9HDH
Structure of s.c.Osh6 in complex with Ist2 732-761 and POPS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001786 | molecular_function | phosphatidylserine binding |
| A | 0005548 | molecular_function | phospholipid transporter activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006869 | biological_process | lipid transport |
| A | 0006887 | biological_process | exocytosis |
| A | 0006897 | biological_process | endocytosis |
| A | 0008289 | molecular_function | lipid binding |
| A | 0010314 | molecular_function | phosphatidylinositol-5-phosphate binding |
| A | 0015914 | biological_process | phospholipid transport |
| A | 0015918 | biological_process | sterol transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016125 | biological_process | sterol metabolic process |
| A | 0030011 | biological_process | maintenance of cell polarity |
| A | 0032541 | cellular_component | cortical endoplasmic reticulum |
| A | 0032934 | molecular_function | sterol binding |
| A | 0034727 | biological_process | piecemeal microautophagy of the nucleus |
| A | 0043325 | molecular_function | phosphatidylinositol-3,4-bisphosphate binding |
| A | 0055092 | biological_process | sterol homeostasis |
| A | 0070273 | molecular_function | phosphatidylinositol-4-phosphate binding |
| A | 0070300 | molecular_function | phosphatidic acid binding |
| A | 0080025 | molecular_function | phosphatidylinositol-3,5-bisphosphate binding |
| A | 0120015 | molecular_function | sterol transfer activity |
Functional Information from PROSITE/UniProt
| site_id | PS01013 |
| Number of Residues | 12 |
| Details | OSBP Oxysterol-binding protein family signature. EQtSHHPPecAY |
| Chain | Residue | Details |
| A | GLU153-TYR164 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 337 |
| Details | Region: {"description":"OSBP-related domain (ORD)","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23934110","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4B2Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26206936","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4PH7","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
