9ZOH
Cryo-EM structure of the complete Sulfolobus acidocaldarius RNA polymerase in open clamp conformation
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SyslktieehFvpYSIAKKYIkELIdTGS |
| Chain | Residue | Details |
| F | SER2-SER30 |
| site_id | PS00446 |
| Number of Residues | 41 |
| Details | RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSIRRasilyvpvmAvdeVyfieNnSplyDEiLAhRLALVP |
| Chain | Residue | Details |
| D | ASN26-PRO66 |
| site_id | PS01110 |
| Number of Residues | 14 |
| Details | RNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPKHeiLqlEE |
| Chain | Residue | Details |
| H | HIS14-GLU27 |
| site_id | PS01111 |
| Number of Residues | 15 |
| Details | RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYEiARiISaRAlQ |
| Chain | Residue | Details |
| K | THR19-GLN33 |
| site_id | PS01112 |
| Number of Residues | 10 |
| Details | RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IIPIrCFTCG |
| Chain | Residue | Details |
| N | ILE2-GLY11 |
| site_id | PS01154 |
| Number of Residues | 32 |
| Details | RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. IdgEeHTIgNlLkgmLlkvpgVkfaaYslpHP |
| Chain | Residue | Details |
| L | ILE17-PRO48 |
| site_id | PS01166 |
| Number of Residues | 13 |
| Details | RNA_POL_BETA RNA polymerases beta chain signature. GdKFATrHGQKGV |
| Chain | Residue | Details |
| B | GLY873-VAL885 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00863","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"34535646","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OK0","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OQ4","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OQY","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00863","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"34535646","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OK0","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OQ4","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"34535646","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OK0","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OQ4","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OQY","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"34535646","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OK0","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OQY","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"34535646","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OK0","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 82 |
| Details | Domain: {"description":"S1 motif","evidences":[{"source":"HAMAP-Rule","id":"MF_00865","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00250","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"34535646","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OK0","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OQ4","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OQY","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 10 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"34535646","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00320","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"34535646","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OK0","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"34535646","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OQ4","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OQY","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00615","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"34535646","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7OK0","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OQ4","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OQY","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
