9R8V

Cryo-EM structure of the human pre-Bact-OTS complex (whole map)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
21	0000243	cellular_component	commitment complex
21	0000244	biological_process	spliceosomal tri-snRNP complex assembly
21	0000245	biological_process	spliceosomal complex assembly
21	0000387	biological_process	spliceosomal snRNP assembly
21	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
21	0000398	biological_process	mRNA splicing, via spliceosome
21	0003723	molecular_function	RNA binding
21	0005515	molecular_function	protein binding
21	0005634	cellular_component	nucleus
21	0005654	cellular_component	nucleoplasm
21	0005681	cellular_component	spliceosomal complex
21	0005682	cellular_component	U5 snRNP
21	0005684	cellular_component	U2-type spliceosomal complex
21	0005685	cellular_component	U1 snRNP
21	0005686	cellular_component	U2 snRNP
21	0005687	cellular_component	U4 snRNP
21	0005689	cellular_component	U12-type spliceosomal complex
21	0005690	cellular_component	U4atac snRNP
21	0005829	cellular_component	cytosol
21	0008380	biological_process	RNA splicing
21	0030532	cellular_component	small nuclear ribonucleoprotein complex
21	0034693	cellular_component	U11/U12 snRNP
21	0034709	cellular_component	methylosome
21	0034715	cellular_component	pICln-Sm protein complex
21	0034719	cellular_component	SMN-Sm protein complex
21	0036261	biological_process	7-methylguanosine cap hypermethylation
21	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
21	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
21	0071001	cellular_component	U4/U6 snRNP
21	0071002	cellular_component	U4atac/U6atac snRNP
21	0071005	cellular_component	U2-type precatalytic spliceosome
21	0071006	cellular_component	U2-type catalytic step 1 spliceosome
21	0071007	cellular_component	U2-type catalytic step 2 spliceosome
21	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
21	0071011	cellular_component	precatalytic spliceosome
21	0071013	cellular_component	catalytic step 2 spliceosome
21	0071014	cellular_component	post-mRNA release spliceosomal complex
21	0071016	cellular_component	U12-type precatalytic spliceosome
21	0071018	cellular_component	U12-type catalytic step 2 spliceosome
21	0071020	cellular_component	post-spliceosomal complex
21	0097526	cellular_component	spliceosomal tri-snRNP complex
21	1903241	biological_process	U2-type prespliceosome assembly
21	1990446	molecular_function	U1 snRNP binding
22	0000244	biological_process	spliceosomal tri-snRNP complex assembly
22	0000245	biological_process	spliceosomal complex assembly
22	0000387	biological_process	spliceosomal snRNP assembly
22	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
22	0000398	biological_process	mRNA splicing, via spliceosome
22	0003723	molecular_function	RNA binding
22	0005515	molecular_function	protein binding
22	0005634	cellular_component	nucleus
22	0005654	cellular_component	nucleoplasm
22	0005681	cellular_component	spliceosomal complex
22	0005682	cellular_component	U5 snRNP
22	0005684	cellular_component	U2-type spliceosomal complex
22	0005685	cellular_component	U1 snRNP
22	0005686	cellular_component	U2 snRNP
22	0005687	cellular_component	U4 snRNP
22	0005689	cellular_component	U12-type spliceosomal complex
22	0005690	cellular_component	U4atac snRNP
22	0005829	cellular_component	cytosol
22	0008380	biological_process	RNA splicing
22	0030532	cellular_component	small nuclear ribonucleoprotein complex
22	0034693	cellular_component	U11/U12 snRNP
22	0034709	cellular_component	methylosome
22	0034715	cellular_component	pICln-Sm protein complex
22	0034719	cellular_component	SMN-Sm protein complex
22	0036261	biological_process	7-methylguanosine cap hypermethylation
22	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
22	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
22	0070062	cellular_component	extracellular exosome
22	0071001	cellular_component	U4/U6 snRNP
22	0071002	cellular_component	U4atac/U6atac snRNP
22	0071005	cellular_component	U2-type precatalytic spliceosome
22	0071006	cellular_component	U2-type catalytic step 1 spliceosome
22	0071007	cellular_component	U2-type catalytic step 2 spliceosome
22	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
22	0071011	cellular_component	precatalytic spliceosome
22	0071013	cellular_component	catalytic step 2 spliceosome
22	0071014	cellular_component	post-mRNA release spliceosomal complex
22	0071016	cellular_component	U12-type precatalytic spliceosome
22	0071018	cellular_component	U12-type catalytic step 2 spliceosome
22	0071020	cellular_component	post-spliceosomal complex
22	0097525	cellular_component	spliceosomal snRNP complex
22	1903241	biological_process	U2-type prespliceosome assembly
23	0000243	cellular_component	commitment complex
23	0000244	biological_process	spliceosomal tri-snRNP complex assembly
23	0000245	biological_process	spliceosomal complex assembly
23	0000387	biological_process	spliceosomal snRNP assembly
23	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
23	0000398	biological_process	mRNA splicing, via spliceosome
23	0003723	molecular_function	RNA binding
23	0005515	molecular_function	protein binding
23	0005634	cellular_component	nucleus
23	0005654	cellular_component	nucleoplasm
23	0005681	cellular_component	spliceosomal complex
23	0005682	cellular_component	U5 snRNP
23	0005683	cellular_component	U7 snRNP
23	0005684	cellular_component	U2-type spliceosomal complex
23	0005685	cellular_component	U1 snRNP
23	0005686	cellular_component	U2 snRNP
23	0005687	cellular_component	U4 snRNP
23	0005689	cellular_component	U12-type spliceosomal complex
23	0005690	cellular_component	U4atac snRNP
23	0005697	cellular_component	telomerase holoenzyme complex
23	0005737	cellular_component	cytoplasm
23	0005829	cellular_component	cytosol
23	0006479	biological_process	protein methylation
23	0008380	biological_process	RNA splicing
23	0016604	cellular_component	nuclear body
23	0019899	molecular_function	enzyme binding
23	0030532	cellular_component	small nuclear ribonucleoprotein complex
23	0034693	cellular_component	U11/U12 snRNP
23	0034709	cellular_component	methylosome
23	0034715	cellular_component	pICln-Sm protein complex
23	0034719	cellular_component	SMN-Sm protein complex
23	0036261	biological_process	7-methylguanosine cap hypermethylation
23	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
23	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
23	0070034	molecular_function	telomerase RNA binding
23	0071001	cellular_component	U4/U6 snRNP
23	0071002	cellular_component	U4atac/U6atac snRNP
23	0071005	cellular_component	U2-type precatalytic spliceosome
23	0071006	cellular_component	U2-type catalytic step 1 spliceosome
23	0071007	cellular_component	U2-type catalytic step 2 spliceosome
23	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
23	0071011	cellular_component	precatalytic spliceosome
23	0071013	cellular_component	catalytic step 2 spliceosome
23	0071014	cellular_component	post-mRNA release spliceosomal complex
23	0071016	cellular_component	U12-type precatalytic spliceosome
23	0071018	cellular_component	U12-type catalytic step 2 spliceosome
23	0071020	cellular_component	post-spliceosomal complex
23	0071045	biological_process	nuclear histone mRNA catabolic process
23	0071208	molecular_function	histone pre-mRNA DCP binding
23	0071209	molecular_function	U7 snRNA binding
23	0097526	cellular_component	spliceosomal tri-snRNP complex
23	1903241	biological_process	U2-type prespliceosome assembly
2A	0000387	biological_process	spliceosomal snRNP assembly
2A	0000398	biological_process	mRNA splicing, via spliceosome
2A	0003723	molecular_function	RNA binding
2A	0005515	molecular_function	protein binding
2A	0005634	cellular_component	nucleus
2A	0005654	cellular_component	nucleoplasm
2A	0005681	cellular_component	spliceosomal complex
2A	0005684	cellular_component	U2-type spliceosomal complex
2A	0005686	cellular_component	U2 snRNP
2A	0007283	biological_process	spermatogenesis
2A	0008380	biological_process	RNA splicing
2A	0016604	cellular_component	nuclear body
2A	0016607	cellular_component	nuclear speck
2A	0030532	cellular_component	small nuclear ribonucleoprotein complex
2A	0030620	molecular_function	U2 snRNA binding
2A	0071005	cellular_component	U2-type precatalytic spliceosome
2A	0071006	cellular_component	U2-type catalytic step 1 spliceosome
2A	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2A	0071011	cellular_component	precatalytic spliceosome
2A	0071013	cellular_component	catalytic step 2 spliceosome
2A	0071014	cellular_component	post-mRNA release spliceosomal complex
2A	0071020	cellular_component	post-spliceosomal complex
2A	1903241	biological_process	U2-type prespliceosome assembly
2b	0000244	biological_process	spliceosomal tri-snRNP complex assembly
2b	0000245	biological_process	spliceosomal complex assembly
2b	0000387	biological_process	spliceosomal snRNP assembly
2b	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
2b	0000398	biological_process	mRNA splicing, via spliceosome
2b	0003723	molecular_function	RNA binding
2b	0005515	molecular_function	protein binding
2b	0005634	cellular_component	nucleus
2b	0005654	cellular_component	nucleoplasm
2b	0005681	cellular_component	spliceosomal complex
2b	0005682	cellular_component	U5 snRNP
2b	0005683	cellular_component	U7 snRNP
2b	0005684	cellular_component	U2-type spliceosomal complex
2b	0005685	cellular_component	U1 snRNP
2b	0005686	cellular_component	U2 snRNP
2b	0005687	cellular_component	U4 snRNP
2b	0005689	cellular_component	U12-type spliceosomal complex
2b	0005690	cellular_component	U4atac snRNP
2b	0005697	cellular_component	telomerase holoenzyme complex
2b	0005737	cellular_component	cytoplasm
2b	0005829	cellular_component	cytosol
2b	0006479	biological_process	protein methylation
2b	0008380	biological_process	RNA splicing
2b	0030532	cellular_component	small nuclear ribonucleoprotein complex
2b	0034693	cellular_component	U11/U12 snRNP
2b	0034709	cellular_component	methylosome
2b	0034719	cellular_component	SMN-Sm protein complex
2b	0036261	biological_process	7-methylguanosine cap hypermethylation
2b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
2b	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
2b	0070034	molecular_function	telomerase RNA binding
2b	0070990	molecular_function	snRNP binding
2b	0071001	cellular_component	U4/U6 snRNP
2b	0071002	cellular_component	U4atac/U6atac snRNP
2b	0071004	cellular_component	U2-type prespliceosome
2b	0071005	cellular_component	U2-type precatalytic spliceosome
2b	0071006	cellular_component	U2-type catalytic step 1 spliceosome
2b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2b	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
2b	0071011	cellular_component	precatalytic spliceosome
2b	0071013	cellular_component	catalytic step 2 spliceosome
2b	0071014	cellular_component	post-mRNA release spliceosomal complex
2b	0071016	cellular_component	U12-type precatalytic spliceosome
2b	0071018	cellular_component	U12-type catalytic step 2 spliceosome
2b	0071020	cellular_component	post-spliceosomal complex
2b	0071045	biological_process	nuclear histone mRNA catabolic process
