7KHP
Acyl-enzyme intermediate structure of SARS-CoV-2 Mpro in complex with its C-terminal autoprocessing sequence.
Replaces: 7JOXSummary for 7KHP
Entry DOI | 10.2210/pdb7khp/pdb |
Related | 7JOY 7JP1 |
Descriptor | 3C-like proteinase, DIMETHYL SULFOXIDE (3 entities in total) |
Functional Keywords | protease, sars-cov-2, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
Total number of polymer chains | 2 |
Total formula weight | 67885.49 |
Authors | Lee, J.,Worrall, L.J.,Paetzel, M.,Strynadka, N.C.J. (deposition date: 2020-10-21, release date: 2020-10-28, Last modification date: 2023-10-18) |
Primary citation | Lee, J.,Worrall, L.J.,Vuckovic, M.,Rosell, F.I.,Gentile, F.,Ton, A.T.,Caveney, N.A.,Ban, F.,Cherkasov, A.,Paetzel, M.,Strynadka, N.C.J. Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site. Nat Commun, 11:5877-5877, 2020 Cited by PubMed: 33208735DOI: 10.1038/s41467-020-19662-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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