9JQ6

Cryo-EM structure of BTN2A1 in complex with antagonist antibody TH002

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0001817	biological_process	regulation of cytokine production
E	0005102	molecular_function	signaling receptor binding
E	0005886	cellular_component	plasma membrane
E	0006629	biological_process	lipid metabolic process
E	0009897	cellular_component	external side of plasma membrane
E	0016020	cellular_component	membrane
E	0050852	biological_process	T cell receptor signaling pathway
F	0001817	biological_process	regulation of cytokine production
F	0005102	molecular_function	signaling receptor binding
F	0005886	cellular_component	plasma membrane
F	0006629	biological_process	lipid metabolic process
F	0009897	cellular_component	external side of plasma membrane
F	0016020	cellular_component	membrane
F	0050852	biological_process	T cell receptor signaling pathway

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
I	TYR196-HIS202

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	224
Details	Domain: {"description":"Ig-like V-type"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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