9LJG

Cryo-EM structure of human organic solute transporter OSTalpha/beta in apo state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005886	cellular_component	plasma membrane
A	0006869	biological_process	lipid transport
A	0015125	molecular_function	bile acid transmembrane transporter activity
A	0015721	biological_process	bile acid and bile salt transport
A	0016020	cellular_component	membrane
A	0016323	cellular_component	basolateral plasma membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0032782	biological_process	bile acid secretion
A	0032991	cellular_component	protein-containing complex
A	0042803	molecular_function	protein homodimerization activity
A	0046982	molecular_function	protein heterodimerization activity
A	0055085	biological_process	transmembrane transport
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006869	biological_process	lipid transport
B	0010560	biological_process	positive regulation of glycoprotein biosynthetic process
B	0015125	molecular_function	bile acid transmembrane transporter activity
B	0015721	biological_process	bile acid and bile salt transport
B	0016020	cellular_component	membrane
B	0016323	cellular_component	basolateral plasma membrane
B	0022857	molecular_function	transmembrane transporter activity
B	0031647	biological_process	regulation of protein stability
B	0032782	biological_process	bile acid secretion
B	0032991	cellular_component	protein-containing complex
B	0046982	molecular_function	protein heterodimerization activity
B	0055085	biological_process	transmembrane transport
B	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
B	0090314	biological_process	positive regulation of protein targeting to membrane
C	0005515	molecular_function	protein binding
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0005886	cellular_component	plasma membrane
C	0006869	biological_process	lipid transport
C	0015125	molecular_function	bile acid transmembrane transporter activity
C	0015721	biological_process	bile acid and bile salt transport
C	0016020	cellular_component	membrane
C	0016323	cellular_component	basolateral plasma membrane
C	0022857	molecular_function	transmembrane transporter activity
C	0032782	biological_process	bile acid secretion
C	0032991	cellular_component	protein-containing complex
C	0042803	molecular_function	protein homodimerization activity
C	0046982	molecular_function	protein heterodimerization activity
C	0055085	biological_process	transmembrane transport
D	0005515	molecular_function	protein binding
D	0005886	cellular_component	plasma membrane
D	0006869	biological_process	lipid transport
D	0010560	biological_process	positive regulation of glycoprotein biosynthetic process
D	0015125	molecular_function	bile acid transmembrane transporter activity
D	0015721	biological_process	bile acid and bile salt transport
D	0016020	cellular_component	membrane
D	0016323	cellular_component	basolateral plasma membrane
D	0022857	molecular_function	transmembrane transporter activity
D	0031647	biological_process	regulation of protein stability
D	0032782	biological_process	bile acid secretion
D	0032991	cellular_component	protein-containing complex
D	0046982	molecular_function	protein heterodimerization activity
D	0055085	biological_process	transmembrane transport
D	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
D	0090314	biological_process	positive regulation of protein targeting to membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	324
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	146
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	82
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---