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9NRN

Lipoprotein Lipase Helical Filament with 11 nm diameter

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0001523biological_processretinoid metabolic process
A0004465molecular_functionlipoprotein lipase activity
A0004620molecular_functionphospholipase activity
A0004806molecular_functiontriacylglycerol lipase activity
A0005102molecular_functionsignaling receptor binding
A0005509molecular_functioncalcium ion binding
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005886cellular_componentplasma membrane
A0006629biological_processlipid metabolic process
A0006631biological_processfatty acid metabolic process
A0006633biological_processfatty acid biosynthetic process
A0006641biological_processtriglyceride metabolic process
A0006644biological_processphospholipid metabolic process
A0008201molecular_functionheparin binding
A0008970molecular_functionphospholipase A1 activity
A0009749biological_processresponse to glucose
A0009986cellular_componentcell surface
A0010744biological_processpositive regulation of macrophage derived foam cell differentiation
A0010886biological_processpositive regulation of cholesterol storage
A0016042biological_processlipid catabolic process
A0016787molecular_functionhydrolase activity
A0019433biological_processtriglyceride catabolic process
A0031012cellular_componentextracellular matrix
A0031670biological_processcellular response to nutrient
A0032722biological_processpositive regulation of chemokine production
A0032731biological_processpositive regulation of interleukin-1 beta production
A0032755biological_processpositive regulation of interleukin-6 production
A0032760biological_processpositive regulation of tumor necrosis factor production
A0034185molecular_functionapolipoprotein binding
A0034361cellular_componentvery-low-density lipoprotein particle
A0034371biological_processchylomicron remodeling
A0034372biological_processvery-low-density lipoprotein particle remodeling
A0034375biological_processhigh-density lipoprotein particle remodeling
A0034447biological_processvery-low-density lipoprotein particle clearance
A0042627cellular_componentchylomicron
A0042632biological_processcholesterol homeostasis
A0042803molecular_functionprotein homodimerization activity
A0043395molecular_functionheparan sulfate proteoglycan binding
A0045600biological_processpositive regulation of fat cell differentiation
A0046872molecular_functionmetal ion binding
A0050729biological_processpositive regulation of inflammatory response
A0055096biological_processlow-density lipoprotein particle mediated signaling
A0070328biological_processtriglyceride homeostasis
A0071398biological_processcellular response to fatty acid
A0071813molecular_functionlipoprotein particle binding
A1904179biological_processpositive regulation of adipose tissue development
A2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
B0001523biological_processretinoid metabolic process
B0004465molecular_functionlipoprotein lipase activity
B0004620molecular_functionphospholipase activity
B0004806molecular_functiontriacylglycerol lipase activity
B0005102molecular_functionsignaling receptor binding
B0005509molecular_functioncalcium ion binding
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005886cellular_componentplasma membrane
B0006629biological_processlipid metabolic process
B0006631biological_processfatty acid metabolic process
B0006633biological_processfatty acid biosynthetic process
B0006641biological_processtriglyceride metabolic process
B0006644biological_processphospholipid metabolic process
B0008201molecular_functionheparin binding
B0008970molecular_functionphospholipase A1 activity
B0009749biological_processresponse to glucose
B0009986cellular_componentcell surface
B0010744biological_processpositive regulation of macrophage derived foam cell differentiation
B0010886biological_processpositive regulation of cholesterol storage
B0016042biological_processlipid catabolic process
B0016787molecular_functionhydrolase activity
B0019433biological_processtriglyceride catabolic process
B0031012cellular_componentextracellular matrix
B0031670biological_processcellular response to nutrient
B0032722biological_processpositive regulation of chemokine production
B0032731biological_processpositive regulation of interleukin-1 beta production
B0032755biological_processpositive regulation of interleukin-6 production
B0032760biological_processpositive regulation of tumor necrosis factor production
B0034185molecular_functionapolipoprotein binding
B0034361cellular_componentvery-low-density lipoprotein particle
B0034371biological_processchylomicron remodeling
B0034372biological_processvery-low-density lipoprotein particle remodeling
B0034375biological_processhigh-density lipoprotein particle remodeling
B0034447biological_processvery-low-density lipoprotein particle clearance
B0042627cellular_componentchylomicron
B0042632biological_processcholesterol homeostasis
B0042803molecular_functionprotein homodimerization activity
B0043395molecular_functionheparan sulfate proteoglycan binding
B0045600biological_processpositive regulation of fat cell differentiation
B0046872molecular_functionmetal ion binding
B0050729biological_processpositive regulation of inflammatory response
B0055096biological_processlow-density lipoprotein particle mediated signaling
B0070328biological_processtriglyceride homeostasis
B0071398biological_processcellular response to fatty acid
B0071813molecular_functionlipoprotein particle binding
B1904179biological_processpositive regulation of adipose tissue development
B2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
C0001523biological_processretinoid metabolic process
C0004465molecular_functionlipoprotein lipase activity
C0004620molecular_functionphospholipase activity
C0004806molecular_functiontriacylglycerol lipase activity
C0005102molecular_functionsignaling receptor binding
C0005509molecular_functioncalcium ion binding
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005886cellular_componentplasma membrane
C0006629biological_processlipid metabolic process
C0006631biological_processfatty acid metabolic process
C0006633biological_processfatty acid biosynthetic process
C0006641biological_processtriglyceride metabolic process
C0006644biological_processphospholipid metabolic process
C0008201molecular_functionheparin binding
C0008970molecular_functionphospholipase A1 activity
C0009749biological_processresponse to glucose
C0009986cellular_componentcell surface
C0010744biological_processpositive regulation of macrophage derived foam cell differentiation
