9MJG

Crystal structure of HAT1 in complex with XS380871

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004402	molecular_function	histone acetyltransferase activity
A	0005634	cellular_component	nucleus
A	0006325	biological_process	chromatin organization
A	0031509	biological_process	subtelomeric heterochromatin formation
A	0042393	molecular_function	histone binding
B	0004402	molecular_function	histone acetyltransferase activity
B	0005634	cellular_component	nucleus
B	0006325	biological_process	chromatin organization
B	0031509	biological_process	subtelomeric heterochromatin formation
B	0042393	molecular_function	histone binding
C	0004402	molecular_function	histone acetyltransferase activity
C	0005634	cellular_component	nucleus
C	0006325	biological_process	chromatin organization
C	0031509	biological_process	subtelomeric heterochromatin formation
C	0042393	molecular_function	histone binding
D	0004402	molecular_function	histone acetyltransferase activity
D	0005634	cellular_component	nucleus
D	0006325	biological_process	chromatin organization
D	0031509	biological_process	subtelomeric heterochromatin formation
D	0042393	molecular_function	histone binding
E	0004402	molecular_function	histone acetyltransferase activity
E	0005634	cellular_component	nucleus
E	0006325	biological_process	chromatin organization
E	0031509	biological_process	subtelomeric heterochromatin formation
E	0042393	molecular_function	histone binding
F	0004402	molecular_function	histone acetyltransferase activity
F	0005634	cellular_component	nucleus
F	0006325	biological_process	chromatin organization
F	0031509	biological_process	subtelomeric heterochromatin formation
F	0042393	molecular_function	histone binding
G	0004402	molecular_function	histone acetyltransferase activity
G	0005634	cellular_component	nucleus
G	0006325	biological_process	chromatin organization
G	0031509	biological_process	subtelomeric heterochromatin formation
G	0042393	molecular_function	histone binding
H	0004402	molecular_function	histone acetyltransferase activity
H	0005634	cellular_component	nucleus
H	0006325	biological_process	chromatin organization
H	0031509	biological_process	subtelomeric heterochromatin formation
H	0042393	molecular_function	histone binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton donor/acceptor => ECO:0000303|PubMed:22615379

Chain	Residue	Details
A	GLU276
B	GLU276
C	GLU276
D	GLU276
E	GLU276
F	GLU276
G	GLU276
H	GLU276

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site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:22615379

Chain	Residue	Details
A	MET241
E	GLN248
F	MET241
F	GLN248
G	MET241
G	GLN248
H	MET241
H	GLN248
A	GLN248
B	MET241
B	GLN248
C	MET241
C	GLN248
D	MET241
D	GLN248
E	MET241

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site_id	SWS_FT_FI3
Number of Residues	8
Details	SITE: Interaction with histone H4 N-terminus => ECO:0000269|PubMed:22615379

Chain	Residue	Details
A	TRP199
B	TRP199
C	TRP199
D	TRP199
E	TRP199
F	TRP199
G	TRP199
H	TRP199

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site_id	SWS_FT_FI4
Number of Residues	8
Details	MOD_RES: Phosphoserine; by AMPK => ECO:0000269|PubMed:28143904

Chain	Residue	Details
A	SER190
B	SER190
C	SER190
D	SER190
E	SER190
F	SER190
G	SER190
H	SER190

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