9RD6

Crystal structure of the 4CHRD domain of human chordin with Anderson-Evans polyoxotungstate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000578	biological_process	embryonic axis specification
A	0001501	biological_process	skeletal system development
A	0001701	biological_process	in utero embryonic development
A	0002053	biological_process	positive regulation of mesenchymal cell proliferation
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0007224	biological_process	smoothened signaling pathway
A	0007389	biological_process	pattern specification process
A	0008201	molecular_function	heparin binding
A	0008283	biological_process	cell population proliferation
A	0008542	biological_process	visual learning
A	0008543	biological_process	fibroblast growth factor receptor signaling pathway
A	0009953	biological_process	dorsal/ventral pattern formation
A	0009986	cellular_component	cell surface
A	0010467	biological_process	gene expression
A	0014029	biological_process	neural crest formation
A	0014030	biological_process	mesenchymal cell fate commitment
A	0017038	biological_process	protein import
A	0019955	molecular_function	cytokine binding
A	0021513	biological_process	spinal cord dorsal/ventral patterning
A	0030336	biological_process	negative regulation of cell migration
A	0030509	biological_process	BMP signaling pathway
A	0030514	biological_process	negative regulation of BMP signaling pathway
A	0033504	biological_process	floor plate development
A	0035050	biological_process	embryonic heart tube development
A	0035640	biological_process	exploration behavior
A	0035906	biological_process	descending aorta development
A	0036122	molecular_function	BMP binding
A	0043395	molecular_function	heparan sulfate proteoglycan binding
A	0045185	biological_process	maintenance of protein location
A	0045545	molecular_function	syndecan binding
A	0045668	biological_process	negative regulation of osteoblast differentiation
A	0045785	biological_process	positive regulation of cell adhesion
A	0048168	biological_process	regulation of neuronal synaptic plasticity
A	0048663	biological_process	neuron fate commitment
A	0048731	biological_process	system development
A	0048844	biological_process	artery morphogenesis
A	0048845	biological_process	venous blood vessel morphogenesis
A	0050808	biological_process	synapse organization
A	0060291	biological_process	long-term synaptic potentiation
A	0072148	biological_process	epithelial cell fate commitment
A	0098793	cellular_component	presynapse
A	0099171	biological_process	presynaptic modulation of chemical synaptic transmission
A	0160093	biological_process	chordate pharynx development
A	0160108	biological_process	animal gross anatomical part developmental process
A	1904888	biological_process	cranial skeletal system development
A	1990926	biological_process	short-term synaptic potentiation
B	0000578	biological_process	embryonic axis specification
B	0001501	biological_process	skeletal system development
B	0001701	biological_process	in utero embryonic development
B	0002053	biological_process	positive regulation of mesenchymal cell proliferation
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0007224	biological_process	smoothened signaling pathway
B	0007389	biological_process	pattern specification process
B	0008201	molecular_function	heparin binding
B	0008283	biological_process	cell population proliferation
B	0008542	biological_process	visual learning
B	0008543	biological_process	fibroblast growth factor receptor signaling pathway
B	0009953	biological_process	dorsal/ventral pattern formation
B	0009986	cellular_component	cell surface
B	0010467	biological_process	gene expression
B	0014029	biological_process	neural crest formation
B	0014030	biological_process	mesenchymal cell fate commitment
B	0017038	biological_process	protein import
B	0019955	molecular_function	cytokine binding
B	0021513	biological_process	spinal cord dorsal/ventral patterning
B	0030336	biological_process	negative regulation of cell migration
B	0030509	biological_process	BMP signaling pathway
B	0030514	biological_process	negative regulation of BMP signaling pathway
B	0033504	biological_process	floor plate development
B	0035050	biological_process	embryonic heart tube development
B	0035640	biological_process	exploration behavior
B	0035906	biological_process	descending aorta development
B	0036122	molecular_function	BMP binding
B	0043395	molecular_function	heparan sulfate proteoglycan binding
B	0045185	biological_process	maintenance of protein location
B	0045545	molecular_function	syndecan binding
B	0045668	biological_process	negative regulation of osteoblast differentiation
B	0045785	biological_process	positive regulation of cell adhesion
B	0048168	biological_process	regulation of neuronal synaptic plasticity
B	0048663	biological_process	neuron fate commitment
B	0048731	biological_process	system development
B	0048844	biological_process	artery morphogenesis
B	0048845	biological_process	venous blood vessel morphogenesis
B	0050808	biological_process	synapse organization
B	0060291	biological_process	long-term synaptic potentiation
B	0072148	biological_process	epithelial cell fate commitment
B	0098793	cellular_component	presynapse
B	0099171	biological_process	presynaptic modulation of chemical synaptic transmission
B	0160093	biological_process	chordate pharynx development
B	0160108	biological_process	animal gross anatomical part developmental process
B	1904888	biological_process	cranial skeletal system development
B	1990926	biological_process	short-term synaptic potentiation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	240
Details	Domain: {"description":"CHRD 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00230","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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