9KBZ
Cryo-EM structure of DCL4-DRB4CTD-dsRNA complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005829 | cellular_component | cytosol |
| A | 0006353 | biological_process | DNA-templated transcription termination |
| A | 0009616 | biological_process | RNAi-mediated antiviral immune response |
| A | 0009944 | biological_process | polarity specification of adaxial/abaxial axis |
| A | 0010050 | biological_process | vegetative phase change |
| A | 0010267 | biological_process | ta-siRNA processing |
| A | 0010492 | biological_process | maintenance of shoot apical meristem identity |
| A | 0010599 | biological_process | lsiRNA processing |
| A | 0036464 | cellular_component | cytoplasmic ribonucleoprotein granule |
| A | 0044027 | biological_process | negative regulation of gene expression via chromosomal CpG island methylation |
| A | 0048608 | biological_process | reproductive structure development |
| A | 0051214 | biological_process | RNAi-mediated antiviral immunity against RNA virus |
| A | 0051607 | biological_process | defense response to virus |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 176 |
| Details | Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 154 |
| Details | Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 66 |
| Details | Domain: {"description":"DRBM 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00266","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 76 |
| Details | Domain: {"description":"DRBM 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00266","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Motif: {"description":"DECH box"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for activity","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