C0010886biological_processpositive regulation of cholesterol storage
C0016042biological_processlipid catabolic process
C0016787molecular_functionhydrolase activity
C0019433biological_processtriglyceride catabolic process
C0031012cellular_componentextracellular matrix
C0031670biological_processcellular response to nutrient
C0032722biological_processpositive regulation of chemokine production
C0032731biological_processpositive regulation of interleukin-1 beta production
C0032755biological_processpositive regulation of interleukin-6 production
C0032760biological_processpositive regulation of tumor necrosis factor production
C0034185molecular_functionapolipoprotein binding
C0034361cellular_componentvery-low-density lipoprotein particle
C0034371biological_processchylomicron remodeling
C0034372biological_processvery-low-density lipoprotein particle remodeling
C0034375biological_processhigh-density lipoprotein particle remodeling
C0034447biological_processvery-low-density lipoprotein particle clearance
C0042627cellular_componentchylomicron
C0042632biological_processcholesterol homeostasis
C0042803molecular_functionprotein homodimerization activity
C0043395molecular_functionheparan sulfate proteoglycan binding
C0045600biological_processpositive regulation of fat cell differentiation
C0046872molecular_functionmetal ion binding
C0050729biological_processpositive regulation of inflammatory response
C0055096biological_processlow-density lipoprotein particle mediated signaling
C0070328biological_processtriglyceride homeostasis
C0071398biological_processcellular response to fatty acid
C0071813molecular_functionlipoprotein particle binding
C1904179biological_processpositive regulation of adipose tissue development
C2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
D0001523biological_processretinoid metabolic process
D0004465molecular_functionlipoprotein lipase activity
D0004620molecular_functionphospholipase activity
D0004806molecular_functiontriacylglycerol lipase activity
D0005102molecular_functionsignaling receptor binding
D0005509molecular_functioncalcium ion binding
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005886cellular_componentplasma membrane
D0006629biological_processlipid metabolic process
D0006631biological_processfatty acid metabolic process
D0006633biological_processfatty acid biosynthetic process
D0006641biological_processtriglyceride metabolic process
D0006644biological_processphospholipid metabolic process
D0008201molecular_functionheparin binding
D0008970molecular_functionphospholipase A1 activity
D0009749biological_processresponse to glucose
D0009986cellular_componentcell surface
D0010744biological_processpositive regulation of macrophage derived foam cell differentiation
D0010886biological_processpositive regulation of cholesterol storage
D0016042biological_processlipid catabolic process
D0016787molecular_functionhydrolase activity
D0019433biological_processtriglyceride catabolic process
D0031012cellular_componentextracellular matrix
D0031670biological_processcellular response to nutrient
D0032722biological_processpositive regulation of chemokine production
D0032731biological_processpositive regulation of interleukin-1 beta production
D0032755biological_processpositive regulation of interleukin-6 production
D0032760biological_processpositive regulation of tumor necrosis factor production
D0034185molecular_functionapolipoprotein binding
D0034361cellular_componentvery-low-density lipoprotein particle
D0034371biological_processchylomicron remodeling
D0034372biological_processvery-low-density lipoprotein particle remodeling
D0034375biological_processhigh-density lipoprotein particle remodeling
D0034447biological_processvery-low-density lipoprotein particle clearance
D0042627cellular_componentchylomicron
D0042632biological_processcholesterol homeostasis
D0042803molecular_functionprotein homodimerization activity
D0043395molecular_functionheparan sulfate proteoglycan binding
D0045600biological_processpositive regulation of fat cell differentiation
D0046872molecular_functionmetal ion binding
D0050729biological_processpositive regulation of inflammatory response
D0055096biological_processlow-density lipoprotein particle mediated signaling
D0070328biological_processtriglyceride homeostasis
D0071398biological_processcellular response to fatty acid
D0071813molecular_functionlipoprotein particle binding
D1904179biological_processpositive regulation of adipose tissue development
D2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
E0001523biological_processretinoid metabolic process
E0004465molecular_functionlipoprotein lipase activity
E0004620molecular_functionphospholipase activity
E0004806molecular_functiontriacylglycerol lipase activity
E0005102molecular_functionsignaling receptor binding
E0005509molecular_functioncalcium ion binding
E0005515molecular_functionprotein binding
E0005576cellular_componentextracellular region
E0005615cellular_componentextracellular space
E0005886cellular_componentplasma membrane
E0006629biological_processlipid metabolic process
E0006631biological_processfatty acid metabolic process
E0006633biological_processfatty acid biosynthetic process
E0006641biological_processtriglyceride metabolic process
E0006644biological_processphospholipid metabolic process
E0008201molecular_functionheparin binding
E0008970molecular_functionphospholipase A1 activity
E0009749biological_processresponse to glucose
E0009986cellular_componentcell surface
E0010744biological_processpositive regulation of macrophage derived foam cell differentiation
E0010886biological_processpositive regulation of cholesterol storage
E0016042biological_processlipid catabolic process
E0016787molecular_functionhydrolase activity
E0019433biological_processtriglyceride catabolic process
E0031012cellular_componentextracellular matrix
E0031670biological_processcellular response to nutrient
E0032722biological_processpositive regulation of chemokine production
E0032731biological_processpositive regulation of interleukin-1 beta production
E0032755biological_processpositive regulation of interleukin-6 production
E0032760biological_processpositive regulation of tumor necrosis factor production
E0034185molecular_functionapolipoprotein binding
E0034361cellular_componentvery-low-density lipoprotein particle
E0034371biological_processchylomicron remodeling
E0034372biological_processvery-low-density lipoprotein particle remodeling
E0034375biological_processhigh-density lipoprotein particle remodeling
E0034447biological_processvery-low-density lipoprotein particle clearance
