9RF2
M. tuberculosis meets European Lead Factory: identification and structural characterization of novel Rv0183 inhibitors using X-ray crystallography: ELF5
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004622 | molecular_function | phosphatidylcholine lysophospholipase activity |
A | 0005576 | cellular_component | extracellular region |
A | 0005886 | cellular_component | plasma membrane |
A | 0006629 | biological_process | lipid metabolic process |
A | 0009274 | cellular_component | peptidoglycan-based cell wall |
A | 0016020 | cellular_component | membrane |
A | 0016042 | biological_process | lipid catabolic process |
A | 0016298 | molecular_function | lipase activity |
A | 0016787 | molecular_function | hydrolase activity |
A | 0046503 | biological_process | glycerolipid catabolic process |
A | 0047372 | molecular_function | monoacylglycerol lipase activity |
A | 0052151 | biological_process | symbiont-mediated activation of host apoptosis |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"17784850","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29895832","evidenceCode":"ECO:0000305"}]} |
Chain | Residue | Details |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"17784850","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29895832","evidenceCode":"ECO:0000305"}]} |
Chain | Residue | Details |