2b	0071204	cellular_component	histone pre-mRNA 3'end processing complex
2b	0071208	molecular_function	histone pre-mRNA DCP binding
2b	1903241	biological_process	U2-type prespliceosome assembly
2b	1990446	molecular_function	U1 snRNP binding
2b	1990447	molecular_function	U2 snRNP binding
2B	0000387	biological_process	spliceosomal snRNP assembly
2B	0000398	biological_process	mRNA splicing, via spliceosome
2B	0005515	molecular_function	protein binding
2B	0005634	cellular_component	nucleus
2B	0005654	cellular_component	nucleoplasm
2B	0005681	cellular_component	spliceosomal complex
2B	0005684	cellular_component	U2-type spliceosomal complex
2B	0005685	cellular_component	U1 snRNP
2B	0005686	cellular_component	U2 snRNP
2B	0016607	cellular_component	nuclear speck
2B	0030619	molecular_function	U1 snRNA binding
2B	0071005	cellular_component	U2-type precatalytic spliceosome
2B	0071006	cellular_component	U2-type catalytic step 1 spliceosome
2B	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2B	0071011	cellular_component	precatalytic spliceosome
2B	0071013	cellular_component	catalytic step 2 spliceosome
2B	0071014	cellular_component	post-mRNA release spliceosomal complex
2B	0071020	cellular_component	post-spliceosomal complex
2B	0097525	cellular_component	spliceosomal snRNP complex
2B	1903241	biological_process	U2-type prespliceosome assembly
2e	0000244	biological_process	spliceosomal tri-snRNP complex assembly
2e	0000245	biological_process	spliceosomal complex assembly
2e	0000387	biological_process	spliceosomal snRNP assembly
2e	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
2e	0000398	biological_process	mRNA splicing, via spliceosome
2e	0005515	molecular_function	protein binding
2e	0005634	cellular_component	nucleus
2e	0005654	cellular_component	nucleoplasm
2e	0005681	cellular_component	spliceosomal complex
2e	0005682	cellular_component	U5 snRNP
2e	0005683	cellular_component	U7 snRNP
2e	0005684	cellular_component	U2-type spliceosomal complex
2e	0005685	cellular_component	U1 snRNP
2e	0005686	cellular_component	U2 snRNP
2e	0005687	cellular_component	U4 snRNP
2e	0005689	cellular_component	U12-type spliceosomal complex
2e	0005690	cellular_component	U4atac snRNP
2e	0005697	cellular_component	telomerase holoenzyme complex
2e	0005829	cellular_component	cytosol
2e	0030532	cellular_component	small nuclear ribonucleoprotein complex
2e	0034693	cellular_component	U11/U12 snRNP
2e	0034709	cellular_component	methylosome
2e	0034715	cellular_component	pICln-Sm protein complex
2e	0034719	cellular_component	SMN-Sm protein complex
2e	0036261	biological_process	7-methylguanosine cap hypermethylation
2e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
2e	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
2e	0071001	cellular_component	U4/U6 snRNP
2e	0071002	cellular_component	U4atac/U6atac snRNP
2e	0071005	cellular_component	U2-type precatalytic spliceosome
2e	0071006	cellular_component	U2-type catalytic step 1 spliceosome
2e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2e	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
2e	0071011	cellular_component	precatalytic spliceosome
2e	0071013	cellular_component	catalytic step 2 spliceosome
2e	0071014	cellular_component	post-mRNA release spliceosomal complex
2e	0071016	cellular_component	U12-type precatalytic spliceosome
2e	0071018	cellular_component	U12-type catalytic step 2 spliceosome
2e	0071020	cellular_component	post-spliceosomal complex
2e	0071045	biological_process	nuclear histone mRNA catabolic process
2e	1903241	biological_process	U2-type prespliceosome assembly
2f	0000244	biological_process	spliceosomal tri-snRNP complex assembly
2f	0000245	biological_process	spliceosomal complex assembly
2f	0000387	biological_process	spliceosomal snRNP assembly
2f	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
2f	0000398	biological_process	mRNA splicing, via spliceosome
2f	0003723	molecular_function	RNA binding
2f	0005515	molecular_function	protein binding
2f	0005634	cellular_component	nucleus
2f	0005654	cellular_component	nucleoplasm
2f	0005681	cellular_component	spliceosomal complex
2f	0005682	cellular_component	U5 snRNP
2f	0005683	cellular_component	U7 snRNP
2f	0005684	cellular_component	U2-type spliceosomal complex
2f	0005685	cellular_component	U1 snRNP
2f	0005686	cellular_component	U2 snRNP
2f	0005687	cellular_component	U4 snRNP
2f	0005689	cellular_component	U12-type spliceosomal complex
2f	0005690	cellular_component	U4atac snRNP
2f	0005829	cellular_component	cytosol
2f	0008380	biological_process	RNA splicing
2f	0022618	biological_process	protein-RNA complex assembly
2f	0030532	cellular_component	small nuclear ribonucleoprotein complex
2f	0034693	cellular_component	U11/U12 snRNP
2f	0034709	cellular_component	methylosome
2f	0034715	cellular_component	pICln-Sm protein complex
2f	0034719	cellular_component	SMN-Sm protein complex
2f	0036261	biological_process	7-methylguanosine cap hypermethylation
2f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
2f	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
2f	0071001	cellular_component	U4/U6 snRNP
2f	0071002	cellular_component	U4atac/U6atac snRNP
2f	0071005	cellular_component	U2-type precatalytic spliceosome
2f	0071006	cellular_component	U2-type catalytic step 1 spliceosome
2f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2f	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
2f	0071011	cellular_component	precatalytic spliceosome
2f	0071013	cellular_component	catalytic step 2 spliceosome
2f	0071014	cellular_component	post-mRNA release spliceosomal complex
2f	0071016	cellular_component	U12-type precatalytic spliceosome
2f	0071018	cellular_component	U12-type catalytic step 2 spliceosome
2f	0071020	cellular_component	post-spliceosomal complex
2f	0071045	biological_process	nuclear histone mRNA catabolic process
2f	1903241	biological_process	U2-type prespliceosome assembly
2g	0000244	biological_process	spliceosomal tri-snRNP complex assembly
2g	0000245	biological_process	spliceosomal complex assembly
2g	0000387	biological_process	spliceosomal snRNP assembly
2g	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
2g	0000398	biological_process	mRNA splicing, via spliceosome
2g	0003723	molecular_function	RNA binding
2g	0005515	molecular_function	protein binding
2g	0005634	cellular_component	nucleus
2g	0005654	cellular_component	nucleoplasm
2g	0005681	cellular_component	spliceosomal complex
2g	0005682	cellular_component	U5 snRNP
2g	0005683	cellular_component	U7 snRNP
2g	0005684	cellular_component	U2-type spliceosomal complex
2g	0005685	cellular_component	U1 snRNP
2g	0005686	cellular_component	U2 snRNP
2g	0005687	cellular_component	U4 snRNP
2g	0005689	cellular_component	U12-type spliceosomal complex
2g	0005690	cellular_component	U4atac snRNP
2g	0005829	cellular_component	cytosol
2g	0008380	biological_process	RNA splicing
2g	0030532	cellular_component	small nuclear ribonucleoprotein complex
2g	0034693	cellular_component	U11/U12 snRNP
2g	0034709	cellular_component	methylosome
2g	0034719	cellular_component	SMN-Sm protein complex
2g	0036261	biological_process	7-methylguanosine cap hypermethylation
2g	0043186	cellular_component	P granule
2g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
2g	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
2g	0071001	cellular_component	U4/U6 snRNP
2g	0071002	cellular_component	U4atac/U6atac snRNP
2g	0071004	cellular_component	U2-type prespliceosome
2g	0071005	cellular_component	U2-type precatalytic spliceosome
2g	0071006	cellular_component	U2-type catalytic step 1 spliceosome
2g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2g	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
2g	0071011	cellular_component	precatalytic spliceosome
2g	0071013	cellular_component	catalytic step 2 spliceosome
2g	0071014	cellular_component	post-mRNA release spliceosomal complex
2g	0071016	cellular_component	U12-type precatalytic spliceosome
2g	0071018	cellular_component	U12-type catalytic step 2 spliceosome
2g	0071020	cellular_component	post-spliceosomal complex
2g	0071045	biological_process	nuclear histone mRNA catabolic process
2g	0097526	cellular_component	spliceosomal tri-snRNP complex
2g	1903241	biological_process	U2-type prespliceosome assembly
51	0000243	cellular_component	commitment complex
51	0000244	biological_process	spliceosomal tri-snRNP complex assembly
51	0000245	biological_process	spliceosomal complex assembly
51	0000387	biological_process	spliceosomal snRNP assembly
51	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
51	0000398	biological_process	mRNA splicing, via spliceosome
51	0003723	molecular_function	RNA binding
51	0005515	molecular_function	protein binding
51	0005634	cellular_component	nucleus
51	0005654	cellular_component	nucleoplasm
51	0005681	cellular_component	spliceosomal complex
51	0005682	cellular_component	U5 snRNP
51	0005684	cellular_component	U2-type spliceosomal complex
51	0005685	cellular_component	U1 snRNP
51	0005686	cellular_component	U2 snRNP
51	0005687	cellular_component	U4 snRNP
51	0005689	cellular_component	U12-type spliceosomal complex
51	0005690	cellular_component	U4atac snRNP
51	0005829	cellular_component	cytosol
51	0008380	biological_process	RNA splicing
51	0030532	cellular_component	small nuclear ribonucleoprotein complex
51	0034693	cellular_component	U11/U12 snRNP
51	0034709	cellular_component	methylosome
51	0034715	cellular_component	pICln-Sm protein complex
51	0034719	cellular_component	SMN-Sm protein complex
51	0036261	biological_process	7-methylguanosine cap hypermethylation
51	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
51	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
51	0071001	cellular_component	U4/U6 snRNP
51	0071002	cellular_component	U4atac/U6atac snRNP
51	0071005	cellular_component	U2-type precatalytic spliceosome
51	0071006	cellular_component	U2-type catalytic step 1 spliceosome
51	0071007	cellular_component	U2-type catalytic step 2 spliceosome
51	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
51	0071011	cellular_component	precatalytic spliceosome
51	0071013	cellular_component	catalytic step 2 spliceosome
51	0071014	cellular_component	post-mRNA release spliceosomal complex
51	0071016	cellular_component	U12-type precatalytic spliceosome
51	0071018	cellular_component	U12-type catalytic step 2 spliceosome
51	0071020	cellular_component	post-spliceosomal complex
51	0097526	cellular_component	spliceosomal tri-snRNP complex
51	1903241	biological_process	U2-type prespliceosome assembly
51	1990446	molecular_function	U1 snRNP binding
52	0000244	biological_process	spliceosomal tri-snRNP complex assembly
52	0000245	biological_process	spliceosomal complex assembly
52	0000387	biological_process	spliceosomal snRNP assembly
52	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
52	0000398	biological_process	mRNA splicing, via spliceosome
52	0003723	molecular_function	RNA binding
52	0005515	molecular_function	protein binding
52	0005634	cellular_component	nucleus
52	0005654	cellular_component	nucleoplasm
52	0005681	cellular_component	spliceosomal complex
52	0005682	cellular_component	U5 snRNP
52	0005684	cellular_component	U2-type spliceosomal complex
