7G5H
Crystal Structure of rat Autotaxin in complex with 1-[(3aR,6aR)-5-(1H-benzotriazole-5-carbonyl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-2-yl]-3-[4-(trifluoromethoxy)phenyl]propan-1-one, i.e. SMILES N1(C[C@H]2[C@H](C1)CN(C2)C(=O)c1ccc2c(c1)N=NN2)C(=O)CCc1ccc(cc1)OC(F)(F)F with IC50=0.0098589 microM
History
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Version | Date | Type | |
1-0 | 2024-12-18 | Initial release |