E0042627cellular_componentchylomicron
E0042632biological_processcholesterol homeostasis
E0042803molecular_functionprotein homodimerization activity
E0043395molecular_functionheparan sulfate proteoglycan binding
E0045600biological_processpositive regulation of fat cell differentiation
E0046872molecular_functionmetal ion binding
E0050729biological_processpositive regulation of inflammatory response
E0055096biological_processlow-density lipoprotein particle mediated signaling
E0070328biological_processtriglyceride homeostasis
E0071398biological_processcellular response to fatty acid
E0071813molecular_functionlipoprotein particle binding
E1904179biological_processpositive regulation of adipose tissue development
E2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
F0001523biological_processretinoid metabolic process
F0004465molecular_functionlipoprotein lipase activity
F0004620molecular_functionphospholipase activity
F0004806molecular_functiontriacylglycerol lipase activity
F0005102molecular_functionsignaling receptor binding
F0005509molecular_functioncalcium ion binding
F0005515molecular_functionprotein binding
F0005576cellular_componentextracellular region
F0005615cellular_componentextracellular space
F0005886cellular_componentplasma membrane
F0006629biological_processlipid metabolic process
F0006631biological_processfatty acid metabolic process
F0006633biological_processfatty acid biosynthetic process
F0006641biological_processtriglyceride metabolic process
F0006644biological_processphospholipid metabolic process
F0008201molecular_functionheparin binding
F0008970molecular_functionphospholipase A1 activity
F0009749biological_processresponse to glucose
F0009986cellular_componentcell surface
F0010744biological_processpositive regulation of macrophage derived foam cell differentiation
F0010886biological_processpositive regulation of cholesterol storage
F0016042biological_processlipid catabolic process
F0016787molecular_functionhydrolase activity
F0019433biological_processtriglyceride catabolic process
F0031012cellular_componentextracellular matrix
F0031670biological_processcellular response to nutrient
F0032722biological_processpositive regulation of chemokine production
F0032731biological_processpositive regulation of interleukin-1 beta production
F0032755biological_processpositive regulation of interleukin-6 production
F0032760biological_processpositive regulation of tumor necrosis factor production
F0034185molecular_functionapolipoprotein binding
F0034361cellular_componentvery-low-density lipoprotein particle
F0034371biological_processchylomicron remodeling
F0034372biological_processvery-low-density lipoprotein particle remodeling
F0034375biological_processhigh-density lipoprotein particle remodeling
F0034447biological_processvery-low-density lipoprotein particle clearance
F0042627cellular_componentchylomicron
F0042632biological_processcholesterol homeostasis
F0042803molecular_functionprotein homodimerization activity
F0043395molecular_functionheparan sulfate proteoglycan binding
F0045600biological_processpositive regulation of fat cell differentiation
F0046872molecular_functionmetal ion binding
F0050729biological_processpositive regulation of inflammatory response
F0055096biological_processlow-density lipoprotein particle mediated signaling
F0070328biological_processtriglyceride homeostasis
F0071398biological_processcellular response to fatty acid
F0071813molecular_functionlipoprotein particle binding
F1904179biological_processpositive regulation of adipose tissue development
F2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
G0001523biological_processretinoid metabolic process
G0004465molecular_functionlipoprotein lipase activity
G0004620molecular_functionphospholipase activity
G0004806molecular_functiontriacylglycerol lipase activity
G0005102molecular_functionsignaling receptor binding
G0005509molecular_functioncalcium ion binding
G0005515molecular_functionprotein binding
G0005576cellular_componentextracellular region
G0005615cellular_componentextracellular space
G0005886cellular_componentplasma membrane
G0006629biological_processlipid metabolic process
G0006631biological_processfatty acid metabolic process
G0006633biological_processfatty acid biosynthetic process
G0006641biological_processtriglyceride metabolic process
G0006644biological_processphospholipid metabolic process
G0008201molecular_functionheparin binding
G0008970molecular_functionphospholipase A1 activity
G0009749biological_processresponse to glucose
G0009986cellular_componentcell surface
G0010744biological_processpositive regulation of macrophage derived foam cell differentiation
G0010886biological_processpositive regulation of cholesterol storage
G0016042biological_processlipid catabolic process
G0016787molecular_functionhydrolase activity
G0019433biological_processtriglyceride catabolic process
G0031012cellular_componentextracellular matrix
G0031670biological_processcellular response to nutrient
G0032722biological_processpositive regulation of chemokine production
G0032731biological_processpositive regulation of interleukin-1 beta production
G0032755biological_processpositive regulation of interleukin-6 production
G0032760biological_processpositive regulation of tumor necrosis factor production
G0034185molecular_functionapolipoprotein binding
G0034361cellular_componentvery-low-density lipoprotein particle
G0034371biological_processchylomicron remodeling
G0034372biological_processvery-low-density lipoprotein particle remodeling
G0034375biological_processhigh-density lipoprotein particle remodeling
G0034447biological_processvery-low-density lipoprotein particle clearance
G0042627cellular_componentchylomicron
G0042632biological_processcholesterol homeostasis
G0042803molecular_functionprotein homodimerization activity
G0043395molecular_functionheparan sulfate proteoglycan binding
G0045600biological_processpositive regulation of fat cell differentiation
G0046872molecular_functionmetal ion binding
G0050729biological_processpositive regulation of inflammatory response
G0055096biological_processlow-density lipoprotein particle mediated signaling
G0070328biological_processtriglyceride homeostasis
G0071398biological_processcellular response to fatty acid
G0071813molecular_functionlipoprotein particle binding
G1904179biological_processpositive regulation of adipose tissue development
G2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
H0001523biological_processretinoid metabolic process
H0004465molecular_functionlipoprotein lipase activity
