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9WI0

cryo-EM structure of E.coli ArnA

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0005515molecular_functionprotein binding
A0006629biological_processlipid metabolic process
A0009103biological_processlipopolysaccharide biosynthetic process
A0009245biological_processlipid A biosynthetic process
A0016020cellular_componentmembrane
A0016491molecular_functionoxidoreductase activity
A0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A0016740molecular_functiontransferase activity
A0016742molecular_functionhydroxymethyl-, formyl- and related transferase activity
A0032991cellular_componentprotein-containing complex
A0033320biological_processUDP-D-xylose biosynthetic process
A0042802molecular_functionidentical protein binding
A0046493biological_processlipid A metabolic process
A0046677biological_processresponse to antibiotic
A0048040molecular_functionUDP-glucuronate decarboxylase activity
A0070403molecular_functionNAD+ binding
A0099618molecular_functionUDP-glucuronate dehydrogenase activity
A0099619molecular_functionUDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
A2001315biological_processUDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
B0003824molecular_functioncatalytic activity
B0005515molecular_functionprotein binding
B0006629biological_processlipid metabolic process
B0009103biological_processlipopolysaccharide biosynthetic process
B0009245biological_processlipid A biosynthetic process
B0016020cellular_componentmembrane
B0016491molecular_functionoxidoreductase activity
B0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B0016740molecular_functiontransferase activity
B0016742molecular_functionhydroxymethyl-, formyl- and related transferase activity
B0032991cellular_componentprotein-containing complex
B0033320biological_processUDP-D-xylose biosynthetic process
B0042802molecular_functionidentical protein binding
B0046493biological_processlipid A metabolic process
B0046677biological_processresponse to antibiotic
B0048040molecular_functionUDP-glucuronate decarboxylase activity
B0070403molecular_functionNAD+ binding
B0099618molecular_functionUDP-glucuronate dehydrogenase activity
B0099619molecular_functionUDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
B2001315biological_processUDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
C0003824molecular_functioncatalytic activity
C0005515molecular_functionprotein binding
C0006629biological_processlipid metabolic process
C0009103biological_processlipopolysaccharide biosynthetic process
C0009245biological_processlipid A biosynthetic process
C0016020cellular_componentmembrane
C0016491molecular_functionoxidoreductase activity
C0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C0016740molecular_functiontransferase activity
C0016742molecular_functionhydroxymethyl-, formyl- and related transferase activity
C0032991cellular_componentprotein-containing complex
C0033320biological_processUDP-D-xylose biosynthetic process
C0042802molecular_functionidentical protein binding
C0046493biological_processlipid A metabolic process
C0046677biological_processresponse to antibiotic
C0048040molecular_functionUDP-glucuronate decarboxylase activity
C0070403molecular_functionNAD+ binding
C0099618molecular_functionUDP-glucuronate dehydrogenase activity
C0099619molecular_functionUDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
C2001315biological_processUDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
D0003824molecular_functioncatalytic activity
D0005515molecular_functionprotein binding
D0006629biological_processlipid metabolic process
D0009103biological_processlipopolysaccharide biosynthetic process
D0009245biological_processlipid A biosynthetic process
D0016020cellular_componentmembrane
D0016491molecular_functionoxidoreductase activity
D0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D0016740molecular_functiontransferase activity
D0016742molecular_functionhydroxymethyl-, formyl- and related transferase activity
D0032991cellular_componentprotein-containing complex
D0033320biological_processUDP-D-xylose biosynthetic process
D0042802molecular_functionidentical protein binding
D0046493biological_processlipid A metabolic process
D0046677biological_processresponse to antibiotic
D0048040molecular_functionUDP-glucuronate decarboxylase activity
D0070403molecular_functionNAD+ binding
D0099618molecular_functionUDP-glucuronate dehydrogenase activity
D0099619molecular_functionUDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
D2001315biological_processUDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
E0003824molecular_functioncatalytic activity
E0005515molecular_functionprotein binding
E0006629biological_processlipid metabolic process
E0009103biological_processlipopolysaccharide biosynthetic process
E0009245biological_processlipid A biosynthetic process
E0016020cellular_componentmembrane
E0016491molecular_functionoxidoreductase activity
E0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
E0016740molecular_functiontransferase activity
E0016742molecular_functionhydroxymethyl-, formyl- and related transferase activity
E0032991cellular_componentprotein-containing complex
E0033320biological_processUDP-D-xylose biosynthetic process
E0042802molecular_functionidentical protein binding
E0046493biological_processlipid A metabolic process
E0046677biological_processresponse to antibiotic
E0048040molecular_functionUDP-glucuronate decarboxylase activity
E0070403molecular_functionNAD+ binding
E0099618molecular_functionUDP-glucuronate dehydrogenase activity
E0099619molecular_functionUDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
E2001315biological_processUDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
F0003824molecular_functioncatalytic activity
F0005515molecular_functionprotein binding
F0006629biological_processlipid metabolic process
F0009103biological_processlipopolysaccharide biosynthetic process
F0009245biological_processlipid A biosynthetic process
F0016020cellular_componentmembrane
F0016491molecular_functionoxidoreductase activity
F0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
F0016740molecular_functiontransferase activity
F0016742molecular_functionhydroxymethyl-, formyl- and related transferase activity
F0032991cellular_componentprotein-containing complex
F0033320biological_processUDP-D-xylose biosynthetic process
F0042802molecular_functionidentical protein binding
F0046493biological_processlipid A metabolic process
F0046677biological_processresponse to antibiotic
F0048040molecular_functionUDP-glucuronate decarboxylase activity
F0070403molecular_functionNAD+ binding
F0099618molecular_functionUDP-glucuronate dehydrogenase activity
F0099619molecular_functionUDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
F2001315biological_processUDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1818
DetailsRegion: {"description":"Formyltransferase ArnAFT"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues6
DetailsActive site: {"description":"Proton donor; for formyltransferase activity"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues6
DetailsActive site: {"description":"Proton acceptor; for decarboxylase activity"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues6
DetailsActive site: {"description":"Proton donor; for decarboxylase activity"}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues144
DetailsBinding site: {}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues6
DetailsSite: {"description":"Transition state stabilizer"}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues6
DetailsSite: {"description":"Raises pKa of active site His"}
ChainResidueDetails

246704

PDB entries from 2025-12-24

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