52	0005685	cellular_component	U1 snRNP
52	0005686	cellular_component	U2 snRNP
52	0005687	cellular_component	U4 snRNP
52	0005689	cellular_component	U12-type spliceosomal complex
52	0005690	cellular_component	U4atac snRNP
52	0005829	cellular_component	cytosol
52	0008380	biological_process	RNA splicing
52	0030532	cellular_component	small nuclear ribonucleoprotein complex
52	0034693	cellular_component	U11/U12 snRNP
52	0034709	cellular_component	methylosome
52	0034715	cellular_component	pICln-Sm protein complex
52	0034719	cellular_component	SMN-Sm protein complex
52	0036261	biological_process	7-methylguanosine cap hypermethylation
52	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
52	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
52	0070062	cellular_component	extracellular exosome
52	0071001	cellular_component	U4/U6 snRNP
52	0071002	cellular_component	U4atac/U6atac snRNP
52	0071005	cellular_component	U2-type precatalytic spliceosome
52	0071006	cellular_component	U2-type catalytic step 1 spliceosome
52	0071007	cellular_component	U2-type catalytic step 2 spliceosome
52	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
52	0071011	cellular_component	precatalytic spliceosome
52	0071013	cellular_component	catalytic step 2 spliceosome
52	0071014	cellular_component	post-mRNA release spliceosomal complex
52	0071016	cellular_component	U12-type precatalytic spliceosome
52	0071018	cellular_component	U12-type catalytic step 2 spliceosome
52	0071020	cellular_component	post-spliceosomal complex
52	0097525	cellular_component	spliceosomal snRNP complex
52	1903241	biological_process	U2-type prespliceosome assembly
53	0000243	cellular_component	commitment complex
53	0000244	biological_process	spliceosomal tri-snRNP complex assembly
53	0000245	biological_process	spliceosomal complex assembly
53	0000387	biological_process	spliceosomal snRNP assembly
53	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
53	0000398	biological_process	mRNA splicing, via spliceosome
53	0003723	molecular_function	RNA binding
53	0005515	molecular_function	protein binding
53	0005634	cellular_component	nucleus
53	0005654	cellular_component	nucleoplasm
53	0005681	cellular_component	spliceosomal complex
53	0005682	cellular_component	U5 snRNP
53	0005683	cellular_component	U7 snRNP
53	0005684	cellular_component	U2-type spliceosomal complex
53	0005685	cellular_component	U1 snRNP
53	0005686	cellular_component	U2 snRNP
53	0005687	cellular_component	U4 snRNP
53	0005689	cellular_component	U12-type spliceosomal complex
53	0005690	cellular_component	U4atac snRNP
53	0005697	cellular_component	telomerase holoenzyme complex
53	0005737	cellular_component	cytoplasm
53	0005829	cellular_component	cytosol
53	0006479	biological_process	protein methylation
53	0008380	biological_process	RNA splicing
53	0016604	cellular_component	nuclear body
53	0019899	molecular_function	enzyme binding
53	0030532	cellular_component	small nuclear ribonucleoprotein complex
53	0034693	cellular_component	U11/U12 snRNP
53	0034709	cellular_component	methylosome
53	0034715	cellular_component	pICln-Sm protein complex
53	0034719	cellular_component	SMN-Sm protein complex
53	0036261	biological_process	7-methylguanosine cap hypermethylation
53	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
53	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
53	0070034	molecular_function	telomerase RNA binding
53	0071001	cellular_component	U4/U6 snRNP
53	0071002	cellular_component	U4atac/U6atac snRNP
53	0071005	cellular_component	U2-type precatalytic spliceosome
53	0071006	cellular_component	U2-type catalytic step 1 spliceosome
53	0071007	cellular_component	U2-type catalytic step 2 spliceosome
53	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
53	0071011	cellular_component	precatalytic spliceosome
53	0071013	cellular_component	catalytic step 2 spliceosome
53	0071014	cellular_component	post-mRNA release spliceosomal complex
53	0071016	cellular_component	U12-type precatalytic spliceosome
53	0071018	cellular_component	U12-type catalytic step 2 spliceosome
53	0071020	cellular_component	post-spliceosomal complex
53	0071045	biological_process	nuclear histone mRNA catabolic process
53	0071208	molecular_function	histone pre-mRNA DCP binding
53	0071209	molecular_function	U7 snRNA binding
53	0097526	cellular_component	spliceosomal tri-snRNP complex
53	1903241	biological_process	U2-type prespliceosome assembly
5A	0000387	biological_process	spliceosomal snRNP assembly
5A	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
5A	0000398	biological_process	mRNA splicing, via spliceosome
5A	0003723	molecular_function	RNA binding
5A	0005515	molecular_function	protein binding
5A	0005634	cellular_component	nucleus
5A	0005654	cellular_component	nucleoplasm
5A	0005681	cellular_component	spliceosomal complex
5A	0005684	cellular_component	U2-type spliceosomal complex
5A	0005686	cellular_component	U2 snRNP
5A	0005689	cellular_component	U12-type spliceosomal complex
5A	0008270	molecular_function	zinc ion binding
5A	0016363	cellular_component	nuclear matrix
5A	0016607	cellular_component	nuclear speck
5A	0045893	biological_process	positive regulation of DNA-templated transcription
5A	0048863	biological_process	stem cell differentiation
5A	0071005	cellular_component	U2-type precatalytic spliceosome
5A	0071006	cellular_component	U2-type catalytic step 1 spliceosome
5A	0071011	cellular_component	precatalytic spliceosome
5A	0071013	cellular_component	catalytic step 2 spliceosome
5A	0071016	cellular_component	U12-type precatalytic spliceosome
5A	0071018	cellular_component	U12-type catalytic step 2 spliceosome
5A	1903241	biological_process	U2-type prespliceosome assembly
5b	0000244	biological_process	spliceosomal tri-snRNP complex assembly
5b	0000245	biological_process	spliceosomal complex assembly
5b	0000387	biological_process	spliceosomal snRNP assembly
5b	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
5b	0000398	biological_process	mRNA splicing, via spliceosome
5b	0003723	molecular_function	RNA binding
5b	0005515	molecular_function	protein binding
5b	0005634	cellular_component	nucleus
5b	0005654	cellular_component	nucleoplasm
5b	0005681	cellular_component	spliceosomal complex
5b	0005682	cellular_component	U5 snRNP
5b	0005683	cellular_component	U7 snRNP
5b	0005684	cellular_component	U2-type spliceosomal complex
5b	0005685	cellular_component	U1 snRNP
5b	0005686	cellular_component	U2 snRNP
5b	0005687	cellular_component	U4 snRNP
5b	0005689	cellular_component	U12-type spliceosomal complex
5b	0005690	cellular_component	U4atac snRNP
5b	0005697	cellular_component	telomerase holoenzyme complex
5b	0005737	cellular_component	cytoplasm
5b	0005829	cellular_component	cytosol
5b	0006479	biological_process	protein methylation
5b	0008380	biological_process	RNA splicing
5b	0030532	cellular_component	small nuclear ribonucleoprotein complex
5b	0034693	cellular_component	U11/U12 snRNP
5b	0034709	cellular_component	methylosome
5b	0034719	cellular_component	SMN-Sm protein complex
5b	0036261	biological_process	7-methylguanosine cap hypermethylation
5b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
5b	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
5b	0070034	molecular_function	telomerase RNA binding
5b	0070990	molecular_function	snRNP binding
5b	0071001	cellular_component	U4/U6 snRNP
5b	0071002	cellular_component	U4atac/U6atac snRNP
5b	0071004	cellular_component	U2-type prespliceosome
5b	0071005	cellular_component	U2-type precatalytic spliceosome
5b	0071006	cellular_component	U2-type catalytic step 1 spliceosome
5b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
5b	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
5b	0071011	cellular_component	precatalytic spliceosome
5b	0071013	cellular_component	catalytic step 2 spliceosome
5b	0071014	cellular_component	post-mRNA release spliceosomal complex
5b	0071016	cellular_component	U12-type precatalytic spliceosome
5b	0071018	cellular_component	U12-type catalytic step 2 spliceosome
5b	0071020	cellular_component	post-spliceosomal complex
5b	0071045	biological_process	nuclear histone mRNA catabolic process
5b	0071204	cellular_component	histone pre-mRNA 3'end processing complex
5b	0071208	molecular_function	histone pre-mRNA DCP binding
5b	1903241	biological_process	U2-type prespliceosome assembly
5b	1990446	molecular_function	U1 snRNP binding
5b	1990447	molecular_function	U2 snRNP binding
5e	0000244	biological_process	spliceosomal tri-snRNP complex assembly
5e	0000245	biological_process	spliceosomal complex assembly
5e	0000387	biological_process	spliceosomal snRNP assembly
5e	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
5e	0000398	biological_process	mRNA splicing, via spliceosome
5e	0005515	molecular_function	protein binding
5e	0005634	cellular_component	nucleus
5e	0005654	cellular_component	nucleoplasm
5e	0005681	cellular_component	spliceosomal complex
5e	0005682	cellular_component	U5 snRNP
5e	0005683	cellular_component	U7 snRNP
5e	0005684	cellular_component	U2-type spliceosomal complex
5e	0005685	cellular_component	U1 snRNP
5e	0005686	cellular_component	U2 snRNP
5e	0005687	cellular_component	U4 snRNP
5e	0005689	cellular_component	U12-type spliceosomal complex
5e	0005690	cellular_component	U4atac snRNP
5e	0005697	cellular_component	telomerase holoenzyme complex
5e	0005829	cellular_component	cytosol
5e	0030532	cellular_component	small nuclear ribonucleoprotein complex
5e	0034693	cellular_component	U11/U12 snRNP
5e	0034709	cellular_component	methylosome
5e	0034715	cellular_component	pICln-Sm protein complex
5e	0034719	cellular_component	SMN-Sm protein complex
5e	0036261	biological_process	7-methylguanosine cap hypermethylation
5e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
5e	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
5e	0071001	cellular_component	U4/U6 snRNP
5e	0071002	cellular_component	U4atac/U6atac snRNP
5e	0071005	cellular_component	U2-type precatalytic spliceosome
5e	0071006	cellular_component	U2-type catalytic step 1 spliceosome
5e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
5e	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
5e	0071011	cellular_component	precatalytic spliceosome
5e	0071013	cellular_component	catalytic step 2 spliceosome
5e	0071014	cellular_component	post-mRNA release spliceosomal complex
5e	0071016	cellular_component	U12-type precatalytic spliceosome
5e	0071018	cellular_component	U12-type catalytic step 2 spliceosome
5e	0071020	cellular_component	post-spliceosomal complex
5e	0071045	biological_process	nuclear histone mRNA catabolic process
5e	1903241	biological_process	U2-type prespliceosome assembly
5f	0000244	biological_process	spliceosomal tri-snRNP complex assembly
5f	0000245	biological_process	spliceosomal complex assembly
5f	0000387	biological_process	spliceosomal snRNP assembly
5f	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
5f	0000398	biological_process	mRNA splicing, via spliceosome
5f	0003723	molecular_function	RNA binding
5f	0005515	molecular_function	protein binding
5f	0005634	cellular_component	nucleus
5f	0005654	cellular_component	nucleoplasm
5f	0005681	cellular_component	spliceosomal complex
