9VUL

Cryo-EM structure of the human measles virus RNA-dependent RNA polymerase bound to allosteric inhibitor ERDRP-0519

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0006974	biological_process	DNA damage response
A	0008643	biological_process	carbohydrate transport
A	0015768	biological_process	maltose transport
A	0016020	cellular_component	membrane
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0034219	biological_process	carbohydrate transmembrane transport
A	0034289	biological_process	detection of maltose stimulus
A	0042597	cellular_component	periplasmic space
A	0042956	biological_process	maltodextrin transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0060326	biological_process	cell chemotaxis
A	1901982	molecular_function	maltose binding
A	1990060	cellular_component	maltose transport complex
B	0005515	molecular_function	protein binding
B	0006974	biological_process	DNA damage response
B	0008643	biological_process	carbohydrate transport
B	0015768	biological_process	maltose transport
B	0016020	cellular_component	membrane
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0034219	biological_process	carbohydrate transmembrane transport
B	0034289	biological_process	detection of maltose stimulus
B	0042597	cellular_component	periplasmic space
B	0042956	biological_process	maltodextrin transmembrane transport
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0060326	biological_process	cell chemotaxis
B	1901982	molecular_function	maltose binding
B	1990060	cellular_component	maltose transport complex
C	0005515	molecular_function	protein binding
C	0006974	biological_process	DNA damage response
C	0008643	biological_process	carbohydrate transport
C	0015768	biological_process	maltose transport
C	0016020	cellular_component	membrane
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0034219	biological_process	carbohydrate transmembrane transport
C	0034289	biological_process	detection of maltose stimulus
C	0042597	cellular_component	periplasmic space
C	0042956	biological_process	maltodextrin transmembrane transport
C	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	0060326	biological_process	cell chemotaxis
C	1901982	molecular_function	maltose binding
C	1990060	cellular_component	maltose transport complex
D	0005515	molecular_function	protein binding
D	0006974	biological_process	DNA damage response
D	0008643	biological_process	carbohydrate transport
D	0015768	biological_process	maltose transport
D	0016020	cellular_component	membrane
D	0030288	cellular_component	outer membrane-bounded periplasmic space
D	0034219	biological_process	carbohydrate transmembrane transport
D	0034289	biological_process	detection of maltose stimulus
D	0042597	cellular_component	periplasmic space
D	0042956	biological_process	maltodextrin transmembrane transport
D	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
D	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
D	0060326	biological_process	cell chemotaxis
D	1901982	molecular_function	maltose binding
D	1990060	cellular_component	maltose transport complex
L	0000166	molecular_function	nucleotide binding
L	0001172	biological_process	RNA-templated transcription
L	0003824	molecular_function	catalytic activity
L	0003924	molecular_function	GTPase activity
L	0003968	molecular_function	RNA-directed RNA polymerase activity
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0006370	biological_process	7-methylguanosine mRNA capping
L	0006397	biological_process	mRNA processing
L	0006974	biological_process	DNA damage response
L	0008168	molecular_function	methyltransferase activity
L	0008643	biological_process	carbohydrate transport
L	0015768	biological_process	maltose transport
L	0016020	cellular_component	membrane
L	0016740	molecular_function	transferase activity
L	0016779	molecular_function	nucleotidyltransferase activity
L	0016787	molecular_function	hydrolase activity
L	0030288	cellular_component	outer membrane-bounded periplasmic space
L	0030430	cellular_component	host cell cytoplasm
L	0034062	molecular_function	5'-3' RNA polymerase activity
L	0034219	biological_process	carbohydrate transmembrane transport
L	0034289	biological_process	detection of maltose stimulus
L	0042597	cellular_component	periplasmic space
L	0042956	biological_process	maltodextrin transmembrane transport
L	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
L	0046872	molecular_function	metal ion binding
L	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
L	0060326	biological_process	cell chemotaxis
L	0062105	molecular_function	RNA 2'-O-methyltransferase activity
L	0106005	biological_process	RNA 5'-cap (guanine-N7)-methylation
L	1901982	molecular_function	maltose binding
L	1990060	cellular_component	maltose transport complex

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO24-ASN41

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	46
Details	Region: {"description":"Interaction with the L polymerase","evidences":[{"source":"UniProtKB","id":"Q9WMB4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	184
Details	Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q997F0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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