9O0Q

Crystal structure of GMPPNP-bound mutant MRAS in complex with MRTX1133

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Motif: {"description":"Effector region"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	57
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35831509","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7UPI","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35768504","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35830882","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35831509","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36175670","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SD0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TVF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7UPI","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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