9LUS

Structure of human G9a SET-domain in complex with FLAV27 inhibitor

This is a non-PDB format compatible entry.

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	126
Details	Domain: {"description":"Pre-SET","evidences":[{"source":"PROSITE-ProRule","id":"PRU00157","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	32
Details	Domain: {"description":"Post-SET"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	6
Details	Region: {"description":"Interaction with histone H3","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20084102","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24900801","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2O8J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NVQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20084102","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2O8J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NVQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27648579","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5T0M","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20084102","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2O8J","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI8
Number of Residues	2
Details	Site: {"description":"Histone H3K9me binding","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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