9ZUZ

Translation Initiation Factor eIF-2B complex with the Isohexide Diamine GSK735

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002183	biological_process	cytoplasmic translational initiation
A	0003743	molecular_function	translation initiation factor activity
A	0005085	molecular_function	guanyl-nucleotide exchange factor activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005851	cellular_component	eukaryotic translation initiation factor 2B complex
A	0005886	cellular_component	plasma membrane
A	0006413	biological_process	translational initiation
A	0009408	biological_process	response to heat
A	0009749	biological_process	response to glucose
A	0014003	biological_process	oligodendrocyte development
A	0016020	cellular_component	membrane
A	0042802	molecular_function	identical protein binding
A	0043434	biological_process	response to peptide hormone
A	0045948	biological_process	positive regulation of translational initiation
A	0050852	biological_process	T cell receptor signaling pathway
B	0001541	biological_process	ovarian follicle development
B	0002183	biological_process	cytoplasmic translational initiation
B	0003743	molecular_function	translation initiation factor activity
B	0005085	molecular_function	guanyl-nucleotide exchange factor activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005851	cellular_component	eukaryotic translation initiation factor 2B complex
B	0006413	biological_process	translational initiation
B	0006446	biological_process	regulation of translational initiation
B	0007417	biological_process	central nervous system development
B	0009408	biological_process	response to heat
B	0009749	biological_process	response to glucose
B	0014003	biological_process	oligodendrocyte development
B	0042552	biological_process	myelination
B	0043434	biological_process	response to peptide hormone
B	0045948	biological_process	positive regulation of translational initiation
B	0048513	biological_process	animal organ development
B	0050852	biological_process	T cell receptor signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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