9TAY

Structure of the human inner kinetochore CCAN bound to a di-CENP-A nucleosome

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000132	biological_process	establishment of mitotic spindle orientation
A	0000281	biological_process	mitotic cytokinesis
A	0000775	cellular_component	chromosome, centromeric region
A	0000776	cellular_component	kinetochore
A	0000779	cellular_component	condensed chromosome, centromeric region
A	0000786	cellular_component	nucleosome
A	0003682	molecular_function	chromatin binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005721	cellular_component	pericentric heterochromatin
A	0005829	cellular_component	cytosol
A	0007080	biological_process	mitotic metaphase chromosome alignment
A	0030527	molecular_function	structural constituent of chromatin
A	0034080	biological_process	CENP-A containing chromatin assembly
A	0043505	cellular_component	CENP-A containing nucleosome
A	0051382	biological_process	kinetochore assembly
A	0061638	cellular_component	CENP-A containing chromatin
A	0061644	biological_process	protein localization to CENP-A containing chromatin
A	0071459	biological_process	protein localization to chromosome, centromeric region
B	0000781	cellular_component	chromosome, telomeric region
B	0000786	cellular_component	nucleosome
B	0003677	molecular_function	DNA binding
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005694	cellular_component	chromosome
B	0006325	biological_process	chromatin organization
B	0006334	biological_process	nucleosome assembly
B	0016020	cellular_component	membrane
B	0030527	molecular_function	structural constituent of chromatin
B	0032200	biological_process	telomere organization
B	0032991	cellular_component	protein-containing complex
B	0043505	cellular_component	CENP-A containing nucleosome
B	0045653	biological_process	negative regulation of megakaryocyte differentiation
B	0061644	biological_process	protein localization to CENP-A containing chromatin
B	0070062	cellular_component	extracellular exosome
c	0000132	biological_process	establishment of mitotic spindle orientation
c	0000281	biological_process	mitotic cytokinesis
c	0000775	cellular_component	chromosome, centromeric region
c	0000776	cellular_component	kinetochore
c	0000779	cellular_component	condensed chromosome, centromeric region
c	0000786	cellular_component	nucleosome
c	0003682	molecular_function	chromatin binding
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005721	cellular_component	pericentric heterochromatin
c	0005829	cellular_component	cytosol
c	0007080	biological_process	mitotic metaphase chromosome alignment
c	0030527	molecular_function	structural constituent of chromatin
c	0034080	biological_process	CENP-A containing chromatin assembly
c	0043505	cellular_component	CENP-A containing nucleosome
c	0051382	biological_process	kinetochore assembly
c	0061638	cellular_component	CENP-A containing chromatin
c	0061644	biological_process	protein localization to CENP-A containing chromatin
c	0071459	biological_process	protein localization to chromosome, centromeric region
C	0000786	cellular_component	nucleosome
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005694	cellular_component	chromosome
C	0006325	biological_process	chromatin organization
C	0008285	biological_process	negative regulation of cell population proliferation
C	0030527	molecular_function	structural constituent of chromatin
C	0031507	biological_process	heterochromatin formation
C	0070062	cellular_component	extracellular exosome
d	0000781	cellular_component	chromosome, telomeric region
d	0000786	cellular_component	nucleosome
d	0003677	molecular_function	DNA binding
d	0003723	molecular_function	RNA binding
d	0005515	molecular_function	protein binding
d	0005576	cellular_component	extracellular region
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005694	cellular_component	chromosome
d	0006325	biological_process	chromatin organization
d	0006334	biological_process	nucleosome assembly
d	0016020	cellular_component	membrane
d	0030527	molecular_function	structural constituent of chromatin
d	0032200	biological_process	telomere organization
d	0032991	cellular_component	protein-containing complex
d	0043505	cellular_component	CENP-A containing nucleosome
d	0045653	biological_process	negative regulation of megakaryocyte differentiation
d	0061644	biological_process	protein localization to CENP-A containing chromatin
d	0070062	cellular_component	extracellular exosome
D	0000786	cellular_component	nucleosome
D	0002227	biological_process	innate immune response in mucosa
D	0003677	molecular_function	DNA binding
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005694	cellular_component	chromosome
D	0006325	biological_process	chromatin organization
D	0006334	biological_process	nucleosome assembly
D	0019731	biological_process	antibacterial humoral response
D	0030527	molecular_function	structural constituent of chromatin
D	0042802	molecular_function	identical protein binding
D	0050830	biological_process	defense response to Gram-positive bacterium
D	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
D	0070062	cellular_component	extracellular exosome
e	0000786	cellular_component	nucleosome
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005694	cellular_component	chromosome
e	0006325	biological_process	chromatin organization
e	0008285	biological_process	negative regulation of cell population proliferation
e	0030527	molecular_function	structural constituent of chromatin
e	0031507	biological_process	heterochromatin formation
e	0070062	cellular_component	extracellular exosome
E	0000132	biological_process	establishment of mitotic spindle orientation
E	0000281	biological_process	mitotic cytokinesis
E	0000775	cellular_component	chromosome, centromeric region
E	0000776	cellular_component	kinetochore
E	0000779	cellular_component	condensed chromosome, centromeric region
E	0000786	cellular_component	nucleosome
