9NKJ
Structure of substrates-engaged MIDN-bound human 26S proteasome,ED-MIDN state (Composite map)
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00012 |
| Number of Residues | 16 |
| Details | PHOSPHOPANTETHEINE Phosphopantetheine attachment site. AAGFSSSGPAATSGAV |
| Chain | Residue | Details |
| d | ALA-21-VAL-6 |
| site_id | PS00388 |
| Number of Residues | 23 |
| Details | PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdrgvNtFSPeGRlfQVEYAieA |
| Chain | Residue | Details |
| k | TYR8-ALA30 | |
| g | PHE9-ALA31 | |
| l | TYR6-ALA28 | |
| m | TYR7-ALA29 | |
| h | TYR5-ALA27 | |
| j | TYR3-ALA25 | |
| i | TYR5-ALA27 |
| site_id | PS00674 |
| Number of Residues | 19 |
| Details | AAA AAA-protein family signature. VkVImATNradtLDpALl.R |
| Chain | Residue | Details |
| D | VAL305-ARG323 | |
| A | ILE315-ARG333 | |
| F | VAL326-ARG344 | |
| E | VAL273-ARG291 | |
| C | ILE289-ARG307 | |
| B | VAL325-ARG343 |
| site_id | PS00854 |
| Number of Residues | 48 |
| Details | PROTEASOME_BETA_1 Proteasome beta-type subunits signature. AGVvYkdGIVLGADtrategmvvadkncs.KihfispniyccgaGtaAD |
| Chain | Residue | Details |
| O | ALA5-ASP52 | |
| Q | ILE5-ASP52 | |
| S | LEU13-ASP60 | |
| i | LEU35-ASP82 | |
| N | MET5-ASP52 | |
| T | LEU12-ASP59 | |
| R | LEU5-ASP52 | |
| P | MET11-ASP58 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| T | MET-44 | |
| t | MET-44 | |
| G | SER64 | |
| g | SER17 | |
| g | SER63 | |
| g | SER64 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| T | SER-19 | |
| t | SER-19 | |
| S | SER134 | |
| s | SER34 | |
| s | SER40 | |
| s | SER134 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:15592455 |
| Chain | Residue | Details |
| T | TYR57 | |
| t | TYR57 | |
| i | LYS127 | |
| i | LYS176 | |
| h | SER13 | |
| h | SER15 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| S | LYS176 | |
| s | LYS176 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | CARBOHYD: O-linked (GlcNAc) serine => ECO:0000250 |
| Chain | Residue | Details |
| S | SER30 | |
| S | SER181 | |
| s | SER30 | |
| s | SER181 | |
| l | LYS208 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: O-linked (GlcNAc) serine => ECO:0000250 |
| Chain | Residue | Details |
| K | SER198 | |
| k | SER198 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P17220 |
| Chain | Residue | Details |
| H | TYR120 | |
| h | TYR120 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| f | SER363 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q8VDM4 |
| Chain | Residue | Details |
| f | LYS551 |
