9HZ5

Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006605	biological_process	protein targeting
A	0006886	biological_process	intracellular protein transport
A	0008320	molecular_function	transmembrane protein transporter activity
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
B	0015031	biological_process	protein transport
B	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00755
Number of Residues	20
Details	SECY_1 Protein secY signature 1. TLMeLGIsPIVtSGLIMQLL

Chain	Residue	Details
B	THR75-LEU94

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site_id	PS01067
Number of Residues	29
Details	SECE_SEC61G Protein secE/sec61-gamma signature. FvKDsIrlVkRctKPdrkEfqkiaMATAI

Chain	Residue	Details
A	PHE14-ILE42

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