E	0003682	molecular_function	chromatin binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005721	cellular_component	pericentric heterochromatin
E	0005829	cellular_component	cytosol
E	0007080	biological_process	mitotic metaphase chromosome alignment
E	0030527	molecular_function	structural constituent of chromatin
E	0034080	biological_process	CENP-A containing chromatin assembly
E	0043505	cellular_component	CENP-A containing nucleosome
E	0051382	biological_process	kinetochore assembly
E	0061638	cellular_component	CENP-A containing chromatin
E	0061644	biological_process	protein localization to CENP-A containing chromatin
E	0071459	biological_process	protein localization to chromosome, centromeric region
f	0000786	cellular_component	nucleosome
f	0002227	biological_process	innate immune response in mucosa
f	0003677	molecular_function	DNA binding
f	0005515	molecular_function	protein binding
f	0005576	cellular_component	extracellular region
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005694	cellular_component	chromosome
f	0006325	biological_process	chromatin organization
f	0006334	biological_process	nucleosome assembly
f	0019731	biological_process	antibacterial humoral response
f	0030527	molecular_function	structural constituent of chromatin
f	0042802	molecular_function	identical protein binding
f	0050830	biological_process	defense response to Gram-positive bacterium
f	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
f	0070062	cellular_component	extracellular exosome
F	0000781	cellular_component	chromosome, telomeric region
F	0000786	cellular_component	nucleosome
F	0003677	molecular_function	DNA binding
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005694	cellular_component	chromosome
F	0006325	biological_process	chromatin organization
F	0006334	biological_process	nucleosome assembly
F	0016020	cellular_component	membrane
F	0030527	molecular_function	structural constituent of chromatin
F	0032200	biological_process	telomere organization
F	0032991	cellular_component	protein-containing complex
F	0043505	cellular_component	CENP-A containing nucleosome
F	0045653	biological_process	negative regulation of megakaryocyte differentiation
F	0061644	biological_process	protein localization to CENP-A containing chromatin
F	0070062	cellular_component	extracellular exosome
g	0000132	biological_process	establishment of mitotic spindle orientation
g	0000281	biological_process	mitotic cytokinesis
g	0000775	cellular_component	chromosome, centromeric region
g	0000776	cellular_component	kinetochore
g	0000779	cellular_component	condensed chromosome, centromeric region
g	0000786	cellular_component	nucleosome
g	0003682	molecular_function	chromatin binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005721	cellular_component	pericentric heterochromatin
g	0005829	cellular_component	cytosol
g	0007080	biological_process	mitotic metaphase chromosome alignment
g	0030527	molecular_function	structural constituent of chromatin
g	0034080	biological_process	CENP-A containing chromatin assembly
g	0043505	cellular_component	CENP-A containing nucleosome
g	0051382	biological_process	kinetochore assembly
g	0061638	cellular_component	CENP-A containing chromatin
g	0061644	biological_process	protein localization to CENP-A containing chromatin
g	0071459	biological_process	protein localization to chromosome, centromeric region
G	0000786	cellular_component	nucleosome
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005694	cellular_component	chromosome
G	0006325	biological_process	chromatin organization
G	0008285	biological_process	negative regulation of cell population proliferation
G	0030527	molecular_function	structural constituent of chromatin
G	0031507	biological_process	heterochromatin formation
G	0070062	cellular_component	extracellular exosome
h	0000781	cellular_component	chromosome, telomeric region
h	0000786	cellular_component	nucleosome
h	0003677	molecular_function	DNA binding
h	0003723	molecular_function	RNA binding
h	0005515	molecular_function	protein binding
h	0005576	cellular_component	extracellular region
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0005694	cellular_component	chromosome
h	0006325	biological_process	chromatin organization
h	0006334	biological_process	nucleosome assembly
h	0016020	cellular_component	membrane
h	0030527	molecular_function	structural constituent of chromatin
h	0032200	biological_process	telomere organization
h	0032991	cellular_component	protein-containing complex
h	0043505	cellular_component	CENP-A containing nucleosome
h	0045653	biological_process	negative regulation of megakaryocyte differentiation
h	0061644	biological_process	protein localization to CENP-A containing chromatin
h	0070062	cellular_component	extracellular exosome
H	0000776	cellular_component	kinetochore
H	0000939	cellular_component	inner kinetochore
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005694	cellular_component	chromosome
H	0005829	cellular_component	cytosol
H	0007052	biological_process	mitotic spindle organization
H	0007059	biological_process	chromosome segregation
H	0043515	molecular_function	kinetochore binding
H	0051383	biological_process	kinetochore organization
i	0000786	cellular_component	nucleosome
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005694	cellular_component	chromosome
i	0006325	biological_process	chromatin organization
i	0008285	biological_process	negative regulation of cell population proliferation
i	0030527	molecular_function	structural constituent of chromatin
i	0031507	biological_process	heterochromatin formation
i	0070062	cellular_component	extracellular exosome
I	0000070	biological_process	mitotic sister chromatid segregation
I	0000775	cellular_component	chromosome, centromeric region
I	0000776	cellular_component	kinetochore
I	0000939	cellular_component	inner kinetochore
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005829	cellular_component	cytosol
