Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9NO4

Cryo-EM structure of Csm/AcrIIIA2/enolase 3:2 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003723	molecular_function	RNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004527	molecular_function	exonuclease activity
A	0005524	molecular_function	ATP binding
A	0016740	molecular_function	transferase activity
A	0016787	molecular_function	hydrolase activity
A	0051607	biological_process	defense response to virus
B	0003723	molecular_function	RNA binding
B	0051607	biological_process	defense response to virus
C	0003723	molecular_function	RNA binding
C	0051607	biological_process	defense response to virus
D	0003723	molecular_function	RNA binding
D	0051607	biological_process	defense response to virus
E	0003723	molecular_function	RNA binding
E	0004518	molecular_function	nuclease activity
E	0004519	molecular_function	endonuclease activity
E	0016787	molecular_function	hydrolase activity
E	0051607	biological_process	defense response to virus
F	0003723	molecular_function	RNA binding
F	0004518	molecular_function	nuclease activity
F	0004519	molecular_function	endonuclease activity
F	0016787	molecular_function	hydrolase activity
F	0051607	biological_process	defense response to virus
G	0003723	molecular_function	RNA binding
G	0004518	molecular_function	nuclease activity
G	0004519	molecular_function	endonuclease activity
G	0016787	molecular_function	hydrolase activity
G	0051607	biological_process	defense response to virus
H	0003723	molecular_function	RNA binding
H	0051607	biological_process	defense response to virus
I	0000015	cellular_component	phosphopyruvate hydratase complex
I	0000287	molecular_function	magnesium ion binding
I	0004634	molecular_function	phosphopyruvate hydratase activity
I	0005576	cellular_component	extracellular region
I	0005737	cellular_component	cytoplasm
I	0006096	biological_process	glycolytic process
I	0009274	cellular_component	peptidoglycan-based cell wall
I	0009986	cellular_component	cell surface
I	0016829	molecular_function	lyase activity
I	0046872	molecular_function	metal ion binding
J	0000015	cellular_component	phosphopyruvate hydratase complex
J	0000287	molecular_function	magnesium ion binding
J	0004634	molecular_function	phosphopyruvate hydratase activity
J	0005576	cellular_component	extracellular region
J	0005737	cellular_component	cytoplasm
J	0006096	biological_process	glycolytic process
J	0009274	cellular_component	peptidoglycan-based cell wall
J	0009986	cellular_component	cell surface
J	0016829	molecular_function	lyase activity
J	0046872	molecular_function	metal ion binding
K	0000015	cellular_component	phosphopyruvate hydratase complex
K	0000287	molecular_function	magnesium ion binding
K	0004634	molecular_function	phosphopyruvate hydratase activity
K	0005576	cellular_component	extracellular region
K	0005737	cellular_component	cytoplasm
K	0006096	biological_process	glycolytic process
K	0009274	cellular_component	peptidoglycan-based cell wall
K	0009986	cellular_component	cell surface
K	0016829	molecular_function	lyase activity
K	0046872	molecular_function	metal ion binding
L	0000015	cellular_component	phosphopyruvate hydratase complex
L	0000287	molecular_function	magnesium ion binding
L	0004634	molecular_function	phosphopyruvate hydratase activity
L	0005576	cellular_component	extracellular region
L	0005737	cellular_component	cytoplasm
L	0006096	biological_process	glycolytic process
L	0009274	cellular_component	peptidoglycan-based cell wall
L	0009986	cellular_component	cell surface
L	0016829	molecular_function	lyase activity
L	0046872	molecular_function	metal ion binding
M	0000015	cellular_component	phosphopyruvate hydratase complex
M	0000287	molecular_function	magnesium ion binding
M	0004634	molecular_function	phosphopyruvate hydratase activity
M	0005576	cellular_component	extracellular region
M	0005737	cellular_component	cytoplasm
M	0006096	biological_process	glycolytic process
M	0009274	cellular_component	peptidoglycan-based cell wall
M	0009986	cellular_component	cell surface
M	0016829	molecular_function	lyase activity
M	0046872	molecular_function	metal ion binding
O	0000015	cellular_component	phosphopyruvate hydratase complex
O	0000287	molecular_function	magnesium ion binding
O	0004634	molecular_function	phosphopyruvate hydratase activity
O	0005576	cellular_component	extracellular region
O	0005737	cellular_component	cytoplasm
O	0006096	biological_process	glycolytic process
O	0009274	cellular_component	peptidoglycan-based cell wall
O	0009986	cellular_component	cell surface
O	0016829	molecular_function	lyase activity
O	0046872	molecular_function	metal ion binding
P	0000015	cellular_component	phosphopyruvate hydratase complex
P	0000287	molecular_function	magnesium ion binding
P	0004634	molecular_function	phosphopyruvate hydratase activity
P	0005576	cellular_component	extracellular region
P	0005737	cellular_component	cytoplasm
P	0006096	biological_process	glycolytic process
P	0009274	cellular_component	peptidoglycan-based cell wall
P	0009986	cellular_component	cell surface
P	0016829	molecular_function	lyase activity
P	0046872	molecular_function	metal ion binding
Q	0000015	cellular_component	phosphopyruvate hydratase complex
Q	0000287	molecular_function	magnesium ion binding
Q	0004634	molecular_function	phosphopyruvate hydratase activity
Q	0005576	cellular_component	extracellular region
Q	0005737	cellular_component	cytoplasm
Q	0006096	biological_process	glycolytic process
Q	0009274	cellular_component	peptidoglycan-based cell wall
Q	0009986	cellular_component	cell surface
Q	0016829	molecular_function	lyase activity
Q	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00164
Number of Residues	14
Details	ENOLASE Enolase signature. ILIKvNQIGTLTET

Chain	Residue	Details
I	ILE340-THR353

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI3
Number of Residues	8
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	8
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	64
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	138
Details	Domain: {"description":"GGDEF","evidences":[{"source":"PROSITE-ProRule","id":"PRU00095","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"27105119","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	81
Details	Region: {"description":"HD domain","evidences":[{"source":"PubMed","id":"27105119","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)