Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9TAN

Local refinement of E. coli Complex I D79N NuoA mutant hydrophilic domain in LMNG

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0003954	molecular_function	NADH dehydrogenase activity
B	0005506	molecular_function	iron ion binding
B	0005886	cellular_component	plasma membrane
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0009060	biological_process	aerobic respiration
B	0015990	biological_process	electron transport coupled proton transport
B	0016020	cellular_component	membrane
B	0022904	biological_process	respiratory electron transport chain
B	0030964	cellular_component	NADH dehydrogenase complex
B	0045271	cellular_component	respiratory chain complex I
B	0050136	molecular_function	NADH dehydrogenase (quinone) (non-electrogenic) activity
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	0003954	molecular_function	NADH dehydrogenase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005886	cellular_component	plasma membrane
C	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C	0016020	cellular_component	membrane
C	0016655	molecular_function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
C	0022904	biological_process	respiratory electron transport chain
C	0030964	cellular_component	NADH dehydrogenase complex
C	0045271	cellular_component	respiratory chain complex I
C	0050136	molecular_function	NADH dehydrogenase (quinone) (non-electrogenic) activity
C	1902600	biological_process	proton transmembrane transport
E	0003954	molecular_function	NADH dehydrogenase activity
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
E	0010181	molecular_function	FMN binding
E	0016020	cellular_component	membrane
E	0022904	biological_process	respiratory electron transport chain
E	0030964	cellular_component	NADH dehydrogenase complex
E	0045271	cellular_component	respiratory chain complex I
E	0051537	molecular_function	2 iron, 2 sulfur cluster binding
E	1902600	biological_process	proton transmembrane transport
F	0003954	molecular_function	NADH dehydrogenase activity
F	0005886	cellular_component	plasma membrane
F	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
F	0009060	biological_process	aerobic respiration
F	0010181	molecular_function	FMN binding
F	0016020	cellular_component	membrane
F	0022904	biological_process	respiratory electron transport chain
F	0030964	cellular_component	NADH dehydrogenase complex
F	0045271	cellular_component	respiratory chain complex I
F	0045333	biological_process	cellular respiration
F	0051287	molecular_function	NAD binding
F	0051539	molecular_function	4 iron, 4 sulfur cluster binding
F	1902600	biological_process	proton transmembrane transport
G	0003954	molecular_function	NADH dehydrogenase activity
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005886	cellular_component	plasma membrane
G	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
G	0009060	biological_process	aerobic respiration
G	0010181	molecular_function	FMN binding
G	0016020	cellular_component	membrane
G	0022904	biological_process	respiratory electron transport chain
G	0030964	cellular_component	NADH dehydrogenase complex
G	0045271	cellular_component	respiratory chain complex I
G	0045333	biological_process	cellular respiration
G	0051537	molecular_function	2 iron, 2 sulfur cluster binding
G	0051539	molecular_function	4 iron, 4 sulfur cluster binding
G	1902600	biological_process	proton transmembrane transport
I	0003954	molecular_function	NADH dehydrogenase activity
I	0005506	molecular_function	iron ion binding
I	0005886	cellular_component	plasma membrane
I	0009060	biological_process	aerobic respiration
I	0016020	cellular_component	membrane
I	0022904	biological_process	respiratory electron transport chain
I	0030964	cellular_component	NADH dehydrogenase complex
I	0045271	cellular_component	respiratory chain complex I
I	0050136	molecular_function	NADH dehydrogenase (quinone) (non-electrogenic) activity
I	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CvACNlCAvACP

Chain	Residue	Details
I	CYS60-PRO71
I	CYS99-PRO110

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. HHRGaEKMgErQ

Chain	Residue	Details
C	HIS252-GLN263

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREtwDLFgitfdgHpnlRrIM

Chain	Residue	Details
C	GLU138-MET159

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PyfCWhpalgsvGaCRqC

Chain	Residue	Details
G	PRO33-CYS50

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPvCEeGGnChLQ

Chain	Residue	Details
G	CYS105-GLN117

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIaCyRCVrY

Chain	Residue	Details
G	ARG152-TYR162

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGRYICGEETALINS

Chain	Residue	Details
F	GLY174-SER189

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGwCtPCRdG

Chain	Residue	Details
F	GLU349-GLY360

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DgrFTllptcCLGnCdkGP

Chain	Residue	Details
E	ASP123-PRO141

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GvDKFIPVDVYiPgCPP

Chain	Residue	Details
B	GLY144-PRO160

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01356","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	386
Details	Region: {"description":"NADH dehydrogenase I subunit D"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	76
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	81
Details	Domain: {"description":"2Fe-2S ferredoxin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00465","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	39
Details	Domain: {"description":"4Fe-4S His(Cys)3-ligated-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01184","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	56
Details	Domain: {"description":"4Fe-4S Mo/W bis-MGD-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01004","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01184","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	30
Details	Domain: {"description":"4Fe-4S ferredoxin-type 1"}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	29
Details	Domain: {"description":"4Fe-4S ferredoxin-type 2"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)