9MIR

CryoEM structure of ALK3-ActRIIB bound to BMP6

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
A	0005524	molecular_function	ATP binding
A	0007178	biological_process	cell surface receptor protein serine/threonine kinase signaling pathway
A	0016020	cellular_component	membrane
B	0005576	cellular_component	extracellular region
B	0008083	molecular_function	growth factor activity
C	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
C	0016020	cellular_component	membrane
D	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
D	0016020	cellular_component	membrane
E	0005576	cellular_component	extracellular region
E	0008083	molecular_function	growth factor activity
F	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
F	0005524	molecular_function	ATP binding
F	0007178	biological_process	cell surface receptor protein serine/threonine kinase signaling pathway
F	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00250
Number of Residues	16
Details	TGF_BETA_1 TGF-beta family signature. IiaPkgYaanyCdGeC

Chain	Residue	Details
E	ILE430-CYS445

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