5f	0005682	cellular_component	U5 snRNP
5f	0005683	cellular_component	U7 snRNP
5f	0005684	cellular_component	U2-type spliceosomal complex
5f	0005685	cellular_component	U1 snRNP
5f	0005686	cellular_component	U2 snRNP
5f	0005687	cellular_component	U4 snRNP
5f	0005689	cellular_component	U12-type spliceosomal complex
5f	0005690	cellular_component	U4atac snRNP
5f	0005829	cellular_component	cytosol
5f	0008380	biological_process	RNA splicing
5f	0022618	biological_process	protein-RNA complex assembly
5f	0030532	cellular_component	small nuclear ribonucleoprotein complex
5f	0034693	cellular_component	U11/U12 snRNP
5f	0034709	cellular_component	methylosome
5f	0034715	cellular_component	pICln-Sm protein complex
5f	0034719	cellular_component	SMN-Sm protein complex
5f	0036261	biological_process	7-methylguanosine cap hypermethylation
5f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
5f	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
5f	0071001	cellular_component	U4/U6 snRNP
5f	0071002	cellular_component	U4atac/U6atac snRNP
5f	0071005	cellular_component	U2-type precatalytic spliceosome
5f	0071006	cellular_component	U2-type catalytic step 1 spliceosome
5f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
5f	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
5f	0071011	cellular_component	precatalytic spliceosome
5f	0071013	cellular_component	catalytic step 2 spliceosome
5f	0071014	cellular_component	post-mRNA release spliceosomal complex
5f	0071016	cellular_component	U12-type precatalytic spliceosome
5f	0071018	cellular_component	U12-type catalytic step 2 spliceosome
5f	0071020	cellular_component	post-spliceosomal complex
5f	0071045	biological_process	nuclear histone mRNA catabolic process
5f	1903241	biological_process	U2-type prespliceosome assembly
5g	0000244	biological_process	spliceosomal tri-snRNP complex assembly
5g	0000245	biological_process	spliceosomal complex assembly
5g	0000387	biological_process	spliceosomal snRNP assembly
5g	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
5g	0000398	biological_process	mRNA splicing, via spliceosome
5g	0003723	molecular_function	RNA binding
5g	0005515	molecular_function	protein binding
5g	0005634	cellular_component	nucleus
5g	0005654	cellular_component	nucleoplasm
5g	0005681	cellular_component	spliceosomal complex
5g	0005682	cellular_component	U5 snRNP
5g	0005683	cellular_component	U7 snRNP
5g	0005684	cellular_component	U2-type spliceosomal complex
5g	0005685	cellular_component	U1 snRNP
5g	0005686	cellular_component	U2 snRNP
5g	0005687	cellular_component	U4 snRNP
5g	0005689	cellular_component	U12-type spliceosomal complex
5g	0005690	cellular_component	U4atac snRNP
5g	0005829	cellular_component	cytosol
5g	0008380	biological_process	RNA splicing
5g	0030532	cellular_component	small nuclear ribonucleoprotein complex
5g	0034693	cellular_component	U11/U12 snRNP
5g	0034709	cellular_component	methylosome
5g	0034719	cellular_component	SMN-Sm protein complex
5g	0036261	biological_process	7-methylguanosine cap hypermethylation
5g	0043186	cellular_component	P granule
5g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
5g	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
5g	0071001	cellular_component	U4/U6 snRNP
5g	0071002	cellular_component	U4atac/U6atac snRNP
5g	0071004	cellular_component	U2-type prespliceosome
5g	0071005	cellular_component	U2-type precatalytic spliceosome
5g	0071006	cellular_component	U2-type catalytic step 1 spliceosome
5g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
5g	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
5g	0071011	cellular_component	precatalytic spliceosome
5g	0071013	cellular_component	catalytic step 2 spliceosome
5g	0071014	cellular_component	post-mRNA release spliceosomal complex
5g	0071016	cellular_component	U12-type precatalytic spliceosome
5g	0071018	cellular_component	U12-type catalytic step 2 spliceosome
5g	0071020	cellular_component	post-spliceosomal complex
5g	0071045	biological_process	nuclear histone mRNA catabolic process
5g	0097526	cellular_component	spliceosomal tri-snRNP complex
5g	1903241	biological_process	U2-type prespliceosome assembly
62	0000244	biological_process	spliceosomal tri-snRNP complex assembly
62	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
62	0000387	biological_process	spliceosomal snRNP assembly
62	0000398	biological_process	mRNA splicing, via spliceosome
62	0003723	molecular_function	RNA binding
62	0005515	molecular_function	protein binding
62	0005634	cellular_component	nucleus
62	0005654	cellular_component	nucleoplasm
62	0005681	cellular_component	spliceosomal complex
62	0005688	cellular_component	U6 snRNP
62	0005691	cellular_component	U6atac snRNP
62	0005737	cellular_component	cytoplasm
62	0005829	cellular_component	cytosol
62	0006402	biological_process	mRNA catabolic process
62	0017070	molecular_function	U6 snRNA binding
62	0030620	molecular_function	U2 snRNA binding
62	0031267	molecular_function	small GTPase binding
62	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
62	0071001	cellular_component	U4/U6 snRNP
62	0071002	cellular_component	U4atac/U6atac snRNP
62	0071005	cellular_component	U2-type precatalytic spliceosome
62	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
62	0071011	cellular_component	precatalytic spliceosome
62	0071013	cellular_component	catalytic step 2 spliceosome
62	0120115	cellular_component	Lsm2-8 complex
62	1990726	cellular_component	Lsm1-7-Pat1 complex
63	0000244	biological_process	spliceosomal tri-snRNP complex assembly
63	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
63	0000387	biological_process	spliceosomal snRNP assembly
63	0000398	biological_process	mRNA splicing, via spliceosome
63	0000932	cellular_component	P-body
63	0003723	molecular_function	RNA binding
63	0005515	molecular_function	protein binding
63	0005634	cellular_component	nucleus
63	0005654	cellular_component	nucleoplasm
63	0005681	cellular_component	spliceosomal complex
63	0005691	cellular_component	U6atac snRNP
63	0005737	cellular_component	cytoplasm
63	0005829	cellular_component	cytosol
63	0006397	biological_process	mRNA processing
63	0030629	molecular_function	U6 snRNA 3'-end binding
63	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
63	0071001	cellular_component	U4/U6 snRNP
63	0071002	cellular_component	U4atac/U6atac snRNP
63	0071005	cellular_component	U2-type precatalytic spliceosome
63	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
63	0071011	cellular_component	precatalytic spliceosome
63	0071013	cellular_component	catalytic step 2 spliceosome
63	0120115	cellular_component	Lsm2-8 complex
63	1990726	cellular_component	Lsm1-7-Pat1 complex
64	0000244	biological_process	spliceosomal tri-snRNP complex assembly
64	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
64	0000387	biological_process	spliceosomal snRNP assembly
64	0000398	biological_process	mRNA splicing, via spliceosome
64	0000932	cellular_component	P-body
64	0003723	molecular_function	RNA binding
64	0005515	molecular_function	protein binding
64	0005634	cellular_component	nucleus
64	0005654	cellular_component	nucleoplasm
64	0005681	cellular_component	spliceosomal complex
64	0005688	cellular_component	U6 snRNP
64	0005691	cellular_component	U6atac snRNP
64	0005737	cellular_component	cytoplasm
64	0005829	cellular_component	cytosol
64	0008380	biological_process	RNA splicing
64	0016020	cellular_component	membrane
64	0017070	molecular_function	U6 snRNA binding
64	0032991	cellular_component	protein-containing complex
64	0033962	biological_process	P-body assembly
64	0042731	molecular_function	PH domain binding
64	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
64	0071001	cellular_component	U4/U6 snRNP
64	0071002	cellular_component	U4atac/U6atac snRNP
64	0071005	cellular_component	U2-type precatalytic spliceosome
64	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
64	0071011	cellular_component	precatalytic spliceosome
64	0097526	cellular_component	spliceosomal tri-snRNP complex
64	0120115	cellular_component	Lsm2-8 complex
65	0000244	biological_process	spliceosomal tri-snRNP complex assembly
65	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
65	0000387	biological_process	spliceosomal snRNP assembly
65	0000398	biological_process	mRNA splicing, via spliceosome
65	0003723	molecular_function	RNA binding
65	0005515	molecular_function	protein binding
65	0005634	cellular_component	nucleus
65	0005654	cellular_component	nucleoplasm
65	0005681	cellular_component	spliceosomal complex
65	0005688	cellular_component	U6 snRNP
65	0005691	cellular_component	U6atac snRNP
65	0005737	cellular_component	cytoplasm
65	0005829	cellular_component	cytosol
65	0006397	biological_process	mRNA processing
65	0006402	biological_process	mRNA catabolic process
65	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
65	0046982	molecular_function	protein heterodimerization activity
65	0071001	cellular_component	U4/U6 snRNP
65	0071002	cellular_component	U4atac/U6atac snRNP
65	0071005	cellular_component	U2-type precatalytic spliceosome
65	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
65	0071011	cellular_component	precatalytic spliceosome
65	0120115	cellular_component	Lsm2-8 complex
65	1990726	cellular_component	Lsm1-7-Pat1 complex
66	0000244	biological_process	spliceosomal tri-snRNP complex assembly
66	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
66	0000387	biological_process	spliceosomal snRNP assembly
66	0000398	biological_process	mRNA splicing, via spliceosome
66	0000932	cellular_component	P-body
66	0003723	molecular_function	RNA binding
66	0005515	molecular_function	protein binding
66	0005634	cellular_component	nucleus
66	0005654	cellular_component	nucleoplasm
66	0005681	cellular_component	spliceosomal complex
66	0005688	cellular_component	U6 snRNP
66	0005691	cellular_component	U6atac snRNP
66	0005730	cellular_component	nucleolus
66	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
66	0005737	cellular_component	cytoplasm
66	0005829	cellular_component	cytosol
66	0006402	biological_process	mRNA catabolic process
66	0008380	biological_process	RNA splicing
66	0030490	biological_process	maturation of SSU-rRNA
66	0030532	cellular_component	small nuclear ribonucleoprotein complex
66	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
66	0046982	molecular_function	protein heterodimerization activity
66	0071001	cellular_component	U4/U6 snRNP
66	0071002	cellular_component	U4atac/U6atac snRNP
66	0071005	cellular_component	U2-type precatalytic spliceosome
66	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
66	0071011	cellular_component	precatalytic spliceosome
66	0120115	cellular_component	Lsm2-8 complex
67	0000244	biological_process	spliceosomal tri-snRNP complex assembly
67	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
67	0000387	biological_process	spliceosomal snRNP assembly
67	0000398	biological_process	mRNA splicing, via spliceosome
67	0003723	molecular_function	RNA binding
67	0005515	molecular_function	protein binding
67	0005634	cellular_component	nucleus
67	0005654	cellular_component	nucleoplasm
67	0005681	cellular_component	spliceosomal complex
67	0005688	cellular_component	U6 snRNP