I	0007059	biological_process	chromosome segregation
I	0007548	biological_process	sex differentiation
I	0016604	cellular_component	nuclear body
I	0034080	biological_process	CENP-A containing chromatin assembly
j	0000786	cellular_component	nucleosome
j	0002227	biological_process	innate immune response in mucosa
j	0003677	molecular_function	DNA binding
j	0005515	molecular_function	protein binding
j	0005576	cellular_component	extracellular region
j	0005634	cellular_component	nucleus
j	0005654	cellular_component	nucleoplasm
j	0005694	cellular_component	chromosome
j	0006325	biological_process	chromatin organization
j	0006334	biological_process	nucleosome assembly
j	0019731	biological_process	antibacterial humoral response
j	0030527	molecular_function	structural constituent of chromatin
j	0042802	molecular_function	identical protein binding
j	0050830	biological_process	defense response to Gram-positive bacterium
j	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
j	0070062	cellular_component	extracellular exosome
J	0000786	cellular_component	nucleosome
J	0002227	biological_process	innate immune response in mucosa
J	0003677	molecular_function	DNA binding
J	0005515	molecular_function	protein binding
J	0005576	cellular_component	extracellular region
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005694	cellular_component	chromosome
J	0006325	biological_process	chromatin organization
J	0006334	biological_process	nucleosome assembly
J	0019731	biological_process	antibacterial humoral response
J	0030527	molecular_function	structural constituent of chromatin
J	0042802	molecular_function	identical protein binding
J	0050830	biological_process	defense response to Gram-positive bacterium
J	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
J	0070062	cellular_component	extracellular exosome
K	0000775	cellular_component	chromosome, centromeric region
K	0000939	cellular_component	inner kinetochore
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005829	cellular_component	cytosol
K	0007059	biological_process	chromosome segregation
L	0000775	cellular_component	chromosome, centromeric region
L	0000939	cellular_component	inner kinetochore
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005829	cellular_component	cytosol
L	0007059	biological_process	chromosome segregation
M	0000939	cellular_component	inner kinetochore
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0007059	biological_process	chromosome segregation
N	0000939	cellular_component	inner kinetochore
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005829	cellular_component	cytosol
N	0007059	biological_process	chromosome segregation
P	0000775	cellular_component	chromosome, centromeric region
P	0000939	cellular_component	inner kinetochore
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005829	cellular_component	cytosol
P	0007059	biological_process	chromosome segregation
R	0000775	cellular_component	chromosome, centromeric region
R	0000939	cellular_component	inner kinetochore
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0007059	biological_process	chromosome segregation
R	0007155	biological_process	cell adhesion
R	0007165	biological_process	signal transduction
R	0016020	cellular_component	membrane
S	0000712	biological_process	resolution of meiotic recombination intermediates
S	0000775	cellular_component	chromosome, centromeric region
S	0000785	cellular_component	chromatin
S	0000939	cellular_component	inner kinetochore
S	0003677	molecular_function	DNA binding
S	0003682	molecular_function	chromatin binding
S	0003690	molecular_function	double-stranded DNA binding
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005829	cellular_component	cytosol
S	0006281	biological_process	DNA repair
S	0006974	biological_process	DNA damage response
S	0007059	biological_process	chromosome segregation
S	0031297	biological_process	replication fork processing
S	0031398	biological_process	positive regulation of protein ubiquitination
S	0036297	biological_process	interstrand cross-link repair
S	0043240	cellular_component	Fanconi anaemia nuclear complex
S	0071821	cellular_component	FANCM-MHF complex
T	0000278	biological_process	mitotic cell cycle
T	0000775	cellular_component	chromosome, centromeric region
T	0000776	cellular_component	kinetochore
T	0000939	cellular_component	inner kinetochore
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005829	cellular_component	cytosol
T	0007059	biological_process	chromosome segregation
T	0016604	cellular_component	nuclear body
T	0051276	biological_process	chromosome organization
T	0051382	biological_process	kinetochore assembly
W	0000278	biological_process	mitotic cell cycle
W	0000775	cellular_component	chromosome, centromeric region
W	0000776	cellular_component	kinetochore
W	0000939	cellular_component	inner kinetochore
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005730	cellular_component	nucleolus
W	0007059	biological_process	chromosome segregation
W	0016363	cellular_component	nuclear matrix
W	0034080	biological_process	CENP-A containing chromatin assembly
W	0051276	biological_process	chromosome organization
W	0051382	biological_process	kinetochore assembly
X	0000712	biological_process	resolution of meiotic recombination intermediates
X	0000775	cellular_component	chromosome, centromeric region
X	0000785	cellular_component	chromatin
X	0000939	cellular_component	inner kinetochore
X	0003677	molecular_function	DNA binding
X	0003690	molecular_function	double-stranded DNA binding
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005829	cellular_component	cytosol
X	0007059	biological_process	chromosome segregation
X	0031297	biological_process	replication fork processing
X	0031398	biological_process	positive regulation of protein ubiquitination
X	0036297	biological_process	interstrand cross-link repair
X	0043240	cellular_component	Fanconi anaemia nuclear complex
X	0071821	cellular_component	FANCM-MHF complex

