Summary
| Title: | Structure of Aldehyde Reductase Holoenzyme in Complex with the Potent Aldose Reductase Inhibitor Fidarestat: Implications for Inhibitor Binding and Selectivity |
| Citation: | El-Kabbani, O.,Carbone, V.,Darmanin, C.,Oka, M.,Mitschler, A.,Podjarny, A.,Schulze-Briese, C.,Chung, R.P. Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. J.Med.Chem., 48:5536-5542, 2005 PubMed: 16107153DOI: 10.1021/jm050412o |
| Experimental method: | X-RAY DIFFRACTION (1.85 Å) |
| Deposition date: | 2005-08-11 |
| Release date: | 2005-10-04 |
| Obsoletion date: | 2009-05-05 |
Timeline
Downloads
| File format | File name (file size) | ||
| PDBx/mmCIF | 2ao0.cif.gz Display(84.80 KB) 2ao0.cif | ||
| PDBML | all | 2ao0.xml.gz Display(114.26 KB) 2ao0.xml | |
| PDB | pdb2ao0.ent.gz Display(69.03 KB) pdb2ao0.ent | ||
| Structure factors | r2ao0sf.ent.gz Display(257.86 KB) r2ao0sf.ent | ||
