9K0X
Cryo-EM structure of ATP-bound P2Y purinoceptor 2-miniGq-Nb35 complex
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. CSIlFLTCISVHRCLgV |
| Chain | Residue | Details |
| I | CYS119-VAL135 |
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSAsqDgKLIIWDS |
| Chain | Residue | Details |
| B | LEU70-SER84 | |
| B | ILE157-ILE171 | |
| B | LEU285-ALA299 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 85 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| I | MET1-LYS32 | |
| I | ALA94-ARG110 | |
| I | THR173-ARG194 | |
| I | SER270-ALA287 | |
| A | LEU302 | |
| A | PHE376 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 26 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000255 |
| Chain | Residue | Details |
| I | TYR33-LEU59 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 124 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| I | CYS60-THR70 | |
| I | HIS130-ARG152 | |
| I | MET221-THR246 | |
| I | GLY310-LEU377 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| I | TYR71-TYR93 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| I | PHE111-VAL129 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 19 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| I | VAL153-VAL172 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 25 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| I | PHE195-LEU220 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| I | ILE247-TYR269 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| I | TYR288-ALA309 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| I | ASN9 | |
| I | ASN13 |