Functional Information from PROSITE/UniProt

site_id	PS00046
Number of Residues	7
Details	HISTONE_H2A Histone H2A signature. AGLqFPV

Chain	Residue	Details
e	ALA21-VAL27

---

site_id	PS00047
Number of Residues	5
Details	HISTONE_H4 Histone H4 signature. GAKRH

Chain	Residue	Details
d	GLY14-HIS18

---

site_id	PS00357
Number of Residues	23
Details	HISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG

Chain	Residue	Details
f	ARG92-GLY114

---

site_id	PS00374
Number of Residues	7
Details	MGMT Methylated-DNA--protein-cysteine methyltransferase active site. IPCHRVV

Chain	Residue	Details
T	ILE-49-VAL-43

---

site_id	PS00959
Number of Residues	9
Details	HISTONE_H3_2 Histone H3 signature 2. PFsRLAREI

Chain	Residue	Details
c	PRO66-ILE74

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	99
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Site: {"description":"Breakpoint for translocation to form KMT2A/MLL1-CENPK oncogene"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	17
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	Motif: {"description":"LXXIL motif"}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	123
Details	Region: {"description":"CATD","evidences":[{"source":"PubMed","id":"15282608","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7962047","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"25556658","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	30
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"22389435","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	4
Details	Modified residue: {"description":"N6-propionyllysine; alternate","evidences":[{"source":"PubMed","id":"17267393","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine; by PAK2","evidences":[{"source":"PubMed","id":"21724829","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	8
Details	Modified residue: {"description":"N6-methacryllysine; alternate","evidences":[{"source":"PubMed","id":"34961760","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	4
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62806","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P62806","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate","evidences":[{"source":"PubMed","id":"30886146","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"19818714","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	4
Details	Modified residue: {"description":"N6-benzoyllysine; alternate","evidences":[{"source":"PubMed","id":"30154464","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	4
Details	Modified residue: {"description":"N6-isonicotinyllysine","evidences":[{"source":"PubMed","id":"34545082","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	4
Details	Modified residue: {"description":"N6-crotonyllysine; alternate","evidences":[{"source":"PubMed","id":"21925322","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	8
Details	Modified residue: {"description":"N6-(2-hydroxyisobutyryl)lysine","evidences":[{"source":"PubMed","id":"24681537","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	4
Details	Modified residue: {"description":"N5-methylglutamine","evidences":[{"source":"PubMed","id":"24352239","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"22713238","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22980979","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22713238","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22980979","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	4
Details	Modified residue: {"description":"PolyADP-ribosyl glutamic acid","evidences":[{"source":"UniProtKB","id":"Q64475","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine; by AMPK","evidences":[{"source":"UniProtKB","id":"Q6ZWY9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	4
Details	Modified residue: {"description":"N6-lactoyllysine; alternate","evidences":[{"source":"PubMed","id":"31645732","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	8
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"16627869","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	4
Details	Modified residue: {"description":"N6-isonicotinyllysine; alternate","evidences":[{"source":"PubMed","id":"34545082","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	4
Details	Modified residue: {"description":"Dimethylated arginine","evidences":[{"source":"UniProtKB","id":"Q96A08","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	8
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"UniProtKB","id":"Q96A08","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q00729","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	4
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"source":"PubMed","id":"22121020","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"21726816","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"16307923","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16627869","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16713563","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22121020","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---