9H8T

Cryo-EM structure of the atovaquone-inhibited Complex III from the Chlorocebus sabaeus respirasome

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0005739	cellular_component	mitochondrion
a	0005743	cellular_component	mitochondrial inner membrane
a	0008121	molecular_function	quinol-cytochrome-c reductase activity
a	0016020	cellular_component	membrane
a	0022904	biological_process	respiratory electron transport chain
a	0031966	cellular_component	mitochondrial membrane
a	0034551	biological_process	mitochondrial respiratory chain complex III assembly
a	0045275	cellular_component	respiratory chain complex III
a	0051537	molecular_function	2 iron, 2 sulfur cluster binding
a	1902600	biological_process	proton transmembrane transport
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0008121	molecular_function	quinol-cytochrome-c reductase activity
A	0016020	cellular_component	membrane
A	0022904	biological_process	respiratory electron transport chain
A	0031966	cellular_component	mitochondrial membrane
A	0034551	biological_process	mitochondrial respiratory chain complex III assembly
A	0045275	cellular_component	respiratory chain complex III
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	1902600	biological_process	proton transmembrane transport
c	0005739	cellular_component	mitochondrion
c	0005743	cellular_component	mitochondrial inner membrane
c	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
c	0021539	biological_process	subthalamus development
c	0021548	biological_process	pons development
c	0021680	biological_process	cerebellar Purkinje cell layer development
c	0021766	biological_process	hippocampus development
c	0021794	biological_process	thalamus development
c	0021854	biological_process	hypothalamus development
c	0021860	biological_process	pyramidal neuron development
c	0030901	biological_process	midbrain development
c	0045275	cellular_component	respiratory chain complex III
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
C	0021539	biological_process	subthalamus development
C	0021548	biological_process	pons development
C	0021680	biological_process	cerebellar Purkinje cell layer development
C	0021766	biological_process	hippocampus development
C	0021794	biological_process	thalamus development
C	0021854	biological_process	hypothalamus development
C	0021860	biological_process	pyramidal neuron development
C	0030901	biological_process	midbrain development
C	0045275	cellular_component	respiratory chain complex III
d	0005739	cellular_component	mitochondrion
d	0005743	cellular_component	mitochondrial inner membrane
d	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
d	0009055	molecular_function	electron transfer activity
d	0020037	molecular_function	heme binding
d	0045275	cellular_component	respiratory chain complex III
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
D	0009055	molecular_function	electron transfer activity
D	0020037	molecular_function	heme binding
D	0045275	cellular_component	respiratory chain complex III
e	0005739	cellular_component	mitochondrion
e	0005743	cellular_component	mitochondrial inner membrane
e	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
e	0009060	biological_process	aerobic respiration
e	0016020	cellular_component	membrane
e	0045275	cellular_component	respiratory chain complex III
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
E	0009060	biological_process	aerobic respiration
E	0016020	cellular_component	membrane
E	0045275	cellular_component	respiratory chain complex III
f	0005743	cellular_component	mitochondrial inner membrane
f	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
f	0045275	cellular_component	respiratory chain complex III
F	0005743	cellular_component	mitochondrial inner membrane
F	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
F	0045275	cellular_component	respiratory chain complex III
g	0005743	cellular_component	mitochondrial inner membrane
g	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
g	0045275	cellular_component	respiratory chain complex III
G	0005743	cellular_component	mitochondrial inner membrane
G	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
G	0045275	cellular_component	respiratory chain complex III
h	0005743	cellular_component	mitochondrial inner membrane
h	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
h	0045275	cellular_component	respiratory chain complex III
H	0005743	cellular_component	mitochondrial inner membrane
H	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
H	0045275	cellular_component	respiratory chain complex III
j	0005739	cellular_component	mitochondrion
j	0005743	cellular_component	mitochondrial inner membrane
j	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
j	0008121	molecular_function	quinol-cytochrome-c reductase activity
j	0009055	molecular_function	electron transfer activity
j	0016020	cellular_component	membrane
j	0016491	molecular_function	oxidoreductase activity
j	0022900	biological_process	electron transport chain
j	0022904	biological_process	respiratory electron transport chain
j	0045275	cellular_component	respiratory chain complex III
j	0046872	molecular_function	metal ion binding
j	1902600	biological_process	proton transmembrane transport
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
J	0008121	molecular_function	quinol-cytochrome-c reductase activity
J	0009055	molecular_function	electron transfer activity
J	0016020	cellular_component	membrane
J	0016491	molecular_function	oxidoreductase activity
J	0022900	biological_process	electron transport chain
J	0022904	biological_process	respiratory electron transport chain
J	0045275	cellular_component	respiratory chain complex III
J	0046872	molecular_function	metal ion binding
J	1902600	biological_process	proton transmembrane transport
k	0004222	molecular_function	metalloendopeptidase activity
k	0005739	cellular_component	mitochondrion
k	0005743	cellular_component	mitochondrial inner membrane
k	0006508	biological_process	proteolysis
k	0045275	cellular_component	respiratory chain complex III
k	0046872	molecular_function	metal ion binding
K	0004222	molecular_function	metalloendopeptidase activity
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0006508	biological_process	proteolysis
K	0045275	cellular_component	respiratory chain complex III
K	0046872	molecular_function	metal ion binding
l	0005739	cellular_component	mitochondrion
l	0005743	cellular_component	mitochondrial inner membrane
l	0031625	molecular_function	ubiquitin protein ligase binding
l	0045275	cellular_component	respiratory chain complex III
l	0046872	molecular_function	metal ion binding
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0031625	molecular_function	ubiquitin protein ligase binding
L	0045275	cellular_component	respiratory chain complex III
L	0046872	molecular_function	metal ion binding
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0008121	molecular_function	quinol-cytochrome-c reductase activity
T	0016020	cellular_component	membrane
T	0022904	biological_process	respiratory electron transport chain
T	0031966	cellular_component	mitochondrial membrane
T	0034551	biological_process	mitochondrial respiratory chain complex III assembly
T	0045275	cellular_component	respiratory chain complex III
T	0051537	molecular_function	2 iron, 2 sulfur cluster binding
T	1902600	biological_process	proton transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsryedsnnlGtTHLLRLAsSlTT

Chain	Residue	Details
K	GLY68-THR91

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