H0004620molecular_functionphospholipase activity
H0004806molecular_functiontriacylglycerol lipase activity
H0005102molecular_functionsignaling receptor binding
H0005509molecular_functioncalcium ion binding
H0005515molecular_functionprotein binding
H0005576cellular_componentextracellular region
H0005615cellular_componentextracellular space
H0005886cellular_componentplasma membrane
H0006629biological_processlipid metabolic process
H0006631biological_processfatty acid metabolic process
H0006633biological_processfatty acid biosynthetic process
H0006641biological_processtriglyceride metabolic process
H0006644biological_processphospholipid metabolic process
H0008201molecular_functionheparin binding
H0008970molecular_functionphospholipase A1 activity
H0009749biological_processresponse to glucose
H0009986cellular_componentcell surface
H0010744biological_processpositive regulation of macrophage derived foam cell differentiation
H0010886biological_processpositive regulation of cholesterol storage
H0016042biological_processlipid catabolic process
H0016787molecular_functionhydrolase activity
H0019433biological_processtriglyceride catabolic process
H0031012cellular_componentextracellular matrix
H0031670biological_processcellular response to nutrient
H0032722biological_processpositive regulation of chemokine production
H0032731biological_processpositive regulation of interleukin-1 beta production
H0032755biological_processpositive regulation of interleukin-6 production
H0032760biological_processpositive regulation of tumor necrosis factor production
H0034185molecular_functionapolipoprotein binding
H0034361cellular_componentvery-low-density lipoprotein particle
H0034371biological_processchylomicron remodeling
H0034372biological_processvery-low-density lipoprotein particle remodeling
H0034375biological_processhigh-density lipoprotein particle remodeling
H0034447biological_processvery-low-density lipoprotein particle clearance
H0042627cellular_componentchylomicron
H0042632biological_processcholesterol homeostasis
H0042803molecular_functionprotein homodimerization activity
H0043395molecular_functionheparan sulfate proteoglycan binding
H0045600biological_processpositive regulation of fat cell differentiation
H0046872molecular_functionmetal ion binding
H0050729biological_processpositive regulation of inflammatory response
H0055096biological_processlow-density lipoprotein particle mediated signaling
H0070328biological_processtriglyceride homeostasis
H0071398biological_processcellular response to fatty acid
H0071813molecular_functionlipoprotein particle binding
H1904179biological_processpositive regulation of adipose tissue development
H2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
I0001523biological_processretinoid metabolic process
I0004465molecular_functionlipoprotein lipase activity
I0004620molecular_functionphospholipase activity
I0004806molecular_functiontriacylglycerol lipase activity
I0005102molecular_functionsignaling receptor binding
I0005509molecular_functioncalcium ion binding
I0005515molecular_functionprotein binding
I0005576cellular_componentextracellular region
I0005615cellular_componentextracellular space
I0005886cellular_componentplasma membrane
I0006629biological_processlipid metabolic process
I0006631biological_processfatty acid metabolic process
I0006633biological_processfatty acid biosynthetic process
I0006641biological_processtriglyceride metabolic process
I0006644biological_processphospholipid metabolic process
I0008201molecular_functionheparin binding
I0008970molecular_functionphospholipase A1 activity
I0009749biological_processresponse to glucose
I0009986cellular_componentcell surface
I0010744biological_processpositive regulation of macrophage derived foam cell differentiation
I0010886biological_processpositive regulation of cholesterol storage
I0016042biological_processlipid catabolic process
I0016787molecular_functionhydrolase activity
I0019433biological_processtriglyceride catabolic process
I0031012cellular_componentextracellular matrix
I0031670biological_processcellular response to nutrient
I0032722biological_processpositive regulation of chemokine production
I0032731biological_processpositive regulation of interleukin-1 beta production
I0032755biological_processpositive regulation of interleukin-6 production
I0032760biological_processpositive regulation of tumor necrosis factor production
I0034185molecular_functionapolipoprotein binding
I0034361cellular_componentvery-low-density lipoprotein particle
I0034371biological_processchylomicron remodeling
I0034372biological_processvery-low-density lipoprotein particle remodeling
I0034375biological_processhigh-density lipoprotein particle remodeling
I0034447biological_processvery-low-density lipoprotein particle clearance
I0042627cellular_componentchylomicron
I0042632biological_processcholesterol homeostasis
I0042803molecular_functionprotein homodimerization activity
I0043395molecular_functionheparan sulfate proteoglycan binding
I0045600biological_processpositive regulation of fat cell differentiation
I0046872molecular_functionmetal ion binding
I0050729biological_processpositive regulation of inflammatory response
I0055096biological_processlow-density lipoprotein particle mediated signaling
I0070328biological_processtriglyceride homeostasis
I0071398biological_processcellular response to fatty acid
I0071813molecular_functionlipoprotein particle binding
I1904179biological_processpositive regulation of adipose tissue development
I2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
J0001523biological_processretinoid metabolic process
J0004465molecular_functionlipoprotein lipase activity
J0004620molecular_functionphospholipase activity
J0004806molecular_functiontriacylglycerol lipase activity
J0005102molecular_functionsignaling receptor binding
J0005509molecular_functioncalcium ion binding
J0005515molecular_functionprotein binding
J0005576cellular_componentextracellular region
J0005615cellular_componentextracellular space
J0005886cellular_componentplasma membrane
J0006629biological_processlipid metabolic process
J0006631biological_processfatty acid metabolic process
J0006633biological_processfatty acid biosynthetic process
J0006641biological_processtriglyceride metabolic process
J0006644biological_processphospholipid metabolic process
J0008201molecular_functionheparin binding
J0008970molecular_functionphospholipase A1 activity
J0009749biological_processresponse to glucose
J0009986cellular_componentcell surface
J0010744biological_processpositive regulation of macrophage derived foam cell differentiation
