Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9NPY

SARS-CoV-2 nsp1 bound to the Rhinolophus lepidus 40S ribosome (local refinement of the 40S head)

Functional Information from GO Data

Chain	GOid	namespace	contents
b	0003735	molecular_function	structural constituent of ribosome
b	0005737	cellular_component	cytoplasm
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
B	0003723	molecular_function	RNA binding
B	0003735	molecular_function	structural constituent of ribosome
B	0005634	cellular_component	nucleus
B	0005730	cellular_component	nucleolus
B	0005743	cellular_component	mitochondrial inner membrane
B	0005819	cellular_component	spindle
B	0006412	biological_process	translation
B	0015935	cellular_component	small ribosomal subunit
B	0022626	cellular_component	cytosolic ribosome
B	0022627	cellular_component	cytosolic small ribosomal subunit
B	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B	2001235	biological_process	positive regulation of apoptotic signaling pathway
c	0000028	biological_process	ribosomal small subunit assembly
c	0003735	molecular_function	structural constituent of ribosome
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0022626	cellular_component	cytosolic ribosome
c	0022627	cellular_component	cytosolic small ribosomal subunit
c	0030490	biological_process	maturation of SSU-rRNA
d	0002181	biological_process	cytoplasmic translation
d	0003735	molecular_function	structural constituent of ribosome
d	0005791	cellular_component	rough endoplasmic reticulum
d	0005829	cellular_component	cytosol
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
d	0008270	molecular_function	zinc ion binding
d	0022626	cellular_component	cytosolic ribosome
d	0022627	cellular_component	cytosolic small ribosomal subunit
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0006412	biological_process	translation
E	0015935	cellular_component	small ribosomal subunit
g	0006417	biological_process	regulation of translation
g	0030425	cellular_component	dendrite
g	0043022	molecular_function	ribosome binding
g	0045182	molecular_function	translation regulator activity
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005730	cellular_component	nucleolus
J	0005737	cellular_component	cytoplasm
J	0022626	cellular_component	cytosolic ribosome
J	0022627	cellular_component	cytosolic small ribosomal subunit
L	0003735	molecular_function	structural constituent of ribosome
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
O	0000028	biological_process	ribosomal small subunit assembly
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0015935	cellular_component	small ribosomal subunit
O	0022626	cellular_component	cytosolic ribosome
O	0022627	cellular_component	cytosolic small ribosomal subunit
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
R	0003735	molecular_function	structural constituent of ribosome
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
S	0003676	molecular_function	nucleic acid binding
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
T	0000028	biological_process	ribosomal small subunit assembly
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005634	cellular_component	nucleus
T	0005737	cellular_component	cytoplasm
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0022626	cellular_component	cytosolic ribosome
T	0022627	cellular_component	cytosolic small ribosomal subunit
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005737	cellular_component	cytoplasm
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0015935	cellular_component	small ribosomal subunit
U	0022626	cellular_component	cytosolic ribosome
Y	0003735	molecular_function	structural constituent of ribosome
Y	0022626	cellular_component	cytosolic ribosome

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsMMmhgrnnGKKlmtvrIVkhA

Chain	Residue	Details
E	GLU70-ALA96

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
b	LYS27-ASP52

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKtfnqveIkpemIGhyLGEFsiT

Chain	Residue	Details
O	ASN98-THR122

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvAQiyAirqSiSKAL

Chain	Residue	Details
Q	GLY74-LEU92

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkekNLkvkGPVrMPT

Chain	Residue	Details
U	ALA43-THR58

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsnrhglirkyg.LNMCRqCFR

Chain	Residue	Details
d	ARG22-ARG44

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfvdGlMihSgdpVnyyVDtavrhvlLrqGvlG

Chain	Residue	Details
B	ALA147-GLY183

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PshfsrgSksVaRrVLQaLE

Chain	Residue	Details
T	PRO89-GLU108

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHfwGlrVRGQ

Chain	Residue	Details
S	ARG121-GLN134

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSGswDgTLRLWDL

Chain	Residue	Details
g	ALA78-LEU92
g	ILE120-THR134
g	ILE165-LEU179
g	CYS207-LEU221

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IpSKkLRNkIAGYvTH

Chain	Residue	Details
R	ILE41-HIS56

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
c	GLU60-LEU68

site_id	PS01189
Number of Residues	19
Details	RIBOSOMAL_S12E Ribosomal protein S12e signature. ALQevLktAlihDGLarGI

Chain	Residue	Details
L	ALA17-ILE35

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)