9NPX
SARS-CoV-2 nsp1 bound to the Rhinolophus lepidus 40S ribosomal subunit (local refinement of the 40S body)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| a | 0003735 | molecular_function | structural constituent of ribosome |
| a | 0005840 | cellular_component | ribosome |
| a | 0006412 | biological_process | translation |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003735 | molecular_function | structural constituent of ribosome |
| A | 0005840 | cellular_component | ribosome |
| A | 0006412 | biological_process | translation |
| A | 0015935 | cellular_component | small ribosomal subunit |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003735 | molecular_function | structural constituent of ribosome |
| B | 0006412 | biological_process | translation |
| B | 0015935 | cellular_component | small ribosomal subunit |
| C | 0003735 | molecular_function | structural constituent of ribosome |
| C | 0005840 | cellular_component | ribosome |
| C | 0006412 | biological_process | translation |
| D | 0003723 | molecular_function | RNA binding |
| D | 0003735 | molecular_function | structural constituent of ribosome |
| D | 0005840 | cellular_component | ribosome |
| D | 0006412 | biological_process | translation |
| e | 0003735 | molecular_function | structural constituent of ribosome |
| e | 0005840 | cellular_component | ribosome |
| e | 0006412 | biological_process | translation |
| f | 0003735 | molecular_function | structural constituent of ribosome |
| f | 0005840 | cellular_component | ribosome |
| f | 0006412 | biological_process | translation |
| F | 0003735 | molecular_function | structural constituent of ribosome |
| F | 0005840 | cellular_component | ribosome |
| F | 0006412 | biological_process | translation |
| G | 0003735 | molecular_function | structural constituent of ribosome |
| G | 0005840 | cellular_component | ribosome |
| G | 0006412 | biological_process | translation |
| h | 0003735 | molecular_function | structural constituent of ribosome |
| h | 0005055 | molecular_function | laminin receptor activity |
| h | 0005840 | cellular_component | ribosome |
| h | 0006412 | biological_process | translation |
| h | 0015935 | cellular_component | small ribosomal subunit |
| H | 0003735 | molecular_function | structural constituent of ribosome |
| H | 0005840 | cellular_component | ribosome |
| H | 0006412 | biological_process | translation |
| I | 0003723 | molecular_function | RNA binding |
| I | 0003735 | molecular_function | structural constituent of ribosome |
| I | 0006412 | biological_process | translation |
| I | 0015935 | cellular_component | small ribosomal subunit |
| I | 0019843 | molecular_function | rRNA binding |
| k | 0003723 | molecular_function | RNA binding |
| k | 0003743 | molecular_function | translation initiation factor activity |
| k | 0005515 | molecular_function | protein binding |
| k | 0005634 | cellular_component | nucleus |
| k | 0005737 | cellular_component | cytoplasm |
| k | 0006412 | biological_process | translation |
| k | 0006413 | biological_process | translational initiation |
| k | 0006446 | biological_process | regulation of translational initiation |
| k | 0008135 | molecular_function | translation factor activity, RNA binding |
| k | 0010468 | biological_process | regulation of gene expression |
| k | 0016282 | cellular_component | eukaryotic 43S preinitiation complex |
| k | 0033290 | cellular_component | eukaryotic 48S preinitiation complex |
| k | 0043024 | molecular_function | ribosomal small subunit binding |
| k | 0043614 | cellular_component | multi-eIF complex |
| k | 0080090 | biological_process | regulation of primary metabolic process |
| K | 0003735 | molecular_function | structural constituent of ribosome |
| K | 0005840 | cellular_component | ribosome |
| K | 0006412 | biological_process | translation |
| M | 0003735 | molecular_function | structural constituent of ribosome |
| M | 0005840 | cellular_component | ribosome |
| M | 0006412 | biological_process | translation |
| N | 0003735 | molecular_function | structural constituent of ribosome |
| N | 0005840 | cellular_component | ribosome |
| N | 0006412 | biological_process | translation |
| P | 0003735 | molecular_function | structural constituent of ribosome |
| P | 0005840 | cellular_component | ribosome |
| P | 0006412 | biological_process | translation |
| R | 0003735 | molecular_function | structural constituent of ribosome |
| R | 0005840 | cellular_component | ribosome |
