9PE1

Structure of beta-1,3-glucan synthase in complex with caspofungin, Rho1 and long glucan

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000148	cellular_component	1,3-beta-D-glucan synthase complex
A	0003843	molecular_function	1,3-beta-D-glucan synthase activity
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005886	cellular_component	plasma membrane
A	0005933	cellular_component	cellular bud
A	0005934	cellular_component	cellular bud tip
A	0005935	cellular_component	cellular bud neck
A	0006075	biological_process	(1->3)-beta-D-glucan biosynthetic process
A	0008361	biological_process	regulation of cell size
A	0009272	biological_process	fungal-type cell wall biogenesis
A	0009277	cellular_component	fungal-type cell wall
A	0030476	biological_process	ascospore wall assembly
A	0030479	cellular_component	actin cortical patch
A	0045807	biological_process	positive regulation of endocytosis
A	0051278	biological_process	fungal-type cell wall polysaccharide biosynthetic process
A	0071944	cellular_component	cell periphery
E	0000131	cellular_component	incipient cellular bud site
E	0000148	cellular_component	1,3-beta-D-glucan synthase complex
E	0000329	cellular_component	fungal-type vacuole membrane
E	0003924	molecular_function	GTPase activity
E	0003925	molecular_function	G protein activity
E	0005515	molecular_function	protein binding
E	0005525	molecular_function	GTP binding
E	0005739	cellular_component	mitochondrion
E	0005741	cellular_component	mitochondrial outer membrane
E	0005777	cellular_component	peroxisome
E	0005778	cellular_component	peroxisomal membrane
E	0005783	cellular_component	endoplasmic reticulum
E	0005794	cellular_component	Golgi apparatus
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0005933	cellular_component	cellular bud
E	0005934	cellular_component	cellular bud tip
E	0005935	cellular_component	cellular bud neck
E	0006075	biological_process	(1->3)-beta-D-glucan biosynthetic process
E	0007015	biological_process	actin filament organization
E	0007117	biological_process	budding cell bud growth
E	0007165	biological_process	signal transduction
E	0007264	biological_process	small GTPase-mediated signal transduction
E	0008047	molecular_function	enzyme activator activity
E	0008361	biological_process	regulation of cell size
E	0009272	biological_process	fungal-type cell wall biogenesis
E	0009277	cellular_component	fungal-type cell wall
E	0010008	cellular_component	endosome membrane
E	0016020	cellular_component	membrane
E	0019901	molecular_function	protein kinase binding
E	0030036	biological_process	actin cytoskeleton organization
E	0030476	biological_process	ascospore wall assembly
E	0031160	cellular_component	spore wall
E	0031681	molecular_function	G-protein beta-subunit binding
E	0032186	biological_process	cellular bud neck septin ring organization
E	0032880	biological_process	regulation of protein localization
E	0032889	biological_process	regulation of vacuole fusion, non-autophagic
E	0032956	biological_process	regulation of actin cytoskeleton organization
E	0043332	cellular_component	mating projection tip
E	0045807	biological_process	positive regulation of endocytosis
E	0060178	biological_process	regulation of exocyst localization
E	0060237	biological_process	regulation of fungal-type cell wall organization
E	0071944	cellular_component	cell periphery
E	0090334	biological_process	regulation of cell wall (1->3)-beta-D-glucan biosynthetic process
E	1903395	biological_process	regulation of secondary cell septum biogenesis
E	1903501	biological_process	positive regulation of mitotic actomyosin contractile ring assembly
G	0000148	cellular_component	1,3-beta-D-glucan synthase complex
G	0005933	cellular_component	cellular bud
G	0005934	cellular_component	cellular bud tip
G	0005935	cellular_component	cellular bud neck
G	0008047	molecular_function	enzyme activator activity
G	0043332	cellular_component	mating projection tip
G	0071944	cellular_component	cell periphery
G	0090334	biological_process	regulation of cell wall (1->3)-beta-D-glucan biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	282
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	214
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	46
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	Motif: {"description":"Effector region","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20062059","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3A58","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20062059","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3A58","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---