J0010886biological_processpositive regulation of cholesterol storage
J0016042biological_processlipid catabolic process
J0016787molecular_functionhydrolase activity
J0019433biological_processtriglyceride catabolic process
J0031012cellular_componentextracellular matrix
J0031670biological_processcellular response to nutrient
J0032722biological_processpositive regulation of chemokine production
J0032731biological_processpositive regulation of interleukin-1 beta production
J0032755biological_processpositive regulation of interleukin-6 production
J0032760biological_processpositive regulation of tumor necrosis factor production
J0034185molecular_functionapolipoprotein binding
J0034361cellular_componentvery-low-density lipoprotein particle
J0034371biological_processchylomicron remodeling
J0034372biological_processvery-low-density lipoprotein particle remodeling
J0034375biological_processhigh-density lipoprotein particle remodeling
J0034447biological_processvery-low-density lipoprotein particle clearance
J0042627cellular_componentchylomicron
J0042632biological_processcholesterol homeostasis
J0042803molecular_functionprotein homodimerization activity
J0043395molecular_functionheparan sulfate proteoglycan binding
J0045600biological_processpositive regulation of fat cell differentiation
J0046872molecular_functionmetal ion binding
J0050729biological_processpositive regulation of inflammatory response
J0055096biological_processlow-density lipoprotein particle mediated signaling
J0070328biological_processtriglyceride homeostasis
J0071398biological_processcellular response to fatty acid
J0071813molecular_functionlipoprotein particle binding
J1904179biological_processpositive regulation of adipose tissue development
J2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
K0001523biological_processretinoid metabolic process
K0004465molecular_functionlipoprotein lipase activity
K0004620molecular_functionphospholipase activity
K0004806molecular_functiontriacylglycerol lipase activity
K0005102molecular_functionsignaling receptor binding
K0005509molecular_functioncalcium ion binding
K0005515molecular_functionprotein binding
K0005576cellular_componentextracellular region
K0005615cellular_componentextracellular space
K0005886cellular_componentplasma membrane
K0006629biological_processlipid metabolic process
K0006631biological_processfatty acid metabolic process
K0006633biological_processfatty acid biosynthetic process
K0006641biological_processtriglyceride metabolic process
K0006644biological_processphospholipid metabolic process
K0008201molecular_functionheparin binding
K0008970molecular_functionphospholipase A1 activity
K0009749biological_processresponse to glucose
K0009986cellular_componentcell surface
K0010744biological_processpositive regulation of macrophage derived foam cell differentiation
K0010886biological_processpositive regulation of cholesterol storage
K0016042biological_processlipid catabolic process
K0016787molecular_functionhydrolase activity
K0019433biological_processtriglyceride catabolic process
K0031012cellular_componentextracellular matrix
K0031670biological_processcellular response to nutrient
K0032722biological_processpositive regulation of chemokine production
K0032731biological_processpositive regulation of interleukin-1 beta production
K0032755biological_processpositive regulation of interleukin-6 production
K0032760biological_processpositive regulation of tumor necrosis factor production
K0034185molecular_functionapolipoprotein binding
K0034361cellular_componentvery-low-density lipoprotein particle
K0034371biological_processchylomicron remodeling
K0034372biological_processvery-low-density lipoprotein particle remodeling
K0034375biological_processhigh-density lipoprotein particle remodeling
K0034447biological_processvery-low-density lipoprotein particle clearance
K0042627cellular_componentchylomicron
K0042632biological_processcholesterol homeostasis
K0042803molecular_functionprotein homodimerization activity
K0043395molecular_functionheparan sulfate proteoglycan binding
K0045600biological_processpositive regulation of fat cell differentiation
K0046872molecular_functionmetal ion binding
K0050729biological_processpositive regulation of inflammatory response
K0055096biological_processlow-density lipoprotein particle mediated signaling
K0070328biological_processtriglyceride homeostasis
K0071398biological_processcellular response to fatty acid
K0071813molecular_functionlipoprotein particle binding
K1904179biological_processpositive regulation of adipose tissue development
K2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
L0001523biological_processretinoid metabolic process
L0004465molecular_functionlipoprotein lipase activity
L0004620molecular_functionphospholipase activity
L0004806molecular_functiontriacylglycerol lipase activity
L0005102molecular_functionsignaling receptor binding
L0005509molecular_functioncalcium ion binding
L0005515molecular_functionprotein binding
L0005576cellular_componentextracellular region
L0005615cellular_componentextracellular space
L0005886cellular_componentplasma membrane
L0006629biological_processlipid metabolic process
L0006631biological_processfatty acid metabolic process
L0006633biological_processfatty acid biosynthetic process
L0006641biological_processtriglyceride metabolic process
L0006644biological_processphospholipid metabolic process
L0008201molecular_functionheparin binding
L0008970molecular_functionphospholipase A1 activity
L0009749biological_processresponse to glucose
L0009986cellular_componentcell surface
L0010744biological_processpositive regulation of macrophage derived foam cell differentiation
L0010886biological_processpositive regulation of cholesterol storage
L0016042biological_processlipid catabolic process
L0016787molecular_functionhydrolase activity
L0019433biological_processtriglyceride catabolic process
L0031012cellular_componentextracellular matrix
L0031670biological_processcellular response to nutrient
L0032722biological_processpositive regulation of chemokine production
L0032731biological_processpositive regulation of interleukin-1 beta production
L0032755biological_processpositive regulation of interleukin-6 production
L0032760biological_processpositive regulation of tumor necrosis factor production
L0034185molecular_functionapolipoprotein binding
L0034361cellular_componentvery-low-density lipoprotein particle
L0034371biological_processchylomicron remodeling
L0034372biological_processvery-low-density lipoprotein particle remodeling
L0034375biological_processhigh-density lipoprotein particle remodeling
