289, 2014
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4YCL
| Crystal structure of the SR CA2+-ATPASE with bound CPA | 分子名称: | (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Ogawa, H, Takahashi, M, Kondou, Y, Toyoshima, C. | 登録日 | 2015-02-20 | 公開日 | 2015-04-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors Proc.Natl.Acad.Sci.Usa, 104, 2007
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4RET
| Crystal structure of the Na,K-ATPase E2P-digoxin complex with bound magnesium | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Gregersen, J.L, Laursen, M, Yatime, L, Nissen, P, Fedosova, N.U. | 登録日 | 2014-09-23 | 公開日 | 2015-01-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complex. Proc.Natl.Acad.Sci.USA, 112, 2015
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4RES
| Crystal structure of the Na,K-ATPase E2P-bufalin complex with bound potassium | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Laursen, M, Yatime, L, Gregersen, J.L, Nissen, P, Fedosova, N.U. | 登録日 | 2014-09-23 | 公開日 | 2015-01-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.408 Å) | 主引用文献 | Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complex. Proc.Natl.Acad.Sci.USA, 112, 2015
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3IXZ
| Pig gastric H+/K+-ATPase complexed with aluminium fluoride | 分子名称: | Potassium-transporting ATPase alpha, Potassium-transporting ATPase subunit beta | 著者 | Abe, K, Tani, K, Nishizawa, T, Fujiyoshi, Y. | 登録日 | 2009-03-09 | 公開日 | 2009-06-23 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (6.5 Å) | 主引用文献 | Inter-subunit interaction of gastric H+,K+-ATPase prevents reverse reaction of the transport cycle Embo J., 28, 2009
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4XOU
| Crystal structure of the SR Ca2+-ATPase in the Ca2-E1-MgAMPPCP form determined by serial femtosecond crystallography using an X-ray free-electron laser. | 分子名称: | CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... | 著者 | Bublitz, M, Nass, K, Drachmann, N.D, Markvardsen, A.J, Gutmann, M.J, Barends, T.R.M, Mattle, D, Shoeman, R.L, Doak, R.B, Boutet, S, Messerschmidt, M, Seibert, M.M, Williams, G.J, Foucar, L, Reinhard, L, Sitsel, O, Gregersen, J.L, Clausen, J.D, Boesen, T, Gotfryd, K, Wang, K.-T, Olesen, C, Moller, J.V, Nissen, P, Schlichting, I. | 登録日 | 2015-01-16 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural studies of P-type ATPase-ligand complexes using an X-ray free-electron laser. Iucrj, 2, 2015
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6HXB
| SERCA2a from pig heart | 分子名称: | CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... | 著者 | Sitsel, A, Andersen, J.L, Nissen, P, Olesen, C. | 登録日 | 2018-10-16 | 公開日 | 2019-02-27 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structures of the heart specific SERCA2a Ca 2+ -ATPase. Embo J., 38, 2019
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2O9J
| Crystal structure of calcium atpase with bound magnesium fluoride and cyclopiazonic acid | 分子名称: | (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, MAGNESIUM ION, SODIUM ION, ... | 著者 | Young, H.S, Moncoq, K.A. | 登録日 | 2006-12-13 | 公開日 | 2007-02-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | The molecular basis for cyclopiazonic Acid inhibition of the sarcoplasmic reticulum calcium pump. J.Biol.Chem., 282, 2007
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2OA0
| Crystal structure of Calcium ATPase with bound ADP and cyclopiazonic acid | 分子名称: | (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Young, H.S, Moncoq, K.A. | 登録日 | 2006-12-14 | 公開日 | 2007-02-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | The molecular basis for cyclopiazonic Acid inhibition of the sarcoplasmic reticulum calcium pump. J.Biol.Chem., 282, 2007
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6HEF
| Room temperature structure of the (SR)Ca2+-ATPase Ca2-E1-CaAMPPCP form | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Hjorth-Jensen, S, Sorensen, T.L.M, Oksanen, E, Andersen, J.L, Olesen, C, Moller, J.V, Nissen, P. | 登録日 | 2018-08-20 | 公開日 | 2018-08-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.538 Å) | 主引用文献 | Membrane-protein crystals for neutron diffraction. Acta Crystallogr D Struct Biol, 74, 2018
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1KJU
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