7P0J
| Crystal structure of S.pombe Mdb1 BRCT domains | 分子名称: | CITRIC ACID, DNA damage response protein Mdb1, MAGNESIUM ION, ... | 著者 | Day, M, Oliver, A.W, Pearl, L.H. | 登録日 | 2021-06-29 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Phosphorylation-dependent assembly of DNA damage response systems and the central roles of TOPBP1. DNA Repair (Amst), 108, 2021
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4U4A
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1N5O
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1CDZ
| BRCT DOMAIN FROM DNA-REPAIR PROTEIN XRCC1 | 分子名称: | PROTEIN (DNA-REPAIR PROTEIN XRCC1) | 著者 | Zhang, X, Morera, S, Bates, P, Whitehead, P, Coffer, A, Hainbucher, K, Nash, R, Sternberg, M, Lindahl, T, Freemont, P. | 登録日 | 1999-03-04 | 公開日 | 2000-02-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of an XRCC1 BRCT domain: a new protein-protein interaction module. EMBO J., 17, 1998
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6RML
| Crystal structure of TOPBP1 BRCT0,1,2 in complex with a 53BP1 phosphopeptide | 分子名称: | 53BP1, DNA topoisomerase 2-binding protein 1 | 著者 | Day, M, Oliver, A.W, Pearl, L.H. | 登録日 | 2019-05-07 | 公開日 | 2019-06-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint. Elife, 8, 2019
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6RMM
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7CMZ
| Crystal Structure of BRCT7/8 in Complex with the APS Motif of PHF8 | 分子名称: | DNA topoisomerase 2-binding protein 1, Histone lysine demethylase PHF8, POTASSIUM ION, ... | 著者 | Che, S.Y, Ma, S, Cao, C, Yao, Z, Shi, L, Yang, N. | 登録日 | 2020-07-29 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.695 Å) | 主引用文献 | PHF8-promoted TOPBP1 demethylation drives ATR activation and preserves genome stability. Sci Adv, 7, 2021
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1OQA
| Solution structure of the BRCT-c domain from human BRCA1 | 分子名称: | Breast cancer type 1 susceptibility protein | 著者 | Gaiser, O.J, Ball, L.J, Schmieder, P, Leitner, D, Strauss, H, Wahl, M, Kuhne, R, Oschkinat, H, Heinemann, U. | 登録日 | 2003-03-07 | 公開日 | 2004-06-15 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1. Biochemistry, 43, 2004
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6WH2
| Structure of the C-terminal BRCT domain of human XRCC1 | 分子名称: | X-ray repair cross complementing protein 1 variant | 著者 | Pourfarjam, Y, Ellenberger, T, Tainer, J.A, Tomkinson, A.E, Kim, I.K. | 登録日 | 2020-04-07 | 公開日 | 2020-12-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.414 Å) | 主引用文献 | An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase III alpha within a flexible DNA repair complex. Nucleic Acids Res., 49, 2021
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4OFB
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4Y18
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4Y2G
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1JNX
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3UEN
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3UEO
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4IGK
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2ING
| X-ray Structure of the BRCA1 BRCT mutant M1775K | 分子名称: | Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION | 著者 | Birrane, G, Soni, A, Ladias, J.A.A. | 登録日 | 2006-10-07 | 公開日 | 2007-09-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach. Eur.J.Hum.Genet., 16, 2008
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4IFI
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1L0B
| Crystal Structure of rat Brca1 tandem-BRCT region | 分子名称: | BRCA1 | 著者 | Joo, W.S, Jeffrey, P.D, Cantor, S.B, Finnin, M.S, Livingston, D.M, Pavletich, N.P. | 登録日 | 2002-02-08 | 公開日 | 2002-03-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev., 16, 2002
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1L7B
| Solution NMR Structure of BRCT Domain of T. Thermophilus: Northeast Structural Genomics Consortium Target WR64TT | 分子名称: | DNA LIGASE | 著者 | Sahota, G, Dixon, B.L, Huang, Y.P, Aramini, J, Monleon, D, Bhattacharya, D, Swapna, G.V.T, Yin, C, Xiao, R, Anderson, S, Tejero, R, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2002-03-14 | 公開日 | 2003-09-16 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of the Brct Domain from Thermus Thermophilus DNA Ligase To be Published
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4JLU
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2K7F
| HADDOCK calculated model of the complex between the BRCT region of RFC p140 and dsDNA | 分子名称: | 5'-D(P*DCP*DGP*DAP*DCP*DCP*DTP*DCP*DGP*DAP*DGP*DAP*DTP*DCP*DA)-3', 5'-D(P*DCP*DTP*DCP*DGP*DAP*DGP*DGP*DTP*DCP*DG)-3', Replication factor C subunit 1 | 著者 | Kobayashi, M, Ab, E, Bonvin, A, Siegal, G. | 登録日 | 2008-08-10 | 公開日 | 2009-09-08 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the DNA-bound BRCA1 C-terminal region from human replication factor C p140 and model of the protein-DNA complex. J.Biol.Chem., 285, 2010
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2K6G
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2LE0
| PARP BRCT Domain | 分子名称: | Poly [ADP-ribose] polymerase 1 | 著者 | Mueller, G, Loeffler, P, Cuneo, M, Derose, E, London, R. | 登録日 | 2011-06-03 | 公開日 | 2011-10-19 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural studies of the PARP-1 BRCT domain. Bmc Struct.Biol., 11, 2011
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3AL2
| Crystal Structure of TopBP1 BRCT7/8 | 分子名称: | DNA topoisomerase 2-binding protein 1, SULFATE ION | 著者 | Leung, C.C, Glover, J.N. | 登録日 | 2010-07-22 | 公開日 | 2010-12-01 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control J.Biol.Chem., 286, 2011
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