L0034447biological_processvery-low-density lipoprotein particle clearance
L0042627cellular_componentchylomicron
L0042632biological_processcholesterol homeostasis
L0042803molecular_functionprotein homodimerization activity
L0043395molecular_functionheparan sulfate proteoglycan binding
L0045600biological_processpositive regulation of fat cell differentiation
L0046872molecular_functionmetal ion binding
L0050729biological_processpositive regulation of inflammatory response
L0055096biological_processlow-density lipoprotein particle mediated signaling
L0070328biological_processtriglyceride homeostasis
L0071398biological_processcellular response to fatty acid
L0071813molecular_functionlipoprotein particle binding
L1904179biological_processpositive regulation of adipose tissue development
L2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
M0001523biological_processretinoid metabolic process
M0004465molecular_functionlipoprotein lipase activity
M0004620molecular_functionphospholipase activity
M0004806molecular_functiontriacylglycerol lipase activity
M0005102molecular_functionsignaling receptor binding
M0005509molecular_functioncalcium ion binding
M0005515molecular_functionprotein binding
M0005576cellular_componentextracellular region
M0005615cellular_componentextracellular space
M0005886cellular_componentplasma membrane
M0006629biological_processlipid metabolic process
M0006631biological_processfatty acid metabolic process
M0006633biological_processfatty acid biosynthetic process
M0006641biological_processtriglyceride metabolic process
M0006644biological_processphospholipid metabolic process
M0008201molecular_functionheparin binding
M0008970molecular_functionphospholipase A1 activity
M0009749biological_processresponse to glucose
M0009986cellular_componentcell surface
M0010744biological_processpositive regulation of macrophage derived foam cell differentiation
M0010886biological_processpositive regulation of cholesterol storage
M0016042biological_processlipid catabolic process
M0016787molecular_functionhydrolase activity
M0019433biological_processtriglyceride catabolic process
M0031012cellular_componentextracellular matrix
M0031670biological_processcellular response to nutrient
M0032722biological_processpositive regulation of chemokine production
M0032731biological_processpositive regulation of interleukin-1 beta production
M0032755biological_processpositive regulation of interleukin-6 production
M0032760biological_processpositive regulation of tumor necrosis factor production
M0034185molecular_functionapolipoprotein binding
M0034361cellular_componentvery-low-density lipoprotein particle
M0034371biological_processchylomicron remodeling
M0034372biological_processvery-low-density lipoprotein particle remodeling
M0034375biological_processhigh-density lipoprotein particle remodeling
M0034447biological_processvery-low-density lipoprotein particle clearance
M0042627cellular_componentchylomicron
M0042632biological_processcholesterol homeostasis
M0042803molecular_functionprotein homodimerization activity
M0043395molecular_functionheparan sulfate proteoglycan binding
M0045600biological_processpositive regulation of fat cell differentiation
M0046872molecular_functionmetal ion binding
M0050729biological_processpositive regulation of inflammatory response
M0055096biological_processlow-density lipoprotein particle mediated signaling
M0070328biological_processtriglyceride homeostasis
M0071398biological_processcellular response to fatty acid
M0071813molecular_functionlipoprotein particle binding
M1904179biological_processpositive regulation of adipose tissue development
M2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
N0001523biological_processretinoid metabolic process
N0004465molecular_functionlipoprotein lipase activity
N0004620molecular_functionphospholipase activity
N0004806molecular_functiontriacylglycerol lipase activity
N0005102molecular_functionsignaling receptor binding
N0005509molecular_functioncalcium ion binding
N0005515molecular_functionprotein binding
N0005576cellular_componentextracellular region
N0005615cellular_componentextracellular space
N0005886cellular_componentplasma membrane
N0006629biological_processlipid metabolic process
N0006631biological_processfatty acid metabolic process
N0006633biological_processfatty acid biosynthetic process
N0006641biological_processtriglyceride metabolic process
N0006644biological_processphospholipid metabolic process
N0008201molecular_functionheparin binding
N0008970molecular_functionphospholipase A1 activity
N0009749biological_processresponse to glucose
N0009986cellular_componentcell surface
N0010744biological_processpositive regulation of macrophage derived foam cell differentiation
N0010886biological_processpositive regulation of cholesterol storage
N0016042biological_processlipid catabolic process
N0016787molecular_functionhydrolase activity
N0019433biological_processtriglyceride catabolic process
N0031012cellular_componentextracellular matrix
N0031670biological_processcellular response to nutrient
N0032722biological_processpositive regulation of chemokine production
N0032731biological_processpositive regulation of interleukin-1 beta production
N0032755biological_processpositive regulation of interleukin-6 production
N0032760biological_processpositive regulation of tumor necrosis factor production
N0034185molecular_functionapolipoprotein binding
N0034361cellular_componentvery-low-density lipoprotein particle
N0034371biological_processchylomicron remodeling
N0034372biological_processvery-low-density lipoprotein particle remodeling
N0034375biological_processhigh-density lipoprotein particle remodeling
N0034447biological_processvery-low-density lipoprotein particle clearance
N0042627cellular_componentchylomicron
N0042632biological_processcholesterol homeostasis
N0042803molecular_functionprotein homodimerization activity
N0043395molecular_functionheparan sulfate proteoglycan binding
N0045600biological_processpositive regulation of fat cell differentiation
N0046872molecular_functionmetal ion binding
N0050729biological_processpositive regulation of inflammatory response
N0055096biological_processlow-density lipoprotein particle mediated signaling
N0070328biological_processtriglyceride homeostasis
N0071398biological_processcellular response to fatty acid
N0071813molecular_functionlipoprotein particle binding
N1904179biological_processpositive regulation of adipose tissue development
N2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
O0001523biological_processretinoid metabolic process
