9MJG

Crystal structure of HAT1 in complex with XS380871

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004402	molecular_function	histone acetyltransferase activity
A	0005634	cellular_component	nucleus
A	0006325	biological_process	chromatin organization
A	0031509	biological_process	subtelomeric heterochromatin formation
A	0042393	molecular_function	histone binding
B	0004402	molecular_function	histone acetyltransferase activity
B	0005634	cellular_component	nucleus
B	0006325	biological_process	chromatin organization
B	0031509	biological_process	subtelomeric heterochromatin formation
B	0042393	molecular_function	histone binding
C	0004402	molecular_function	histone acetyltransferase activity
C	0005634	cellular_component	nucleus
C	0006325	biological_process	chromatin organization
C	0031509	biological_process	subtelomeric heterochromatin formation
C	0042393	molecular_function	histone binding
D	0004402	molecular_function	histone acetyltransferase activity
D	0005634	cellular_component	nucleus
D	0006325	biological_process	chromatin organization
D	0031509	biological_process	subtelomeric heterochromatin formation
D	0042393	molecular_function	histone binding
E	0004402	molecular_function	histone acetyltransferase activity
E	0005634	cellular_component	nucleus
E	0006325	biological_process	chromatin organization
E	0031509	biological_process	subtelomeric heterochromatin formation
E	0042393	molecular_function	histone binding
F	0004402	molecular_function	histone acetyltransferase activity
F	0005634	cellular_component	nucleus
F	0006325	biological_process	chromatin organization
F	0031509	biological_process	subtelomeric heterochromatin formation
F	0042393	molecular_function	histone binding
G	0004402	molecular_function	histone acetyltransferase activity
G	0005634	cellular_component	nucleus
G	0006325	biological_process	chromatin organization
G	0031509	biological_process	subtelomeric heterochromatin formation
G	0042393	molecular_function	histone binding
H	0004402	molecular_function	histone acetyltransferase activity
H	0005634	cellular_component	nucleus
H	0006325	biological_process	chromatin organization
H	0031509	biological_process	subtelomeric heterochromatin formation
H	0042393	molecular_function	histone binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	16
Details	Region: {"description":"Interaction with histone H4 N-terminus","evidences":[{"source":"PubMed","id":"22615379","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Region: {"description":"Interaction with histone H4 N-terminus","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"22615379","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Site: {"description":"Interaction with histone H4 N-terminus","evidences":[{"source":"PubMed","id":"22615379","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	64
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22615379","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine; by AMPK","evidences":[{"source":"PubMed","id":"28143904","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---