67	0005689	cellular_component	U12-type spliceosomal complex
67	0005691	cellular_component	U6atac snRNP
67	0005737	cellular_component	cytoplasm
67	0005829	cellular_component	cytosol
67	0017070	molecular_function	U6 snRNA binding
67	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
67	0071001	cellular_component	U4/U6 snRNP
67	0071002	cellular_component	U4atac/U6atac snRNP
67	0071004	cellular_component	U2-type prespliceosome
67	0071005	cellular_component	U2-type precatalytic spliceosome
67	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
67	0071011	cellular_component	precatalytic spliceosome
67	0071013	cellular_component	catalytic step 2 spliceosome
67	0097526	cellular_component	spliceosomal tri-snRNP complex
67	0120115	cellular_component	Lsm2-8 complex
67	1990726	cellular_component	Lsm1-7-Pat1 complex
68	0000244	biological_process	spliceosomal tri-snRNP complex assembly
68	0000387	biological_process	spliceosomal snRNP assembly
68	0000398	biological_process	mRNA splicing, via spliceosome
68	0003723	molecular_function	RNA binding
68	0003729	molecular_function	mRNA binding
68	0005515	molecular_function	protein binding
68	0005634	cellular_component	nucleus
68	0005654	cellular_component	nucleoplasm
68	0005681	cellular_component	spliceosomal complex
68	0005688	cellular_component	U6 snRNP
68	0005691	cellular_component	U6atac snRNP
68	0017070	molecular_function	U6 snRNA binding
68	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
68	0071001	cellular_component	U4/U6 snRNP
68	0071002	cellular_component	U4atac/U6atac snRNP
68	0071005	cellular_component	U2-type precatalytic spliceosome
68	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
68	0071011	cellular_component	precatalytic spliceosome
68	0120115	cellular_component	Lsm2-8 complex
7	0000387	biological_process	spliceosomal snRNP assembly
7	0000389	biological_process	mRNA 3'-splice site recognition
7	0000398	biological_process	mRNA splicing, via spliceosome
7	0003723	molecular_function	RNA binding
7	0005515	molecular_function	protein binding
7	0005634	cellular_component	nucleus
7	0005654	cellular_component	nucleoplasm
7	0005681	cellular_component	spliceosomal complex
7	0005684	cellular_component	U2-type spliceosomal complex
7	0005686	cellular_component	U2 snRNP
7	0006397	biological_process	mRNA processing
7	0016607	cellular_component	nuclear speck
7	0045292	biological_process	mRNA cis splicing, via spliceosome
7	0071004	cellular_component	U2-type prespliceosome
7	0071005	cellular_component	U2-type precatalytic spliceosome
7	0071006	cellular_component	U2-type catalytic step 1 spliceosome
7	0071011	cellular_component	precatalytic spliceosome
7	0071013	cellular_component	catalytic step 2 spliceosome
7	1903241	biological_process	U2-type prespliceosome assembly
8	0000387	biological_process	spliceosomal snRNP assembly
8	0000389	biological_process	mRNA 3'-splice site recognition
8	0000398	biological_process	mRNA splicing, via spliceosome
8	0003723	molecular_function	RNA binding
8	0005515	molecular_function	protein binding
8	0005634	cellular_component	nucleus
8	0005654	cellular_component	nucleoplasm
8	0005681	cellular_component	spliceosomal complex
8	0005684	cellular_component	U2-type spliceosomal complex
8	0005686	cellular_component	U2 snRNP
8	0006397	biological_process	mRNA processing
8	0010976	biological_process	positive regulation of neuron projection development
8	0016607	cellular_component	nuclear speck
8	0071004	cellular_component	U2-type prespliceosome
8	0071005	cellular_component	U2-type precatalytic spliceosome
8	0071006	cellular_component	U2-type catalytic step 1 spliceosome
8	0071011	cellular_component	precatalytic spliceosome
8	0071013	cellular_component	catalytic step 2 spliceosome
8	1903241	biological_process	U2-type prespliceosome assembly
9	0000375	biological_process	RNA splicing, via transesterification reactions
9	0000387	biological_process	spliceosomal snRNP assembly
9	0000389	biological_process	mRNA 3'-splice site recognition
9	0000398	biological_process	mRNA splicing, via spliceosome
9	0003723	molecular_function	RNA binding
9	0005515	molecular_function	protein binding
9	0005634	cellular_component	nucleus
9	0005654	cellular_component	nucleoplasm
9	0005681	cellular_component	spliceosomal complex
9	0005684	cellular_component	U2-type spliceosomal complex
9	0005686	cellular_component	U2 snRNP
9	0006397	biological_process	mRNA processing
9	0016607	cellular_component	nuclear speck
9	0030515	molecular_function	snoRNA binding
9	0045292	biological_process	mRNA cis splicing, via spliceosome
9	0071005	cellular_component	U2-type precatalytic spliceosome
9	0071006	cellular_component	U2-type catalytic step 1 spliceosome
9	0071011	cellular_component	precatalytic spliceosome
9	0071013	cellular_component	catalytic step 2 spliceosome
9	1903241	biological_process	U2-type prespliceosome assembly
A6	0000380	biological_process	alternative mRNA splicing, via spliceosome
A6	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
A6	0000395	biological_process	mRNA 5'-splice site recognition
A6	0000398	biological_process	mRNA splicing, via spliceosome
A6	0000785	cellular_component	chromatin
A6	0003723	molecular_function	RNA binding
A6	0003729	molecular_function	mRNA binding
A6	0005515	molecular_function	protein binding
A6	0005634	cellular_component	nucleus
A6	0005654	cellular_component	nucleoplasm
A6	0005694	cellular_component	chromosome
A6	0005737	cellular_component	cytoplasm
A6	0005829	cellular_component	cytosol
A6	0006376	biological_process	mRNA splice site recognition
A6	0006397	biological_process	mRNA processing
A6	0016607	cellular_component	nuclear speck
A6	0033120	biological_process	positive regulation of RNA splicing
A6	0034504	biological_process	protein localization to nucleus
A6	0035145	cellular_component	exon-exon junction complex
A6	0043484	biological_process	regulation of RNA splicing
A6	0044547	molecular_function	DNA topoisomerase binding
A6	0046889	biological_process	positive regulation of lipid biosynthetic process
A6	0048255	biological_process	mRNA stabilization
A6	0050733	molecular_function	RS domain binding
A6	0071013	cellular_component	catalytic step 2 spliceosome
A6	0097398	biological_process	cellular response to interleukin-17
A6	0097400	biological_process	interleukin-17-mediated signaling pathway
A6	0110012	biological_process	protein localization to P-body
B	0000244	biological_process	spliceosomal tri-snRNP complex assembly
B	0000354	biological_process	cis assembly of pre-catalytic spliceosome
B	0000387	biological_process	spliceosomal snRNP assembly
B	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0001649	biological_process	osteoblast differentiation
B	0003723	molecular_function	RNA binding
B	0003724	molecular_function	RNA helicase activity
B	0004386	molecular_function	helicase activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005681	cellular_component	spliceosomal complex
B	0005682	cellular_component	U5 snRNP
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0030532	cellular_component	small nuclear ribonucleoprotein complex
B	0042802	molecular_function	identical protein binding
B	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
B	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
B	0071005	cellular_component	U2-type precatalytic spliceosome
B	0071006	cellular_component	U2-type catalytic step 1 spliceosome
B	0071007	cellular_component	U2-type catalytic step 2 spliceosome
B	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
B	0071011	cellular_component	precatalytic spliceosome
B	0071013	cellular_component	catalytic step 2 spliceosome
B	0071016	cellular_component	U12-type precatalytic spliceosome
B	0071018	cellular_component	U12-type catalytic step 2 spliceosome
B	0071020	cellular_component	post-spliceosomal complex
B1	0000245	biological_process	spliceosomal complex assembly
B1	0000375	biological_process	RNA splicing, via transesterification reactions
B1	0000387	biological_process	spliceosomal snRNP assembly
B1	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B1	0000398	biological_process	mRNA splicing, via spliceosome
B1	0003723	molecular_function	RNA binding
B1	0003729	molecular_function	mRNA binding
B1	0005515	molecular_function	protein binding
B1	0005634	cellular_component	nucleus
B1	0005654	cellular_component	nucleoplasm
B1	0005681	cellular_component	spliceosomal complex
B1	0005684	cellular_component	U2-type spliceosomal complex
B1	0005686	cellular_component	U2 snRNP
B1	0005689	cellular_component	U12-type spliceosomal complex
B1	0005730	cellular_component	nucleolus
B1	0006338	biological_process	chromatin remodeling
B1	0008380	biological_process	RNA splicing
B1	0016607	cellular_component	nuclear speck
B1	0031981	cellular_component	nuclear lumen
B1	0034693	cellular_component	U11/U12 snRNP
B1	0036002	molecular_function	pre-mRNA binding
B1	0045292	biological_process	mRNA cis splicing, via spliceosome
B1	0045943	biological_process	positive regulation of transcription by RNA polymerase I
B1	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B1	0045945	biological_process	positive regulation of transcription by RNA polymerase III
B1	0071004	cellular_component	U2-type prespliceosome
B1	0071005	cellular_component	U2-type precatalytic spliceosome
B1	0071006	cellular_component	U2-type catalytic step 1 spliceosome
B1	0071011	cellular_component	precatalytic spliceosome
B1	0071013	cellular_component	catalytic step 2 spliceosome
B1	0071016	cellular_component	U12-type precatalytic spliceosome
B1	0071018	cellular_component	U12-type catalytic step 2 spliceosome
B1	0110016	cellular_component	B-WICH complex
B1	1903241	biological_process	U2-type prespliceosome assembly
B1	1990935	molecular_function	splicing factor binding
B2	0000387	biological_process	spliceosomal snRNP assembly
B2	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B2	0000398	biological_process	mRNA splicing, via spliceosome
B2	0003723	molecular_function	RNA binding
B2	0005515	molecular_function	protein binding
B2	0005634	cellular_component	nucleus
B2	0005654	cellular_component	nucleoplasm
B2	0005681	cellular_component	spliceosomal complex
B2	0005684	cellular_component	U2-type spliceosomal complex
B2	0005686	cellular_component	U2 snRNP
B2	0005689	cellular_component	U12-type spliceosomal complex
B2	0006397	biological_process	mRNA processing
B2	0008380	biological_process	RNA splicing
B2	0016607	cellular_component	nuclear speck
B2	0034693	cellular_component	U11/U12 snRNP
B2	0071005	cellular_component	U2-type precatalytic spliceosome
B2	0071006	cellular_component	U2-type catalytic step 1 spliceosome
B2	0071011	cellular_component	precatalytic spliceosome
B2	0071013	cellular_component	catalytic step 2 spliceosome
B2	0071016	cellular_component	U12-type precatalytic spliceosome
B2	0071018	cellular_component	U12-type catalytic step 2 spliceosome
B2	1903241	biological_process	U2-type prespliceosome assembly
B3	0000124	cellular_component	SAGA complex
B3	0000375	biological_process	RNA splicing, via transesterification reactions
B3	0000387	biological_process	spliceosomal snRNP assembly
B3	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B3	0000398	biological_process	mRNA splicing, via spliceosome