O0004465molecular_functionlipoprotein lipase activity
O0004620molecular_functionphospholipase activity
O0004806molecular_functiontriacylglycerol lipase activity
O0005102molecular_functionsignaling receptor binding
O0005509molecular_functioncalcium ion binding
O0005515molecular_functionprotein binding
O0005576cellular_componentextracellular region
O0005615cellular_componentextracellular space
O0005886cellular_componentplasma membrane
O0006629biological_processlipid metabolic process
O0006631biological_processfatty acid metabolic process
O0006633biological_processfatty acid biosynthetic process
O0006641biological_processtriglyceride metabolic process
O0006644biological_processphospholipid metabolic process
O0008201molecular_functionheparin binding
O0008970molecular_functionphospholipase A1 activity
O0009749biological_processresponse to glucose
O0009986cellular_componentcell surface
O0010744biological_processpositive regulation of macrophage derived foam cell differentiation
O0010886biological_processpositive regulation of cholesterol storage
O0016042biological_processlipid catabolic process
O0016787molecular_functionhydrolase activity
O0019433biological_processtriglyceride catabolic process
O0031012cellular_componentextracellular matrix
O0031670biological_processcellular response to nutrient
O0032722biological_processpositive regulation of chemokine production
O0032731biological_processpositive regulation of interleukin-1 beta production
O0032755biological_processpositive regulation of interleukin-6 production
O0032760biological_processpositive regulation of tumor necrosis factor production
O0034185molecular_functionapolipoprotein binding
O0034361cellular_componentvery-low-density lipoprotein particle
O0034371biological_processchylomicron remodeling
O0034372biological_processvery-low-density lipoprotein particle remodeling
O0034375biological_processhigh-density lipoprotein particle remodeling
O0034447biological_processvery-low-density lipoprotein particle clearance
O0042627cellular_componentchylomicron
O0042632biological_processcholesterol homeostasis
O0042803molecular_functionprotein homodimerization activity
O0043395molecular_functionheparan sulfate proteoglycan binding
O0045600biological_processpositive regulation of fat cell differentiation
O0046872molecular_functionmetal ion binding
O0050729biological_processpositive regulation of inflammatory response
O0055096biological_processlow-density lipoprotein particle mediated signaling
O0070328biological_processtriglyceride homeostasis
O0071398biological_processcellular response to fatty acid
O0071813molecular_functionlipoprotein particle binding
O1904179biological_processpositive regulation of adipose tissue development
O2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
P0001523biological_processretinoid metabolic process
P0004465molecular_functionlipoprotein lipase activity
P0004620molecular_functionphospholipase activity
P0004806molecular_functiontriacylglycerol lipase activity
P0005102molecular_functionsignaling receptor binding
P0005509molecular_functioncalcium ion binding
P0005515molecular_functionprotein binding
P0005576cellular_componentextracellular region
P0005615cellular_componentextracellular space
P0005886cellular_componentplasma membrane
P0006629biological_processlipid metabolic process
P0006631biological_processfatty acid metabolic process
P0006633biological_processfatty acid biosynthetic process
P0006641biological_processtriglyceride metabolic process
P0006644biological_processphospholipid metabolic process
P0008201molecular_functionheparin binding
P0008970molecular_functionphospholipase A1 activity
P0009749biological_processresponse to glucose
P0009986cellular_componentcell surface
P0010744biological_processpositive regulation of macrophage derived foam cell differentiation
P0010886biological_processpositive regulation of cholesterol storage
P0016042biological_processlipid catabolic process
P0016787molecular_functionhydrolase activity
P0019433biological_processtriglyceride catabolic process
P0031012cellular_componentextracellular matrix
P0031670biological_processcellular response to nutrient
P0032722biological_processpositive regulation of chemokine production
P0032731biological_processpositive regulation of interleukin-1 beta production
P0032755biological_processpositive regulation of interleukin-6 production
P0032760biological_processpositive regulation of tumor necrosis factor production
P0034185molecular_functionapolipoprotein binding
P0034361cellular_componentvery-low-density lipoprotein particle
P0034371biological_processchylomicron remodeling
P0034372biological_processvery-low-density lipoprotein particle remodeling
P0034375biological_processhigh-density lipoprotein particle remodeling
P0034447biological_processvery-low-density lipoprotein particle clearance
P0042627cellular_componentchylomicron
P0042632biological_processcholesterol homeostasis
P0042803molecular_functionprotein homodimerization activity
P0043395molecular_functionheparan sulfate proteoglycan binding
P0045600biological_processpositive regulation of fat cell differentiation
P0046872molecular_functionmetal ion binding
P0050729biological_processpositive regulation of inflammatory response
P0055096biological_processlow-density lipoprotein particle mediated signaling
P0070328biological_processtriglyceride homeostasis
P0071398biological_processcellular response to fatty acid
P0071813molecular_functionlipoprotein particle binding
P1904179biological_processpositive regulation of adipose tissue development
P2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
Q0001523biological_processretinoid metabolic process
Q0004465molecular_functionlipoprotein lipase activity
Q0004620molecular_functionphospholipase activity
Q0004806molecular_functiontriacylglycerol lipase activity
Q0005102molecular_functionsignaling receptor binding
Q0005509molecular_functioncalcium ion binding
Q0005515molecular_functionprotein binding
Q0005576cellular_componentextracellular region
Q0005615cellular_componentextracellular space
Q0005886cellular_componentplasma membrane
Q0006629biological_processlipid metabolic process
Q0006631biological_processfatty acid metabolic process
Q0006633biological_processfatty acid biosynthetic process
Q0006641biological_processtriglyceride metabolic process
Q0006644biological_processphospholipid metabolic process
Q0008201molecular_functionheparin binding
Q0008970molecular_functionphospholipase A1 activity
Q0009749biological_processresponse to glucose
Q0009986cellular_componentcell surface
