9J56
Functional Investigation of the SAM-Dependent Methyltransferases Rdmb in Anthracycline Biosynthesis
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0017000 | biological_process | antibiotic biosynthetic process |
| A | 0032259 | biological_process | methylation |
| A | 0046983 | molecular_function | protein dimerization activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008171 | molecular_function | O-methyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0017000 | biological_process | antibiotic biosynthetic process |
| B | 0032259 | biological_process | methylation |
| B | 0046983 | molecular_function | protein dimerization activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14607118","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1QZZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1R00","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14607118","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15548527","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1QZZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1R00","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XDS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Required for 4-O-methylation activity","evidences":[{"source":"PubMed","id":"39308748","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Required for 10-decarboxylative hydroxylation activity","evidences":[{"source":"PubMed","id":"39308748","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
