9K2E

Crystal structure of mSMPDL3B-dimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002376	biological_process	immune system process
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005886	cellular_component	plasma membrane
A	0006629	biological_process	lipid metabolic process
A	0006954	biological_process	inflammatory response
A	0008081	molecular_function	phosphoric diester hydrolase activity
A	0008270	molecular_function	zinc ion binding
A	0016042	biological_process	lipid catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0034122	biological_process	negative regulation of toll-like receptor signaling pathway
A	0045087	biological_process	innate immune response
A	0045824	biological_process	negative regulation of innate immune response
A	0046466	biological_process	membrane lipid catabolic process
A	0046872	molecular_function	metal ion binding
A	0050728	biological_process	negative regulation of inflammatory response
A	0098552	cellular_component	side of membrane
B	0002376	biological_process	immune system process
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005886	cellular_component	plasma membrane
B	0006629	biological_process	lipid metabolic process
B	0006954	biological_process	inflammatory response
B	0008081	molecular_function	phosphoric diester hydrolase activity
B	0008270	molecular_function	zinc ion binding
B	0016042	biological_process	lipid catabolic process
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0034122	biological_process	negative regulation of toll-like receptor signaling pathway
B	0045087	biological_process	innate immune response
B	0045824	biological_process	negative regulation of innate immune response
B	0046466	biological_process	membrane lipid catabolic process
B	0046872	molecular_function	metal ion binding
B	0050728	biological_process	negative regulation of inflammatory response
B	0098552	cellular_component	side of membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27687724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KAR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19656770","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27687724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KAR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"27687724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KAR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---