B3	0005515	molecular_function	protein binding
B3	0005634	cellular_component	nucleus
B3	0005654	cellular_component	nucleoplasm
B3	0005681	cellular_component	spliceosomal complex
B3	0005684	cellular_component	U2-type spliceosomal complex
B3	0005686	cellular_component	U2 snRNP
B3	0005689	cellular_component	U12-type spliceosomal complex
B3	0005730	cellular_component	nucleolus
B3	0006282	biological_process	regulation of DNA repair
B3	0008380	biological_process	RNA splicing
B3	0030620	molecular_function	U2 snRNA binding
B3	0034693	cellular_component	U11/U12 snRNP
B3	0042177	biological_process	negative regulation of protein catabolic process
B3	0043484	biological_process	regulation of RNA splicing
B3	0044877	molecular_function	protein-containing complex binding
B3	0045893	biological_process	positive regulation of DNA-templated transcription
B3	0071005	cellular_component	U2-type precatalytic spliceosome
B3	0071006	cellular_component	U2-type catalytic step 1 spliceosome
B3	0071011	cellular_component	precatalytic spliceosome
B3	0071013	cellular_component	catalytic step 2 spliceosome
B3	0071016	cellular_component	U12-type precatalytic spliceosome
B3	0071018	cellular_component	U12-type catalytic step 2 spliceosome
B3	1903241	biological_process	U2-type prespliceosome assembly
B4	0000375	biological_process	RNA splicing, via transesterification reactions
B4	0000387	biological_process	spliceosomal snRNP assembly
B4	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B4	0000398	biological_process	mRNA splicing, via spliceosome
B4	0003723	molecular_function	RNA binding
B4	0005515	molecular_function	protein binding
B4	0005634	cellular_component	nucleus
B4	0005654	cellular_component	nucleoplasm
B4	0005681	cellular_component	spliceosomal complex
B4	0005684	cellular_component	U2-type spliceosomal complex
B4	0005686	cellular_component	U2 snRNP
B4	0005689	cellular_component	U12-type spliceosomal complex
B4	0006397	biological_process	mRNA processing
B4	0008380	biological_process	RNA splicing
B4	0034693	cellular_component	U11/U12 snRNP
B4	0071005	cellular_component	U2-type precatalytic spliceosome
B4	0071006	cellular_component	U2-type catalytic step 1 spliceosome
B4	0071011	cellular_component	precatalytic spliceosome
B4	0071016	cellular_component	U12-type precatalytic spliceosome
B4	0071018	cellular_component	U12-type catalytic step 2 spliceosome
B4	1903241	biological_process	U2-type prespliceosome assembly
B4	1990935	molecular_function	splicing factor binding
B5	0000124	cellular_component	SAGA complex
B5	0000387	biological_process	spliceosomal snRNP assembly
B5	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B5	0000398	biological_process	mRNA splicing, via spliceosome
B5	0003723	molecular_function	RNA binding
B5	0005515	molecular_function	protein binding
B5	0005634	cellular_component	nucleus
B5	0005654	cellular_component	nucleoplasm
B5	0005681	cellular_component	spliceosomal complex
B5	0005684	cellular_component	U2-type spliceosomal complex
B5	0005686	cellular_component	U2 snRNP
B5	0005689	cellular_component	U12-type spliceosomal complex
B5	0006282	biological_process	regulation of DNA repair
B5	0034693	cellular_component	U11/U12 snRNP
B5	0043484	biological_process	regulation of RNA splicing
B5	0045893	biological_process	positive regulation of DNA-templated transcription
B5	0071005	cellular_component	U2-type precatalytic spliceosome
B5	0071006	cellular_component	U2-type catalytic step 1 spliceosome
B5	0071011	cellular_component	precatalytic spliceosome
B5	0071016	cellular_component	U12-type precatalytic spliceosome
B5	0071018	cellular_component	U12-type catalytic step 2 spliceosome
B5	1903241	biological_process	U2-type prespliceosome assembly
B5	1990935	molecular_function	splicing factor binding
B6	0000387	biological_process	spliceosomal snRNP assembly
B6	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B6	0000398	biological_process	mRNA splicing, via spliceosome
B6	0003723	molecular_function	RNA binding
B6	0003729	molecular_function	mRNA binding
B6	0005515	molecular_function	protein binding
B6	0005634	cellular_component	nucleus
B6	0005654	cellular_component	nucleoplasm
B6	0005681	cellular_component	spliceosomal complex
B6	0005684	cellular_component	U2-type spliceosomal complex
B6	0005686	cellular_component	U2 snRNP
B6	0005689	cellular_component	U12-type spliceosomal complex
B6	0034693	cellular_component	U11/U12 snRNP
B6	0071006	cellular_component	U2-type catalytic step 1 spliceosome
B6	0071011	cellular_component	precatalytic spliceosome
B6	0071016	cellular_component	U12-type precatalytic spliceosome
B6	0071018	cellular_component	U12-type catalytic step 2 spliceosome
B6	1903241	biological_process	U2-type prespliceosome assembly
BL	0000398	biological_process	mRNA splicing, via spliceosome
BL	0000974	cellular_component	Prp19 complex
BL	0005515	molecular_function	protein binding
BL	0005634	cellular_component	nucleus
BL	0005654	cellular_component	nucleoplasm
BL	0005681	cellular_component	spliceosomal complex
BL	0005737	cellular_component	cytoplasm
BL	0010467	biological_process	gene expression
BL	0016020	cellular_component	membrane
BL	0016445	biological_process	somatic diversification of immunoglobulins
BL	0019899	molecular_function	enzyme binding
BL	0043065	biological_process	positive regulation of apoptotic process
C	0000244	biological_process	spliceosomal tri-snRNP complex assembly
C	0000387	biological_process	spliceosomal snRNP assembly
C	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003723	molecular_function	RNA binding
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005681	cellular_component	spliceosomal complex
C	0005682	cellular_component	U5 snRNP
C	0005829	cellular_component	cytosol
C	0015030	cellular_component	Cajal body
C	0016020	cellular_component	membrane
C	0016607	cellular_component	nuclear speck
C	0030623	molecular_function	U5 snRNA binding
C	0042220	biological_process	response to cocaine
C	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
C	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
C	0071005	cellular_component	U2-type precatalytic spliceosome
C	0071006	cellular_component	U2-type catalytic step 1 spliceosome
C	0071007	cellular_component	U2-type catalytic step 2 spliceosome
C	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
C	0071011	cellular_component	precatalytic spliceosome
C	0071013	cellular_component	catalytic step 2 spliceosome
C	0071014	cellular_component	post-mRNA release spliceosomal complex
C	0071016	cellular_component	U12-type precatalytic spliceosome
C	0071018	cellular_component	U12-type catalytic step 2 spliceosome
C	0071020	cellular_component	post-spliceosomal complex
C	0071466	biological_process	cellular response to xenobiotic stimulus
DH	0000398	biological_process	mRNA splicing, via spliceosome
DH	0003723	molecular_function	RNA binding
DH	0003724	molecular_function	RNA helicase activity
DH	0003725	molecular_function	double-stranded RNA binding
DH	0004386	molecular_function	helicase activity
DH	0005515	molecular_function	protein binding
DH	0005634	cellular_component	nucleus
DH	0005654	cellular_component	nucleoplasm
DH	0005681	cellular_component	spliceosomal complex
DH	0005689	cellular_component	U12-type spliceosomal complex
DH	0005730	cellular_component	nucleolus
DH	0006397	biological_process	mRNA processing
DH	0008186	molecular_function	ATP-dependent activity, acting on RNA
DH	0008380	biological_process	RNA splicing
DH	0009636	biological_process	response to toxic substance
DH	0016607	cellular_component	nuclear speck
DH	0016887	molecular_function	ATP hydrolysis activity
DH	0042742	biological_process	defense response to bacterium
DH	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
DH	0043279	biological_process	response to alkaloid
DH	0051607	biological_process	defense response to virus
DH	0071008	cellular_component	U2-type post-mRNA release spliceosomal complex
DH	0071014	cellular_component	post-mRNA release spliceosomal complex
DH	0140374	biological_process	antiviral innate immune response
E	0000244	biological_process	spliceosomal tri-snRNP complex assembly
E	0000375	biological_process	RNA splicing, via transesterification reactions
E	0000387	biological_process	spliceosomal snRNP assembly
E	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0003723	molecular_function	RNA binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005681	cellular_component	spliceosomal complex
E	0005682	cellular_component	U5 snRNP
E	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
E	0006396	biological_process	RNA processing
E	0008380	biological_process	RNA splicing
E	0016607	cellular_component	nuclear speck
E	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
E	0071006	cellular_component	U2-type catalytic step 1 spliceosome
E	0071007	cellular_component	U2-type catalytic step 2 spliceosome
E	0071009	cellular_component	U4atac/U6atac x U5 tri-snRNP complex
E	0071011	cellular_component	precatalytic spliceosome
E	0071013	cellular_component	catalytic step 2 spliceosome
E	0071014	cellular_component	post-mRNA release spliceosomal complex
E	0071016	cellular_component	U12-type precatalytic spliceosome
E	0071018	cellular_component	U12-type catalytic step 2 spliceosome
E	0071020	cellular_component	post-spliceosomal complex
G	0000398	biological_process	mRNA splicing, via spliceosome
G	0000974	cellular_component	Prp19 complex
G	0001650	cellular_component	fibrillar center
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005662	cellular_component	DNA replication factor A complex
G	0005681	cellular_component	spliceosomal complex
G	0016607	cellular_component	nuclear speck
G	0031965	cellular_component	nuclear membrane
G	0071006	cellular_component	U2-type catalytic step 1 spliceosome
G	0071007	cellular_component	U2-type catalytic step 2 spliceosome
G	0071013	cellular_component	catalytic step 2 spliceosome
G	0071014	cellular_component	post-mRNA release spliceosomal complex
G	0071018	cellular_component	U12-type catalytic step 2 spliceosome
G	0071020	cellular_component	post-spliceosomal complex
I	0000398	biological_process	mRNA splicing, via spliceosome
I	0003723	molecular_function	RNA binding
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0071005	cellular_component	U2-type precatalytic spliceosome
I	0071011	cellular_component	precatalytic spliceosome
K	0000398	biological_process	mRNA splicing, via spliceosome
K	0001527	cellular_component	microfibril
K	0003723	molecular_function	RNA binding
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005684	cellular_component	U2-type spliceosomal complex
K	0071005	cellular_component	U2-type precatalytic spliceosome
K	0140149	cellular_component	non-collagenous component of interstitial matrix
L	0000077	biological_process	DNA damage checkpoint signaling
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0000974	cellular_component	Prp19 complex
L	0000977	molecular_function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
L	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
L	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
L	0003677	molecular_function	DNA binding
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005662	cellular_component	DNA replication factor A complex