| R | 0006412 | biological_process | translation |
| V | 0003735 | molecular_function | structural constituent of ribosome |
| V | 0005840 | cellular_component | ribosome |
| V | 0006412 | biological_process | translation |
| W | 0003735 | molecular_function | structural constituent of ribosome |
| W | 0005840 | cellular_component | ribosome |
| W | 0006412 | biological_process | translation |
| W | 0015935 | cellular_component | small ribosomal subunit |
| X | 0003735 | molecular_function | structural constituent of ribosome |
| X | 0005840 | cellular_component | ribosome |
| X | 0006412 | biological_process | translation |
| Z | 0003735 | molecular_function | structural constituent of ribosome |
| Z | 0005840 | cellular_component | ribosome |
| Z | 0006412 | biological_process | translation |
Functional Information from PROSITE/UniProt
| site_id | PS00053 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_S8 Ribosomal protein S8 signature. GfiVLTTSaGIMdheeAR |
| Chain | Residue | Details |
| P | GLY100-ARG117 |
| site_id | PS00054 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GMkIgrieDvTPiPSD |
| Chain | Residue | Details |
| N | LEU116-IAS138 |
| site_id | PS00055 |
| Number of Residues | 8 |
| Details | RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR |
| Chain | Residue | Details |
| W | LYS60-ARG67 |
| site_id | PS00056 |
| Number of Residues | 13 |
| Details | RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgEcRPLS |
| Chain | Residue | Details |
| K | GLY123-SER135 |
| site_id | PS00362 |
| Number of Residues | 31 |
| Details | RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY |
| Chain | Residue | Details |
| M | VAL98-TYR128 |
| site_id | PS00528 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRVAaPkhWmLdK |
| Chain | Residue | Details |
| D | HIS8-LYS22 |
| site_id | PS00529 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKTtGFGmIYDSldyakknE |
| Chain | Residue | Details |
| X | PHE64-GLU86 |
| site_id | PS00548 |
| Number of Residues | 37 |
| Details | RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfvdGlMihSgdpVnyyVDtavrhvlLrqGvlG |
| Chain | Residue | Details |
| B | ALA147-GLY183 |
| site_id | PS00578 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM |
| Chain | Residue | Details |
| F | ILE52-MET63 |
| site_id | PS00585 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAfvAIGDyn.GhVGlGvkcsk.EVat.AI |
| Chain | Residue | Details |
| A | GLY119-ILE151 |
| site_id | PS00632 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVFKlglAkSihhARvLI |
| Chain | Residue | Details |
| I | LEU106-ILE130 |
| site_id | PS00712 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_S17E Ribosomal protein S17e signature. IpSKkLRNkIAGYvTH |
| Chain | Residue | Details |
| R | ILE41-HIS56 |
| site_id | PS00733 |
| Number of Residues | 8 |
| Details | RIBOSOMAL_S26E Ribosomal protein S26e signature. YCVSCAIH |
| Chain | Residue | Details |
| Z | TYR73-HIS80 |
| site_id | PS00948 |
| Number of Residues | 14 |
| Details | RIBOSOMAL_S7E Ribosomal protein S7e signature. RLvRELEKKFSgKH |
| Chain | Residue | Details |
| G | ARG78-HIS91 |
| site_id | PS00962 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VlKFLAAGTHLG |
| Chain | Residue | Details |
| h | VAL15-GLY26 |
| site_id | PS00963 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlLVVtDpraDhqpLtEasyvNLP |
| Chain | Residue | Details |
| h | PRO119-PRO143 |
| site_id | PS00996 |
| Number of Residues | 9 |
| Details | RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA |
| Chain | Residue | Details |
| V | LEU11-ALA19 |
| site_id | PS01168 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgCykittvFShAqtvvlCvgCStvLcqPtG |
| Chain | Residue | Details |
| a | LYS36-GLY68 |
| site_id | PS01191 |
| Number of Residues | 13 |
| Details | RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVfEvSLaDL |
| Chain | Residue | Details |
| C | LEU62-LEU74 |
| site_id | PS01193 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_S8E Ribosomal protein S8e signature. RrkTGGkrkpy.HkKrKyELG |
| Chain | Residue | Details |
| H | ARG11-GLY30 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 31 |
| Details | Domain: {"description":"BetaCoV Nsp1 C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU01308","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Binds 40S ribosomal subunit","evidences":[{"source":"PubMed","id":"29987188","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
