9JQP

Cryo-EM structure of the HMBPP-primed BTN3A1-BTN3A2-BTN2A1 in complex with agonist antibody TH001

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001817	biological_process	regulation of cytokine production
A	0001819	biological_process	positive regulation of cytokine production
A	0002250	biological_process	adaptive immune response
A	0002376	biological_process	immune system process
A	0005102	molecular_function	signaling receptor binding
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0009897	cellular_component	external side of plasma membrane
A	0032729	biological_process	positive regulation of type II interferon production
A	0050798	biological_process	activated T cell proliferation
A	0050852	biological_process	T cell receptor signaling pathway
B	0001817	biological_process	regulation of cytokine production
B	0002250	biological_process	adaptive immune response
B	0002376	biological_process	immune system process
B	0002456	biological_process	T cell mediated immunity
B	0005102	molecular_function	signaling receptor binding
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0009897	cellular_component	external side of plasma membrane
B	0016020	cellular_component	membrane
B	0032729	biological_process	positive regulation of type II interferon production
B	0050852	biological_process	T cell receptor signaling pathway
E	0001817	biological_process	regulation of cytokine production
E	0005102	molecular_function	signaling receptor binding
E	0005886	cellular_component	plasma membrane
E	0006629	biological_process	lipid metabolic process
E	0009897	cellular_component	external side of plasma membrane
E	0016020	cellular_component	membrane
E	0050852	biological_process	T cell receptor signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	91
Details	Domain: {"description":"Ig-like V-type 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22846996","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	221
Details	Domain: {"description":"Ig-like V-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---