L	0005681	cellular_component	spliceosomal complex
L	0005737	cellular_component	cytoplasm
L	0006355	biological_process	regulation of DNA-templated transcription
L	0006357	biological_process	regulation of transcription by RNA polymerase II
L	0016020	cellular_component	membrane
L	0016607	cellular_component	nuclear speck
L	0019904	molecular_function	protein domain specific binding
L	0042802	molecular_function	identical protein binding
L	0045944	biological_process	positive regulation of transcription by RNA polymerase II
L	0071006	cellular_component	U2-type catalytic step 1 spliceosome
L	0071007	cellular_component	U2-type catalytic step 2 spliceosome
L	0071013	cellular_component	catalytic step 2 spliceosome
L	0071014	cellular_component	post-mRNA release spliceosomal complex
L	0071018	cellular_component	U12-type catalytic step 2 spliceosome
L	0071020	cellular_component	post-spliceosomal complex
L	0071987	molecular_function	WD40-repeat domain binding
P7	0000398	biological_process	mRNA splicing, via spliceosome
P7	0003723	molecular_function	RNA binding
P7	0005515	molecular_function	protein binding
P7	0005634	cellular_component	nucleus
P7	0005654	cellular_component	nucleoplasm
P7	0005681	cellular_component	spliceosomal complex
P7	0016607	cellular_component	nuclear speck
P7	0071006	cellular_component	U2-type catalytic step 1 spliceosome
P7	0071007	cellular_component	U2-type catalytic step 2 spliceosome
P7	0071013	cellular_component	catalytic step 2 spliceosome
P7	0071014	cellular_component	post-mRNA release spliceosomal complex
P7	0071020	cellular_component	post-spliceosomal complex
P7	1990403	biological_process	embryonic brain development
q	0000398	biological_process	mRNA splicing, via spliceosome
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005654	cellular_component	nucleoplasm
q	0005737	cellular_component	cytoplasm
q	0005829	cellular_component	cytosol
q	0015030	cellular_component	Cajal body
q	0031386	molecular_function	protein tag activity
q	1903749	biological_process	positive regulation of protein localization to mitochondrion
Q	0000398	biological_process	mRNA splicing, via spliceosome
Q	0000785	cellular_component	chromatin
Q	0003713	molecular_function	transcription coactivator activity
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005681	cellular_component	spliceosomal complex
Q	0016922	molecular_function	nuclear receptor binding
Q	0045893	biological_process	positive regulation of DNA-templated transcription
Q	0071006	cellular_component	U2-type catalytic step 1 spliceosome
Q	0071007	cellular_component	U2-type catalytic step 2 spliceosome
Q	0071014	cellular_component	post-mRNA release spliceosomal complex
Q	0071020	cellular_component	post-spliceosomal complex
r	0000398	biological_process	mRNA splicing, via spliceosome
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005654	cellular_component	nucleoplasm
r	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
r	0071005	cellular_component	U2-type precatalytic spliceosome
R	0000398	biological_process	mRNA splicing, via spliceosome
R	0000974	cellular_component	Prp19 complex
R	0003723	molecular_function	RNA binding
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005681	cellular_component	spliceosomal complex
R	0016607	cellular_component	nuclear speck
R	0045292	biological_process	mRNA cis splicing, via spliceosome
R	0071006	cellular_component	U2-type catalytic step 1 spliceosome
R	0071007	cellular_component	U2-type catalytic step 2 spliceosome
R	0071013	cellular_component	catalytic step 2 spliceosome
R	0071014	cellular_component	post-mRNA release spliceosomal complex
R	0071018	cellular_component	U12-type catalytic step 2 spliceosome
R	0071020	cellular_component	post-spliceosomal complex
S1	0000122	biological_process	negative regulation of transcription by RNA polymerase II
S1	0000398	biological_process	mRNA splicing, via spliceosome
S1	0003713	molecular_function	transcription coactivator activity
S1	0003714	molecular_function	transcription corepressor activity
S1	0003723	molecular_function	RNA binding
S1	0005112	molecular_function	Notch binding
S1	0005515	molecular_function	protein binding
S1	0005634	cellular_component	nucleus
S1	0005654	cellular_component	nucleoplasm
S1	0005681	cellular_component	spliceosomal complex
S1	0006357	biological_process	regulation of transcription by RNA polymerase II
S1	0008024	cellular_component	cyclin/CDK positive transcription elongation factor complex
S1	0016363	cellular_component	nuclear matrix
S1	0016607	cellular_component	nuclear speck
S1	0016922	molecular_function	nuclear receptor binding
S1	0019899	molecular_function	enzyme binding
S1	0030511	biological_process	positive regulation of transforming growth factor beta receptor signaling pathway
S1	0042771	biological_process	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
S1	0042809	molecular_function	nuclear vitamin D receptor binding
S1	0042974	molecular_function	nuclear retinoic acid receptor binding
S1	0043923	biological_process	host-mediated activation of viral transcription
S1	0045892	biological_process	negative regulation of DNA-templated transcription
S1	0045944	biological_process	positive regulation of transcription by RNA polymerase II
S1	0046332	molecular_function	SMAD binding
S1	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
S1	0048255	biological_process	mRNA stabilization
S1	0048384	biological_process	retinoic acid receptor signaling pathway
S1	0048385	biological_process	regulation of retinoic acid receptor signaling pathway
S1	0050681	molecular_function	nuclear androgen receptor binding
S1	0050769	biological_process	positive regulation of neurogenesis
S1	0070562	biological_process	regulation of vitamin D receptor signaling pathway
S1	0070564	biological_process	positive regulation of vitamin D receptor signaling pathway
S1	0071006	cellular_component	U2-type catalytic step 1 spliceosome
S1	0071007	cellular_component	U2-type catalytic step 2 spliceosome
S1	0071013	cellular_component	catalytic step 2 spliceosome
S1	0071014	cellular_component	post-mRNA release spliceosomal complex
S1	0071018	cellular_component	U12-type catalytic step 2 spliceosome
S1	0071020	cellular_component	post-spliceosomal complex
S1	0071300	biological_process	cellular response to retinoic acid
SR	0003723	molecular_function	RNA binding
SR	0005515	molecular_function	protein binding
SR	0005634	cellular_component	nucleus
SR	0005654	cellular_component	nucleoplasm
SR	0005686	cellular_component	U2 snRNP
t	0000209	biological_process	protein polyubiquitination
t	0000398	biological_process	mRNA splicing, via spliceosome
t	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
t	0005515	molecular_function	protein binding
t	0005634	cellular_component	nucleus
t	0005654	cellular_component	nucleoplasm
t	0005681	cellular_component	spliceosomal complex
t	0005737	cellular_component	cytoplasm
t	0005796	cellular_component	Golgi lumen
t	0005886	cellular_component	plasma membrane
t	0016567	biological_process	protein ubiquitination
t	0034450	molecular_function	ubiquitin-ubiquitin ligase activity
t	0061630	molecular_function	ubiquitin protein ligase activity
t	0071006	cellular_component	U2-type catalytic step 1 spliceosome
t	0071013	cellular_component	catalytic step 2 spliceosome
t	0071018	cellular_component	U12-type catalytic step 2 spliceosome
t	0072659	biological_process	protein localization to plasma membrane
T	0000122	biological_process	negative regulation of transcription by RNA polymerase II
T	0003711	molecular_function	transcription elongation factor activity
T	0003712	molecular_function	transcription coregulator activity
T	0003713	molecular_function	transcription coactivator activity
T	0003714	molecular_function	transcription corepressor activity
T	0003723	molecular_function	RNA binding
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0006397	biological_process	mRNA processing
T	0008380	biological_process	RNA splicing
T	0016607	cellular_component	nuclear speck
T	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
T	0034244	biological_process	negative regulation of transcription elongation by RNA polymerase II
T	0042802	molecular_function	identical protein binding
T	0044390	molecular_function	ubiquitin-like protein conjugating enzyme binding
T	0045944	biological_process	positive regulation of transcription by RNA polymerase II
T	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
T	0070063	molecular_function	RNA polymerase binding
v	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
v	0000398	biological_process	mRNA splicing, via spliceosome
v	0005515	molecular_function	protein binding
v	0005634	cellular_component	nucleus
v	0005654	cellular_component	nucleoplasm
v	0005737	cellular_component	cytoplasm
v	0008380	biological_process	RNA splicing
v	0016607	cellular_component	nuclear speck
v	0071005	cellular_component	U2-type precatalytic spliceosome
v	0071011	cellular_component	precatalytic spliceosome
w	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
w	0000398	biological_process	mRNA splicing, via spliceosome
w	0005515	molecular_function	protein binding
w	0005634	cellular_component	nucleus
w	0005654	cellular_component	nucleoplasm
w	0005737	cellular_component	cytoplasm
w	0008380	biological_process	RNA splicing
w	0016607	cellular_component	nuclear speck
w	0071005	cellular_component	U2-type precatalytic spliceosome
w	0071011	cellular_component	precatalytic spliceosome
x	0000228	cellular_component	nuclear chromosome
x	0000278	biological_process	mitotic cell cycle
x	0000398	biological_process	mRNA splicing, via spliceosome
x	0000922	cellular_component	spindle pole
x	0005515	molecular_function	protein binding
x	0005634	cellular_component	nucleus
x	0005654	cellular_component	nucleoplasm
x	0005694	cellular_component	chromosome
x	0007094	biological_process	mitotic spindle assembly checkpoint signaling
x	0016607	cellular_component	nuclear speck
x	0034501	biological_process	protein localization to kinetochore
x	0042802	molecular_function	identical protein binding
x	0071005	cellular_component	U2-type precatalytic spliceosome
x	0097431	cellular_component	mitotic spindle pole
X	0003697	molecular_function	single-stranded DNA binding
X	0003723	molecular_function	RNA binding
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0008380	biological_process	RNA splicing
X	0019888	molecular_function	protein phosphatase regulator activity
X	0050699	molecular_function	WW domain binding
y	0000228	cellular_component	nuclear chromosome
y	0000278	biological_process	mitotic cell cycle
y	0000398	biological_process	mRNA splicing, via spliceosome
y	0000922	cellular_component	spindle pole
y	0005515	molecular_function	protein binding
y	0005634	cellular_component	nucleus
y	0005654	cellular_component	nucleoplasm
y	0005694	cellular_component	chromosome
y	0007094	biological_process	mitotic spindle assembly checkpoint signaling
y	0016607	cellular_component	nuclear speck
y	0034501	biological_process	protein localization to kinetochore
y	0042802	molecular_function	identical protein binding
y	0071005	cellular_component	U2-type precatalytic spliceosome
y	0097431	cellular_component	mitotic spindle pole

