9GOC

Crystal structure of DPP9 Ser730Ala in complex with sulphostin.

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004177	molecular_function	aminopeptidase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005829	cellular_component	cytosol
A	0005874	cellular_component	microtubule
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008236	molecular_function	serine-type peptidase activity
A	0008239	molecular_function	dipeptidyl-peptidase activity
A	0016787	molecular_function	hydrolase activity
A	0031252	cellular_component	cell leading edge
A	0042802	molecular_function	identical protein binding
A	0043069	biological_process	negative regulation of programmed cell death
A	0070269	biological_process	pyroptotic inflammatory response
B	0004177	molecular_function	aminopeptidase activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005829	cellular_component	cytosol
B	0005874	cellular_component	microtubule
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0008236	molecular_function	serine-type peptidase activity
B	0008239	molecular_function	dipeptidyl-peptidase activity
B	0016787	molecular_function	hydrolase activity
B	0031252	cellular_component	cell leading edge
B	0042802	molecular_function	identical protein binding
B	0043069	biological_process	negative regulation of programmed cell death
B	0070269	biological_process	pyroptotic inflammatory response
C	0004177	molecular_function	aminopeptidase activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005829	cellular_component	cytosol
C	0005874	cellular_component	microtubule
C	0006508	biological_process	proteolysis
C	0008233	molecular_function	peptidase activity
C	0008236	molecular_function	serine-type peptidase activity
C	0008239	molecular_function	dipeptidyl-peptidase activity
C	0016787	molecular_function	hydrolase activity
C	0031252	cellular_component	cell leading edge
C	0042802	molecular_function	identical protein binding
C	0043069	biological_process	negative regulation of programmed cell death
C	0070269	biological_process	pyroptotic inflammatory response
D	0004177	molecular_function	aminopeptidase activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005829	cellular_component	cytosol
D	0005874	cellular_component	microtubule
D	0006508	biological_process	proteolysis
D	0008233	molecular_function	peptidase activity
D	0008236	molecular_function	serine-type peptidase activity
D	0008239	molecular_function	dipeptidyl-peptidase activity
D	0016787	molecular_function	hydrolase activity
D	0031252	cellular_component	cell leading edge
D	0042802	molecular_function	identical protein binding
D	0043069	biological_process	negative regulation of programmed cell death
D	0070269	biological_process	pyroptotic inflammatory response

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"30291141","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"Q6V1X1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"33731932","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34019797","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7JN7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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