9MFF
Structure of zebrafish OTOP1 in nanodisc in complex with inhibitor C2.2
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0005902 | cellular_component | microvillus |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0015252 | molecular_function | proton channel activity |
| A | 0015485 | molecular_function | cholesterol binding |
| A | 0016020 | cellular_component | membrane |
| A | 0031214 | biological_process | biomineral tissue development |
| A | 0032475 | biological_process | otolith formation |
| A | 0032869 | biological_process | cellular response to insulin stimulus |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0042472 | biological_process | inner ear morphogenesis |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0045299 | biological_process | otolith mineralization |
| A | 0060336 | biological_process | negative regulation of type II interferon-mediated signaling pathway |
| A | 1902600 | biological_process | proton transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0005902 | cellular_component | microvillus |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0015252 | molecular_function | proton channel activity |
| B | 0015485 | molecular_function | cholesterol binding |
| B | 0016020 | cellular_component | membrane |
| B | 0031214 | biological_process | biomineral tissue development |
| B | 0032475 | biological_process | otolith formation |
| B | 0032869 | biological_process | cellular response to insulin stimulus |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0042472 | biological_process | inner ear morphogenesis |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0045299 | biological_process | otolith mineralization |
| B | 0060336 | biological_process | negative regulation of type II interferon-mediated signaling pathway |
| B | 1902600 | biological_process | proton transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 42 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"31160780","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 70 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"31160780","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 44 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"31160780","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 48 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"31160780","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 50 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"31160780","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 50 |
| Details | Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"31160780","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 48 |
| Details | Transmembrane: {"description":"Helical; Name=9","evidences":[{"source":"PubMed","id":"31160780","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=10","evidences":[{"source":"PubMed","id":"31160780","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 36 |
| Details | Transmembrane: {"description":"Helical; Name=11","evidences":[{"source":"PubMed","id":"31160780","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 46 |
| Details | Transmembrane: {"description":"Helical; Name=12","evidences":[{"source":"PubMed","id":"31160780","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