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cnv..CdcvVkdsinfldHingkkH

Chain	Residue	Details
r	CYS82-HIS104

---

site_id	PS00170
Number of Residues	18
Details	CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YdgTiFHRSIrnFViQGG

Chain	Residue	Details
t	TYR316-GLY333

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LASAgfDrLILLWNV

Chain	Residue	Details
E	LEU81-VAL95
v	ILE364-MET378
E	LEU124-SER138
E	VAL167-ILE181
E	ILE208-LEU222
E	ILE300-THR314
G	LEU303-VAL317
G	ILE345-LEU359
P7	LEU304-VAL318
v	LEU229-PHE243

---

site_id	PS00690
Number of Residues	10
Details	DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. GvIILDEAHE

Chain	Residue	Details
DH	GLY255-GLU264

---

site_id	PS00997
Number of Residues	23
Details	G10_1 G10 protein signature 1. LCClRCiqtrDtNfgtnCiCRVP

Chain	Residue	Details
Q	LEU100-PRO122

---

site_id	PS00998
Number of Residues	10
Details	G10_2 G10 protein signature 2. CtHCGCRGCS

Chain	Residue	Details
Q	CYS134-SER143

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	183
Details	Domain: {"description":"Helicase ATP-binding 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	237
Details	Domain: {"description":"Helicase C-terminal 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	305
Details	Domain: {"description":"SEC63 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	175
Details	Domain: {"description":"Helicase ATP-binding 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	208
Details	Domain: {"description":"Helicase C-terminal 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	312
Details	Domain: {"description":"SEC63 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Motif: {"description":"DEIH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	3
Details	Motif: {"description":"DEVH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23045696","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4F93","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"F1LNJ2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	11
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q6P4T2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	17
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	42
Details	Repeat: {"description":"SURP motif 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	Site: {"description":"Critical for binding to SF3A3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	282
Details	Domain: {"description":"tr-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	14
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	78
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	78
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	79
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	78
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	79
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	77
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	32
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	3
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	178
Details	Region: {"description":"N-terminal protein interaction domain","evidences":[{"source":"PubMed","id":"26673105","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	8
Details	Region: {"description":"Interaction with AR","evidences":[{"source":"PubMed","id":"28076346","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	58
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	9
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	72
Details	Domain: {"description":"Ubiquitin-like"}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	24
Details	Zinc finger: {"description":"Matrin-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25772364","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	34
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	79
Details	Domain: {"description":"RRM 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	508
Details	Domain: {"description":"Sm","evidences":[{"source":"PROSITE-ProRule","id":"PRU01346","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	79
Details	Region: {"description":"Sufficient for interaction with CLNS1A","evidences":[{"source":"PubMed","id":"11747828","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	21
Details	Repeat: {"description":"LRR 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	21
Details	Repeat: {"description":"LRR 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	21
Details	Repeat: {"description":"LRR 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	21
Details	Repeat: {"description":"LRR 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	38
Details	Domain: {"description":"LRRCT"}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	61
Details	Zinc finger: {"description":"Matrin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00130","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	4
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"source":"PubMed","id":"21349847","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	40
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"OCT-2004","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	1
Details	Modified residue: {"description":"Symmetric dimethylarginine; by PRMT9; alternate","evidences":[{"source":"PubMed","id":"25737013","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	1
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	77
Details	Region: {"description":"Interaction with SF3B1 and SF3B3","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	7
Details	Site: {"description":"Interaction with RNA","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	37
Details	Region: {"description":"Interaction with PHF5A, SF3B1 and SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	56
Details	Region: {"description":"Interaction with SF3B1 and SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	21
Details	Region: {"description":"Interaction with SF3B1","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI57
Number of Residues	23
Details	Region: {"description":"Interaction with SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI58
Number of Residues	5
Details	Site: {"description":"Interaction with SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI59
Number of Residues	2
Details	Site: {"description":"Interaction with SF3B1","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI60
Number of Residues	39
Details	Repeat: {"description":"HEAT 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI61
Number of Residues	76
Details	Repeat: {"description":"HEAT 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI62
Number of Residues	37
Details	Repeat: {"description":"HEAT 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI63
Number of Residues	34
Details	Repeat: {"description":"HEAT 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI64
Number of Residues	38
Details	Repeat: {"description":"HEAT 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI65
Number of Residues	38
Details	Repeat: {"description":"HEAT 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI66
Number of Residues	38
Details	Repeat: {"description":"HEAT 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI67
Number of Residues	38
Details	Repeat: {"description":"HEAT 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI68
Number of Residues	38
Details	Repeat: {"description":"HEAT 9"}

Chain

Residue

Details

---

site_id	SWS_FT_FI69
Number of Residues	38
Details	Repeat: {"description":"HEAT 10"}

Chain

Residue

Details

---

site_id	SWS_FT_FI70
Number of Residues	38
Details	Repeat: {"description":"HEAT 11"}

Chain

Residue

Details

---

site_id	SWS_FT_FI71
Number of Residues	39
Details	Region: {"description":"Interaction with SF3B14"}

Chain

Residue

Details

---

site_id	SWS_FT_FI72
Number of Residues	4
Details	Region: {"description":"Interaction with PHF5A","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI73
Number of Residues	56
Details	Region: {"description":"Interaction with SF3B3 and SF3B5","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI74
Number of Residues	1
Details	Site: {"description":"Interaction with PHF5A","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI75
Number of Residues	4
Details	Site: {"description":"Interaction with SF3B3","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI76
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI77
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI78
Number of Residues	75
Details	Domain: {"description":"RRM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI79
Number of Residues	13
Details	Region: {"description":"Interaction with pre-mRNA branch site"}

Chain

Residue

Details

---

site_id	SWS_FT_FI80
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI81
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI82
Number of Residues	50
Details	Repeat: {"description":"ARM 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI83
Number of Residues	44
Details	Repeat: {"description":"ARM 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI84
Number of Residues	49
Details	Repeat: {"description":"ARM 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI85
Number of Residues	38
Details	Repeat: {"description":"ARM 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI86
Number of Residues	53
Details	Repeat: {"description":"ARM 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI87
Number of Residues	64
Details	Coiled coil: {"evidences":[{"source":"PubMed","id":"24269683","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI88
Number of Residues	10
Details	Motif: {"description":"Nuclear export signal (NES)","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI89
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI90
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI91
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI92
Number of Residues	166
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI93
Number of Residues	3
Details	Motif: {"description":"DEAH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI94
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI95
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI96
Number of Residues	64
Details	Domain: {"description":"LisH","evidences":[{"source":"PROSITE-ProRule","id":"PRU00126","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI97
Number of Residues	104
Details	Domain: {"description":"CTLH","evidences":[{"source":"PROSITE-ProRule","id":"PRU00058","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI98
Number of Residues	82
Details	Repeat: {"description":"WD 2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI99
Number of Residues	82
Details	Repeat: {"description":"WD 3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI100
Number of Residues	78
Details	Repeat: {"description":"WD 4","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI101
Number of Residues	82
Details	Repeat: {"description":"WD 5","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI102
Number of Residues	78
Details	Repeat: {"description":"WD 6","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI103
Number of Residues	62
Details	Repeat: {"description":"WD 7","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI104
Number of Residues	41
Details	Repeat: {"description":"WD 1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI105
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17525332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI106
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2007","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Matallanas D.","Cooper W.N.","Kolch W."]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI107
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25772364","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI108
Number of Residues	54
Details	Domain: {"description":"FF 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI109
Number of Residues	56
Details	Domain: {"description":"FF 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI110
Number of Residues	56
Details	Domain: {"description":"FF 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI111
Number of Residues	65
Details	Domain: {"description":"FF 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI112
Number of Residues	25
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI113
Number of Residues	3
Details	Region: {"description":"Interaction with SF3B3","evidences":[{"source":"PubMed","id":"27720643","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI114
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28541300","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IFE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5SYB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI115
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"UniProtKB","id":"P83870","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---