PDB: 13 件ウェブページステータス検索Chemie searchBIRD

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6AXJ	Crystal structure of the Yaf9 YEATS domain bound to H3K27ac 分子名称: ALY-SER-ALA-PRO-ALA, GLYCEROL, Protein AF-9 homolog, ... 著者 Klein, B.J, Kutateladze, T.G. 登録日 2017-09-06 公開日 2017-11-22 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (2.379 Å) 主引用文献 Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain. Nucleic Acids Res., 46, 2018
5J9S	ENL YEATS in complex with histone H3 acetylation at K27 分子名称: H3K27ac peptide from Histone H3.1, Protein ENL, SULFATE ION 著者 Li, Y, Li, H. 登録日 2016-04-11 公開日 2017-03-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.702 Å) 主引用文献 ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia Nature, 543, 2017
5XNV	Crystal structure of YEATS2 YEATS bound to H3K27ac peptide 分子名称: ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, AMMONIUM ION, CHLORIDE ION, ... 著者 Li, H.T, Guan, H.P, Zhao, D. 登録日 2017-05-24 公開日 2017-11-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.696 Å) 主引用文献 YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer. Nat Commun, 8, 2017
5XTZ	Crystal structure of GAS41 YEATS bound to H3K27ac peptide 分子名称: ACETATE ION, THR-LYS-ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, YEATS domain-containing protein 4 著者 Li, H.T, Zhao, D. 登録日 2017-06-21 公開日 2018-06-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.105 Å) 主引用文献 Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity. Cell Discov, 4, 2018
7X8G	Crystal structure of ENL T1(H116P) mutant YEATS domain in complex with histone H3 acetylation at K27 分子名称: H3K27ac(24-27) peptide, Protein ENL 著者 Li, Y, Peng, B, Li, H. 登録日 2022-03-12 公開日 2023-01-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. Mol.Cell, 82, 2022
7X8B	Crystal structure of ENL T1 mutant YEATS domain in complex with histone H3 acetylation at K27 分子名称: H3K27ac(24-27) peptide, Protein ENL 著者 Li, Y, Peng, B, Li, H. 登録日 2022-03-11 公開日 2023-01-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. Mol.Cell, 82, 2022
8IIZ	Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K27ac peptide 分子名称: GLYCEROL, Histone H3.1, Maltodextrin-binding protein,YEATS domain-containing protein 4, ... 著者 Kikuchi, M, Umehara, T. 登録日 2023-02-24 公開日 2023-11-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain. Proc.Natl.Acad.Sci.USA, 120, 2023
7E7C	Crystal structure of ENL YEATS domain T1 mutant in complex with histone H3 acetylation at K27 分子名称: 1,2-ETHANEDIOL, Histone H3K27ac(24-27) peptide, IODIDE ION, ... 著者 Li, Y, Li, H. 登録日 2021-02-25 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Crystal structure of ENL YEATS domain T1 mutant in complex with histone H3 acetylation at K27 To Be Published
7X8F	Crystal structure of ENL T4 mutant YEATS domain in complex with histone H3 acetylation at K27 分子名称: CHLORIDE ION, H3K27ac(24-27) peptide, Protein ENL 著者 Li, Y, Peng, B, Li, H. 登録日 2022-03-12 公開日 2023-01-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. Mol.Cell, 82, 2022
7X88	Crystal structure of ENL YEATS domain T2 mutant in complex with histone H3 acetylation at K27 分子名称: CITRIC ACID, Histone H3K27ac(24-27) peptide, Protein ENL 著者 Li, Y.Y, Li, H.T. 登録日 2022-03-11 公開日 2023-01-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. Mol.Cell, 82, 2022
6KN5	Crystal structure of AFF4 C-terminal domain 分子名称: AF4/FMR2 family member 4 著者 Chen, L.J, Yang, W.S, Xu, R.M. 登録日 2019-08-03 公開日 2020-07-08 最終更新日 2022-03-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Acetylation of histone H3K27 signals the transcriptional elongation for estrogen receptor alpha. Commun Biol, 3, 2020
5YE4	Crystal structure of the complex of di-acetylated histone H4 and 1A9D7 Fab fragment 分子名称: 1A9D7 L chain, 1A9D7 VH CH1 chain, ZINC ION, ... 著者 Matsuda, T, Ito, T, Wakamori, M, Umehara, T. 登録日 2017-09-15 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states. Epigenetics, 13, 2018
5YE3	Crystal structure of the complex of di-acetylated histone H4 and 2A7D9 Fab fragment 分子名称: 2A7D9 L chain, 2A7D9 VH CH1 chain, di-acetylated histone H4 著者 Matsuda, T, Ito, T, Wakamori, M, Umehara, T. 登録日 2017-09-15 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states. Epigenetics, 13, 2018