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4HYP

Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.

Resources
File formatFile name (file size)
PDBx/mmCIF4hyp.cif.gz Display(169.24 KB)
4hyp.cif
PDBx/mmJSONall4hyp.json.gz Display (Tree)(106.31 KB)
4hyp.json
no-atom4hyp-noatom.json.gz Display (Header)(15.65 KB)
4hyp-noatom.json
add only4hyp-plus.json.gz Display(1.30 KB)
4hyp-plus.json
PDBMLall4hyp.xml.gz Display(232.60 KB)
4hyp.xml
no-atom4hyp-noatom.xml.gz Display(39.84 KB)
4hyp-noatom.xml
ext-atom4hyp-extatom.xml.gz Display(144.69 KB)
4hyp-extatom.xml
PDBpdb4hyp.ent.gz Display(134.07 KB)
pdb4hyp.ent
RDF4hyp.rdf.gz Visualize(112.17 KB)
4hyp.rdf
Structure factorsr4hypsf.ent.gz Display(343.55 KB)
r4hypsf.ent
Biological unit (mmCIF format)4hyp-assembly1.cif.gz Display(43.92 KB)
4hyp-assembly1.cif (A)

*author defined assembly, 1 molecule(s) (monomeric)

4hyp-assembly2.cif.gz Display(44.35 KB)
4hyp-assembly2.cif (B)

*author defined assembly, 1 molecule(s) (monomeric)

4hyp-assembly3.cif.gz Display(44.23 KB)
4hyp-assembly3.cif (C)

*author defined assembly, 1 molecule(s) (monomeric)

4hyp-assembly4.cif.gz Display(43.86 KB)
4hyp-assembly4.cif (D)

*author defined assembly, 1 molecule(s) (monomeric)

4hyp-assembly5.cif.gz Display(82.05 KB)
4hyp-assembly5.cif (A,B)

*software defined assembly, 2 molecule(s) (dimeric)

4hyp-assembly6.cif.gz Display(81.93 KB)
4hyp-assembly6.cif (C,D)

*software defined assembly, 2 molecule(s) (dimeric)

Biological unit (PDB format)4hyp.pdb1.gz Display(33.78 KB)
4hyp.pdb1 (A)

*author defined assembly, 1 molecule(s) (monomeric)

4hyp.pdb2.gz Display(34.29 KB)
4hyp.pdb2 (B)

*author defined assembly, 1 molecule(s) (monomeric)

4hyp.pdb3.gz Display(34.50 KB)
4hyp.pdb3 (C)

*author defined assembly, 1 molecule(s) (monomeric)

4hyp.pdb4.gz Display(34.32 KB)
4hyp.pdb4 (D)

*author defined assembly, 1 molecule(s) (monomeric)

4hyp.pdb5.gz Display(64.85 KB)
4hyp.pdb5 (A,B)

*software defined assembly, 2 molecule(s) (dimeric)

4hyp.pdb6.gz Display(65.68 KB)
4hyp.pdb6 (C,D)

*software defined assembly, 2 molecule(s) (dimeric)

Validation reportsPDF4hyp_validation.pdf.gz Display(1.41 MB)
4hyp_validation.pdf
PDF-full4hyp_full_validation.pdf.gz Display(1.43 MB)
4hyp_full_validation.pdf
mmCIF4hyp_validation.cif.gz Display(50.87 KB)
4hyp_validation.cif
XML4hyp_validation.xml.gz Display(36.81 KB)
4hyp_validation.xml
PNG4hyp_multipercentile_validation.png.gz Display(169.37 KB)
4hyp_multipercentile_validation.png
SVG4hyp_multipercentile_validation.svg.gz Display(975.00 B)
4hyp_multipercentile_validation.svg
EDMap2fo-fc (PDBx/mmCIF)4hyp_validation_2fo-fc_map_coef.cif.gz Display(244.03 KB)
4hyp_validation_2fo-fc_map_coef.cif
fo-fc (PDBx/mmCIF)4hyp_validation_fo-fc_map_coef.cif.gz Display(234.95 KB)
4hyp_validation_fo-fc_map_coef.cif
2fo-fc (MTZ)4hyp_validation_2fo-fc_map_coef.mtz Visualize(565.73 KB)
fo-fc (MTZ)4hyp_validation_fo-fc_map_coef.mtz Visualize(565.73 KB)

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PDB entries from 2024-07-24

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