Q0010744biological_processpositive regulation of macrophage derived foam cell differentiation
Q0010886biological_processpositive regulation of cholesterol storage
Q0016042biological_processlipid catabolic process
Q0016787molecular_functionhydrolase activity
Q0019433biological_processtriglyceride catabolic process
Q0031012cellular_componentextracellular matrix
Q0031670biological_processcellular response to nutrient
Q0032722biological_processpositive regulation of chemokine production
Q0032731biological_processpositive regulation of interleukin-1 beta production
Q0032755biological_processpositive regulation of interleukin-6 production
Q0032760biological_processpositive regulation of tumor necrosis factor production
Q0034185molecular_functionapolipoprotein binding
Q0034361cellular_componentvery-low-density lipoprotein particle
Q0034371biological_processchylomicron remodeling
Q0034372biological_processvery-low-density lipoprotein particle remodeling
Q0034375biological_processhigh-density lipoprotein particle remodeling
Q0034447biological_processvery-low-density lipoprotein particle clearance
Q0042627cellular_componentchylomicron
Q0042632biological_processcholesterol homeostasis
Q0042803molecular_functionprotein homodimerization activity
Q0043395molecular_functionheparan sulfate proteoglycan binding
Q0045600biological_processpositive regulation of fat cell differentiation
Q0046872molecular_functionmetal ion binding
Q0050729biological_processpositive regulation of inflammatory response
Q0055096biological_processlow-density lipoprotein particle mediated signaling
Q0070328biological_processtriglyceride homeostasis
Q0071398biological_processcellular response to fatty acid
Q0071813molecular_functionlipoprotein particle binding
Q1904179biological_processpositive regulation of adipose tissue development
Q2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
R0001523biological_processretinoid metabolic process
R0004465molecular_functionlipoprotein lipase activity
R0004620molecular_functionphospholipase activity
R0004806molecular_functiontriacylglycerol lipase activity
R0005102molecular_functionsignaling receptor binding
R0005509molecular_functioncalcium ion binding
R0005515molecular_functionprotein binding
R0005576cellular_componentextracellular region
R0005615cellular_componentextracellular space
R0005886cellular_componentplasma membrane
R0006629biological_processlipid metabolic process
R0006631biological_processfatty acid metabolic process
R0006633biological_processfatty acid biosynthetic process
R0006641biological_processtriglyceride metabolic process
R0006644biological_processphospholipid metabolic process
R0008201molecular_functionheparin binding
R0008970molecular_functionphospholipase A1 activity
R0009749biological_processresponse to glucose
R0009986cellular_componentcell surface
R0010744biological_processpositive regulation of macrophage derived foam cell differentiation
R0010886biological_processpositive regulation of cholesterol storage
R0016042biological_processlipid catabolic process
R0016787molecular_functionhydrolase activity
R0019433biological_processtriglyceride catabolic process
R0031012cellular_componentextracellular matrix
R0031670biological_processcellular response to nutrient
R0032722biological_processpositive regulation of chemokine production
R0032731biological_processpositive regulation of interleukin-1 beta production
R0032755biological_processpositive regulation of interleukin-6 production
R0032760biological_processpositive regulation of tumor necrosis factor production
R0034185molecular_functionapolipoprotein binding
R0034361cellular_componentvery-low-density lipoprotein particle
R0034371biological_processchylomicron remodeling
R0034372biological_processvery-low-density lipoprotein particle remodeling
R0034375biological_processhigh-density lipoprotein particle remodeling
R0034447biological_processvery-low-density lipoprotein particle clearance
R0042627cellular_componentchylomicron
R0042632biological_processcholesterol homeostasis
R0042803molecular_functionprotein homodimerization activity
R0043395molecular_functionheparan sulfate proteoglycan binding
R0045600biological_processpositive regulation of fat cell differentiation
R0046872molecular_functionmetal ion binding
R0050729biological_processpositive regulation of inflammatory response
R0055096biological_processlow-density lipoprotein particle mediated signaling
R0070328biological_processtriglyceride homeostasis
R0071398biological_processcellular response to fatty acid
R0071813molecular_functionlipoprotein particle binding
R1904179biological_processpositive regulation of adipose tissue development
R2000343biological_processpositive regulation of chemokine (C-X-C motif) ligand 2 production
Functional Information from PROSITE/UniProt
site_idPS00120
Number of Residues10
DetailsLIPASE_SER Lipases, serine active site. VHLLGYSLGA
ChainResidueDetails
AVAL156-ALA165

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2214
DetailsDomain: {"description":"PLAT","evidences":[{"source":"PROSITE-ProRule","id":"PRU00152","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues414
DetailsRegion: {"description":"Essential for determining substrate specificity","evidences":[{"source":"UniProtKB","id":"P06858","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues72
DetailsRegion: {"description":"Important for interaction with lipoprotein particles","evidences":[{"source":"UniProtKB","id":"P06858","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues72
DetailsRegion: {"description":"Important for heparin binding","evidences":[{"source":"UniProtKB","id":"P06858","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues18
DetailsActive site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"P06858","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues36
DetailsActive site: {"description":"Charge relay system","evidences":[{"source":"PROSITE-ProRule","id":"PRU10037","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues72
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"P06858","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI8
Number of Residues54
DetailsModified residue: {"description":"3'-nitrotyrosine","evidences":[{"source":"UniProtKB","id":"Q06000","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI9
Number of Residues36
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"2674142","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI10
Number of Residues18
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246905

PDB entries from 2025-12-31

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