9LW4

UbCh8-ISG15 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000209	biological_process	protein polyubiquitination
B	0004842	molecular_function	ubiquitin-protein transferase activity
B	0005515	molecular_function	protein binding
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006511	biological_process	ubiquitin-dependent protein catabolic process
B	0016567	biological_process	protein ubiquitination
B	0019787	molecular_function	ubiquitin-like protein transferase activity
B	0032020	biological_process	ISG15-protein conjugation
B	0032446	biological_process	protein modification by small protein conjugation
B	0036211	biological_process	protein modification process
B	0042296	molecular_function	ISG15 transferase activity
B	0045087	biological_process	innate immune response
B	0061631	molecular_function	ubiquitin conjugating enzyme activity
B	0061650	molecular_function	ubiquitin-like protein conjugating enzyme activity
B	0061653	molecular_function	ISG15 conjugating enzyme activity
C	0000209	biological_process	protein polyubiquitination
C	0004842	molecular_function	ubiquitin-protein transferase activity
C	0005515	molecular_function	protein binding
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006511	biological_process	ubiquitin-dependent protein catabolic process
C	0016567	biological_process	protein ubiquitination
C	0019787	molecular_function	ubiquitin-like protein transferase activity
C	0032020	biological_process	ISG15-protein conjugation
C	0032446	biological_process	protein modification by small protein conjugation
C	0036211	biological_process	protein modification process
C	0042296	molecular_function	ISG15 transferase activity
C	0045087	biological_process	innate immune response
C	0061631	molecular_function	ubiquitin conjugating enzyme activity
C	0061650	molecular_function	ubiquitin-like protein conjugating enzyme activity
C	0061653	molecular_function	ISG15 conjugating enzyme activity

Functional Information from PROSITE/UniProt

site_id	PS00183
Number of Residues	16
Details	UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNVden.GqICLpiI

Chain	Residue	Details
B	TYR75-ILE90

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	294
Details	Domain: {"description":"UBC core","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10133","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Site: {"description":"Interacts with activating enzyme","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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