9IP4
Cryo-EM structure of the RNA-dependent RNA polymerase complex from Marburg virus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| A | 0004482 | molecular_function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006370 | biological_process | 7-methylguanosine mRNA capping |
| A | 0008643 | biological_process | carbohydrate transport |
| A | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0008643 | biological_process | carbohydrate transport |
| B | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0008643 | biological_process | carbohydrate transport |
| C | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0008643 | biological_process | carbohydrate transport |
| D | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| D | 0055085 | biological_process | transmembrane transport |
| E | 0008643 | biological_process | carbohydrate transport |
| E | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| E | 0055085 | biological_process | transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS01037 |
| Number of Residues | 18 |
| Details | SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN |
| Chain | Residue | Details |
| B | PRO-223-ASN-206 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 184 |
| Details | Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"40164610","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"40164610","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9IP2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9IP4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with VP35","evidences":[{"source":"PubMed","id":"40164610","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 125 |
| Details | Domain: {"description":"VP35 IID","evidences":[{"source":"PROSITE-ProRule","id":"PRU01071","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Site: {"description":"Interaction with L polymerase","evidences":[{"source":"PubMed","id":"40164610","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
