2OA0
Crystal structure of Calcium ATPase with bound ADP and cyclopiazonic acid
Summary for 2OA0
| Entry DOI | 10.2210/pdb2oa0/pdb |
| Related | 2O9J |
| Descriptor | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, MAGNESIUM ION, (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, ... (4 entities in total) |
| Functional Keywords | calcium atpase, serca, mycotoxin, cyclopiazonic acid, hydrolase |
| Biological source | Oryctolagus cuniculus (rabbit) |
| Cellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein : P04191 |
| Total number of polymer chains | 1 |
| Total formula weight | 110390.47 |
| Authors | Young, H.S.,Moncoq, K.A. (deposition date: 2006-12-14, release date: 2007-02-06, Last modification date: 2023-08-30) |
| Primary citation | Moncoq, K.,Trieber, C.A.,Young, H.S. The molecular basis for cyclopiazonic Acid inhibition of the sarcoplasmic reticulum calcium pump. J.Biol.Chem., 282:9748-9757, 2007 Cited by PubMed: 17259168DOI: 10.1074/jbc.M611653200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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