9YB5

Cryo-EM structure of human importin Beta:Ran-GDP:RanBP1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
D	0000054	biological_process	ribosomal subunit export from nucleus
D	0000055	biological_process	ribosomal large subunit export from nucleus
D	0000056	biological_process	ribosomal small subunit export from nucleus
D	0000070	biological_process	mitotic sister chromatid segregation
D	0000278	biological_process	mitotic cell cycle
D	0000287	molecular_function	magnesium ion binding
D	0000785	cellular_component	chromatin
D	0003682	molecular_function	chromatin binding
D	0003723	molecular_function	RNA binding
D	0003924	molecular_function	GTPase activity
D	0003925	molecular_function	G protein activity
D	0005049	molecular_function	nuclear export signal receptor activity
D	0005515	molecular_function	protein binding
D	0005525	molecular_function	GTP binding
D	0005634	cellular_component	nucleus
D	0005635	cellular_component	nuclear envelope
D	0005643	cellular_component	nuclear pore
D	0005654	cellular_component	nucleoplasm
D	0005730	cellular_component	nucleolus
D	0005737	cellular_component	cytoplasm
D	0005814	cellular_component	centriole
D	0005829	cellular_component	cytosol
D	0006259	biological_process	DNA metabolic process
D	0006606	biological_process	protein import into nucleus
D	0006611	biological_process	protein export from nucleus
D	0006913	biological_process	nucleocytoplasmic transport
D	0007052	biological_process	mitotic spindle organization
D	0016020	cellular_component	membrane
D	0016032	biological_process	viral process
D	0019003	molecular_function	GDP binding
D	0030496	cellular_component	midbody
D	0032991	cellular_component	protein-containing complex
D	0035281	biological_process	pre-miRNA export from nucleus
D	0042307	biological_process	positive regulation of protein import into nucleus
D	0042470	cellular_component	melanosome
D	0042565	cellular_component	RNA nuclear export complex
D	0045296	molecular_function	cadherin binding
D	0046039	biological_process	GTP metabolic process
D	0046982	molecular_function	protein heterodimerization activity
D	0055037	cellular_component	recycling endosome
D	0061015	biological_process	snRNA import into nucleus
D	0070062	cellular_component	extracellular exosome
D	0070883	molecular_function	pre-miRNA binding
D	0090543	cellular_component	Flemming body
D	1902570	biological_process	protein localization to nucleolus

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	29
Details	Repeat: {"description":"HEAT 1","evidences":[{"source":"PubMed","id":"10353244","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	80
Details	Domain: {"description":"Importin N-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00115","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	32
Details	Repeat: {"description":"HEAT 2","evidences":[{"source":"PubMed","id":"10353244","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	38
Details	Repeat: {"description":"HEAT 3","evidences":[{"source":"PubMed","id":"10353244","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	31
Details	Repeat: {"description":"HEAT 4","evidences":[{"source":"PubMed","id":"10353244","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	32
Details	Repeat: {"description":"HEAT 5","evidences":[{"source":"PubMed","id":"10353244","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	35
Details	Repeat: {"description":"HEAT 6","evidences":[{"source":"PubMed","id":"10353244","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	49
Details	Repeat: {"description":"HEAT 7","evidences":[{"source":"PubMed","id":"10353244","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	46
Details	Repeat: {"description":"HEAT 8","evidences":[{"source":"PubMed","id":"10353244","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	30
Details	Repeat: {"description":"HEAT 9","evidences":[{"source":"PubMed","id":"10353244","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	36
Details	Repeat: {"description":"HEAT 10","evidences":[{"source":"PubMed","id":"10353244","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	13
Details	Region: {"description":"IAB-binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	85
Details	Region: {"description":"Ran-GTP binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	3
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	8
Details	Region: {"description":"Switch-I","evidences":[{"source":"PROSITE-ProRule","id":"PRU00752","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	16
Details	Region: {"description":"Switch-II","evidences":[{"source":"PROSITE-ProRule","id":"PRU00752","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611384","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19505478","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IBR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K5G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IBR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611384","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19505478","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IBR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611384","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19505478","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IBR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CJ2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611384","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19505478","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1K5G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CJ2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	1
Details	Site: {"description":"Essential for GTP hydrolysis","evidences":[{"source":"PubMed","id":"18591255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8636225","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"31075303","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"29040603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62827","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate"}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P34022","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---